{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Crystalloid+administration",
    "query": {
      "intervention": "Crystalloid administration"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 455,
    "total_pages": 46,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Crystalloid+administration&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T12:05:28.403Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01917006",
      "title": "A Safety and Efficacy Study of OnabotulinumtoxinA in Premature Ejaculation",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Premature Ejaculation"
      ],
      "interventions": [
        {
          "name": "OnabotulinumtoxinA",
          "type": "DRUG"
        },
        {
          "name": "Normal Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Allergan",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "MALE",
        "summary": "18 Years to 50 Years · Male only"
      },
      "enrollment_count": 59,
      "start_date": "2013-08-07",
      "completion_date": "2017-08-15",
      "has_results": true,
      "last_update_posted_date": "2018-10-18",
      "last_synced_at": "2026-09-03T12:05:28.403Z",
      "location_count": 6,
      "location_summary": "San Diego, California • Torrance, California • Middlebury, Connecticut + 3 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Middlebury",
          "state": "Connecticut"
        },
        {
          "city": "West Palm Beach",
          "state": "Florida"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01917006"
    },
    {
      "nct_id": "NCT02749968",
      "title": "Intercostal Liposomal Bupivacaine for the Management of Blunt Chest Wall Trauma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Blunt Chest Wall Trauma",
        "Rib Fracture",
        "Sternal Fracture"
      ],
      "interventions": [
        {
          "name": "Liposomal bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "0.9% sodium chloride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2018-03-09",
      "completion_date": "2021-01-01",
      "has_results": true,
      "last_update_posted_date": "2022-04-04",
      "last_synced_at": "2026-09-03T12:05:28.403Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02749968"
    },
    {
      "nct_id": "NCT04904562",
      "title": "Angiotensin II for Distributive Shock",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Distributive Shock"
      ],
      "interventions": [
        {
          "name": "Angiotensin II",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2022-06-01",
      "completion_date": "2024-07-01",
      "has_results": true,
      "last_update_posted_date": "2026-04-13",
      "last_synced_at": "2026-09-03T12:05:28.403Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04904562"
    },
    {
      "nct_id": "NCT00606905",
      "title": "Intravenous Immunoglobulin (IVIG) for Treatment of Unexplained Secondary Recurrent Miscarriage",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Miscarriage, Recurrent",
        "Abortion, Habitual"
      ],
      "interventions": [
        {
          "name": "Gamimune N or Gamunex 10%",
          "type": "BIOLOGICAL"
        },
        {
          "name": "normal saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 82,
      "start_date": "1999-11",
      "completion_date": "2010-01",
      "has_results": true,
      "last_update_posted_date": "2012-10-08",
      "last_synced_at": "2026-09-03T12:05:28.403Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00606905"
    },
    {
      "nct_id": "NCT06111339",
      "title": "Ketamine for OUD and Suicidal Ideation in the ED",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Opioid Use Disorder",
        "Suicidal Ideation"
      ],
      "interventions": [
        {
          "name": "Ketamine",
          "type": "DRUG"
        },
        {
          "name": "Saline Solution",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2024-06-14",
      "completion_date": "2025-03-31",
      "has_results": false,
      "last_update_posted_date": "2025-04-08",
      "last_synced_at": "2026-09-03T12:05:28.403Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06111339"
    },
    {
      "nct_id": "NCT03185130",
      "title": "Intravenous Fluids in Benign Headaches Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Headache"
      ],
      "interventions": [
        {
          "name": "Normal Saline 5mL",
          "type": "DRUG"
        },
        {
          "name": "Normal Saline 20mL/kg",
          "type": "DRUG"
        },
        {
          "name": "Prochlorperazine 0.15 mg/kg up to 10 mg IV",
          "type": "DRUG"
        },
        {
          "name": "Diphenhydramine 1 mg/kg up to 50 mg IV",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University Medical Center of Southern Nevada",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "10 Years to 65 Years"
      },
      "enrollment_count": 58,
      "start_date": "2017-05-16",
      "completion_date": "2019-05-15",
      "has_results": true,
      "last_update_posted_date": "2024-06-06",
      "last_synced_at": "2026-09-03T12:05:28.403Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03185130"
    },
    {
      "nct_id": "NCT01600716",
      "title": "Safety and Efficacy Study of OnabotulinumtoxinA for the Treatment of Urinary Incontinence Due to Neurogenic Detrusor Overactivity (NDO) in Non-Catheterizing Patients With Multiple Sclerosis (MS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Urinary Incontinence",
        "Multiple Sclerosis",
        "Neurogenic Bladder"
      ],
      "interventions": [
        {
          "name": "OnabotulinumtoxinA",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo (Normal Saline)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "Allergan",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 144,
      "start_date": "2012-06-13",
      "completion_date": "2015-03-27",
      "has_results": true,
      "last_update_posted_date": "2019-04-30",
      "last_synced_at": "2026-09-03T12:05:28.403Z",
      "location_count": 1,
      "location_summary": "Mountlake Terrace, Washington",
      "locations": [
        {
          "city": "Mountlake Terrace",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01600716"
    },
    {
      "nct_id": "NCT01123837",
      "title": "A Closer Look at the Effect of Dextrose on Postoperative Nausea and Vomiting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postoperative Nausea and Vomiting"
      ],
      "interventions": [
        {
          "name": "Intravenous fluid",
          "type": "OTHER"
        },
        {
          "name": "D5LR or lactated ringers",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 65 Years · Female only"
      },
      "enrollment_count": 202,
      "start_date": "2010-04",
      "completion_date": "2013-09",
      "has_results": false,
      "last_update_posted_date": "2014-01-22",
      "last_synced_at": "2026-09-03T12:05:28.403Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01123837"
    },
    {
      "nct_id": "NCT01119079",
      "title": "Study to Determine Whether the Instillation of 10ml Normal Saline Improves Epidural Analgesia During Labor",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Parturients"
      ],
      "interventions": [
        {
          "name": "Normal Saline",
          "type": "OTHER"
        },
        {
          "name": "Administration of epidural anesthesia for labor",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "University of Medicine and Dentistry of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2010-03",
      "completion_date": "2012-09",
      "has_results": false,
      "last_update_posted_date": "2015-04-24",
      "last_synced_at": "2026-09-03T12:05:28.403Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01119079"
    },
    {
      "nct_id": "NCT04396795",
      "title": "Safety and Efficacy of Autologous Platelet-Rich Plasma for Erectile Dysfunction.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Erectile Dysfunction"
      ],
      "interventions": [
        {
          "name": "Autologous Platelet Rich Plasma",
          "type": "DRUG"
        },
        {
          "name": "Saline solution",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "75 Years",
        "sex": "MALE",
        "summary": "30 Years to 75 Years · Male only"
      },
      "enrollment_count": 61,
      "start_date": "2020-05-21",
      "completion_date": "2023-04-18",
      "has_results": true,
      "last_update_posted_date": "2024-01-09",
      "last_synced_at": "2026-09-03T12:05:28.403Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04396795"
    }
  ]
}