{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=DBS+Off",
    "query": {
      "intervention": "DBS Off"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 72,
    "total_pages": 8,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=DBS+Off&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-11T20:27:03.356Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06164717",
      "title": "Behavioral and Neural Characteristics of Adaptive Speech Motor Control",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Speech"
      ],
      "interventions": [
        {
          "name": "Auditory feedback perturbation during speech",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Visual feedback perturbation during reaching",
          "type": "BEHAVIORAL"
        },
        {
          "name": "DBS stimulation ON/OFF",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "4 Years and older"
      },
      "enrollment_count": 507,
      "start_date": "2023-01-01",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-12-11",
      "last_synced_at": "2026-09-11T20:27:03.356Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06164717"
    },
    {
      "nct_id": "NCT06618157",
      "title": "Connectomic Guided DBS for Parkinson's Disease",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson Disease",
        "Tremor",
        "Dyskinesias"
      ],
      "interventions": [
        {
          "name": "Cerebellothalamic optimized deep brain stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Pallidothalamic optimized deep brain stimulation",
          "type": "DEVICE"
        },
        {
          "name": "No deep brain stimulation",
          "type": "OTHER"
        },
        {
          "name": "Usual care deep brain stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2026-02-16",
      "completion_date": "2027-01-29",
      "has_results": false,
      "last_update_posted_date": "2026-09-03",
      "last_synced_at": "2026-09-11T20:27:03.356Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06618157"
    },
    {
      "nct_id": "NCT02924194",
      "title": "Deep Brain Stimulation of the nbM to Treat Mild Cognitive Impairment in Parkinson's Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson's Disease",
        "Mild Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "stimulation ON",
          "type": "DEVICE"
        },
        {
          "name": "stimulation OFF",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "St. Joseph's Hospital and Medical Center, Phoenix",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "50 Years to 75 Years"
      },
      "enrollment_count": 3,
      "start_date": "2016-09",
      "completion_date": "2021-04-15",
      "has_results": false,
      "last_update_posted_date": "2021-09-21",
      "last_synced_at": "2026-09-11T20:27:03.356Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02924194"
    },
    {
      "nct_id": "NCT07455760",
      "title": "Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson's Disease (PD)",
        "Essential Tremor"
      ],
      "interventions": [
        {
          "name": "Phoneme sequence learning",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cessation and re-enabling of stimulation of the STN",
          "type": "OTHER"
        },
        {
          "name": "Cessation and re-enabling of stimulation of the VIM thalamic nucleus",
          "type": "OTHER"
        },
        {
          "name": "Multisyllabic sequence learning",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Boston University Charles River Campus",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2026-02-18",
      "completion_date": "2030-08",
      "has_results": false,
      "last_update_posted_date": "2026-03-09",
      "last_synced_at": "2026-09-11T20:27:03.356Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07455760"
    },
    {
      "nct_id": "NCT05933681",
      "title": "Neurophysiology Biomarkers of Cognitive Impairment Associated With Deep Brain Stimulation",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson Disease"
      ],
      "interventions": [
        {
          "name": "Neural recordings and stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2023-07-06",
      "completion_date": "2027-05",
      "has_results": false,
      "last_update_posted_date": "2026-06-12",
      "last_synced_at": "2026-09-11T20:27:03.356Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05933681"
    },
    {
      "nct_id": "NCT02549859",
      "title": "Long-term Effect of Low Frequency Stimulation on Aspiration and Freezing of Gait in PD With STN DBS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson's Disease"
      ],
      "interventions": [
        {
          "name": "Deep Brain Stimulation (DBS) at 60 Hz",
          "type": "DEVICE"
        },
        {
          "name": "Deep Brain Stimulation (DBS) at 130 Hz",
          "type": "DEVICE"
        },
        {
          "name": "Deep Brain Stimulation (DBS) Off (Sham)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "45 Years to 75 Years"
      },
      "enrollment_count": 11,
      "start_date": "2015-08",
      "completion_date": "2017-05",
      "has_results": true,
      "last_update_posted_date": "2020-10-29",
      "last_synced_at": "2026-09-11T20:27:03.356Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02549859"
    },
    {
      "nct_id": "NCT07594795",
      "title": "Temporal Interference Methods for Non-invasive Deep Brain Stimulation, Study 1.3",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Temporal Interference (TI) Electrical Stimulation - dACC 20 Hz TI Active",
          "type": "DEVICE"
        },
        {
          "name": "Temporal Interference (TI) Electrical Stimulation - dACC 20 Hz TI Sham",
          "type": "DEVICE"
        },
        {
          "name": "Temporal Interference (TI) Electrical Stimulation - dACC Comparison Frequency TI Active",
          "type": "DEVICE"
        },
        {
          "name": "Temporal Interference (TI) Electrical Stimulation - dACC Comparison Frequency TI Sham",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 30,
      "start_date": "2026-07-16",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-09-11",
      "last_synced_at": "2026-09-11T20:27:03.356Z",
      "location_count": 1,
      "location_summary": "Bloomington, Indiana",
      "locations": [
        {
          "city": "Bloomington",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07594795"
    },
    {
      "nct_id": "NCT04383665",
      "title": "Low Frequency Subthalamic Nucleus Deep Brain Stimulation to Improve Verbal Fluency",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson Disease"
      ],
      "interventions": [
        {
          "name": "STN DBS 10Hz",
          "type": "DEVICE"
        },
        {
          "name": "STN DBS 130Hz",
          "type": "DEVICE"
        },
        {
          "name": "STN DBS off",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2020-01-31",
      "completion_date": "2020-03-03",
      "has_results": true,
      "last_update_posted_date": "2021-07-15",
      "last_synced_at": "2026-09-11T20:27:03.356Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04383665"
    },
    {
      "nct_id": "NCT01169324",
      "title": "Effect of Deep Brain Stimulation (DBS) on Sleep Architecture in Patients With Movement Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson's Disease",
        "Tremor",
        "Dystonia"
      ],
      "interventions": [
        {
          "name": "Alteration of DBS stimulator settings",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 17,
      "start_date": "2010-07-15",
      "completion_date": "2015-12-11",
      "has_results": false,
      "last_update_posted_date": "2019-04-26",
      "last_synced_at": "2026-09-11T20:27:03.356Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01169324"
    },
    {
      "nct_id": "NCT05070013",
      "title": "Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease (Aim 2)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson's Disease",
        "Sleep Fragmentation"
      ],
      "interventions": [
        {
          "name": "Deep Brain Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 20,
      "start_date": "2021-11-18",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-07-22",
      "last_synced_at": "2026-09-11T20:27:03.356Z",
      "location_count": 2,
      "location_summary": "Omaha, Nebraska • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05070013"
    }
  ]
}