{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Curcumin-MTD",
    "query": {
      "intervention": "Curcumin-MTD"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 4,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-09T05:56:51.395Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01201694",
      "title": "Phase I Study of Surface-Controlled Water Soluble Curcumin (THERACURMIN CR-011L)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Advanced Cancers"
      ],
      "interventions": [
        {
          "name": "Surface-Controlled Water Soluble Curcumin",
          "type": "DRUG"
        },
        {
          "name": "Surface-Controlled Water Soluble Curcumin MTD",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "13 Years and older"
      },
      "enrollment_count": 28,
      "start_date": "2011-10",
      "completion_date": "2014-01",
      "has_results": false,
      "last_update_posted_date": "2015-01-08",
      "last_synced_at": "2026-09-09T05:56:51.395Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01201694"
    },
    {
      "nct_id": "NCT02300727",
      "title": "Study to See How Safe Curcumin is and How Well it Works When Used to Treat Mucositis in Patients Getting Chemotherapy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Mucositis"
      ],
      "interventions": [
        {
          "name": "Curcumin-MTD",
          "type": "DRUG"
        },
        {
          "name": "Mouthwash-standard pharmacy preparation",
          "type": "DRUG"
        },
        {
          "name": "Curcumin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Amy Beres",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2015-02",
      "completion_date": "2018-10-25",
      "has_results": true,
      "last_update_posted_date": "2019-05-31",
      "last_synced_at": "2026-09-09T05:56:51.395Z",
      "location_count": 1,
      "location_summary": "Green Bay, Wisconsin",
      "locations": [
        {
          "city": "Green Bay",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02300727"
    },
    {
      "nct_id": "NCT01859858",
      "title": "Effect of Curcumin on Dose Limiting Toxicity and Pharmacokinetics of Irinotecan in Patients With Solid Tumors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Advanced Colorectal Cancer"
      ],
      "interventions": [
        {
          "name": "curcumin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Irinotecan",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "DRUG"
      ],
      "sponsor": "UNC Lineberger Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "21 Years to 99 Years"
      },
      "enrollment_count": 23,
      "start_date": "2013-06",
      "completion_date": "2016-10-05",
      "has_results": false,
      "last_update_posted_date": "2023-12-04",
      "last_synced_at": "2026-09-09T05:56:51.395Z",
      "location_count": 2,
      "location_summary": "Indianapolis, Indiana • Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01859858"
    },
    {
      "nct_id": "NCT05768919",
      "title": "Study of Liposomal Curcumin in Combination With RT and TMZ in Patients With Newly Diagnosed High-Grade Gliomas",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Glioblastoma"
      ],
      "interventions": [
        {
          "name": "Treatment Period 1",
          "type": "DRUG"
        },
        {
          "name": "Treatment Period 2",
          "type": "DRUG"
        },
        {
          "name": "Treatment Period 3",
          "type": "DRUG"
        },
        {
          "name": "Treatment Period 4a",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "SignPath Pharma, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2023-03-03",
      "completion_date": "2027-05",
      "has_results": false,
      "last_update_posted_date": "2024-11-29",
      "last_synced_at": "2026-09-09T05:56:51.395Z",
      "location_count": 2,
      "location_summary": "Washington D.C., District of Columbia • Baltimore, Maryland",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05768919"
    }
  ]
}