{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=DHEA+replacement",
    "query": {
      "intervention": "DHEA replacement"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 5,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T09:53:01.534Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06472765",
      "title": "Vaginal Ecosystem and Network in the United States Study",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bacterial Vaginosis",
        "Candidiasis",
        "Urinary Tract Infections",
        "Genitourinary Syndrome of Menopause",
        "Lichen Sclerosus",
        "Lichen Planus",
        "Vulvodynia",
        "Endometriosis",
        "Ureaplasma Infections",
        "Cancer",
        "Desquamative Inflammatory Vaginitis"
      ],
      "interventions": [
        {
          "name": "Vaginal Swab Collection",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Vaginal Biome Science",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 89 Years · Female only"
      },
      "enrollment_count": 3250,
      "start_date": "2024-05-16",
      "completion_date": "2028-05-15",
      "has_results": false,
      "last_update_posted_date": "2025-07-01",
      "last_synced_at": "2026-09-03T09:53:01.534Z",
      "location_count": 20,
      "location_summary": "Fullerton, California • Los Angeles, California • Pasadena, California + 16 more",
      "locations": [
        {
          "city": "Fullerton",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Pasadena",
          "state": "California"
        },
        {
          "city": "Honolulu",
          "state": "Hawaii"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06472765"
    },
    {
      "nct_id": "NCT00279929",
      "title": "DHEA Replacement in Adrenalectomized/Hypoadrenal Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging",
        "Dehydroepiandosterone Replacement",
        "DHEA Replacement"
      ],
      "interventions": [
        {
          "name": "DHEA Replacement",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 75 Years · Female only"
      },
      "enrollment_count": 32,
      "start_date": "2002-07",
      "completion_date": "2007-06",
      "has_results": false,
      "last_update_posted_date": "2011-05-23",
      "last_synced_at": "2026-09-03T09:53:01.534Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00279929"
    },
    {
      "nct_id": "NCT00182975",
      "title": "Effects of Dehydroepiandrosterone (DHEA) in Humans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Aging"
      ],
      "interventions": [
        {
          "name": "DHEA replacement",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute on Aging (NIA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "65 Years to 75 Years"
      },
      "enrollment_count": 142,
      "start_date": "2002-09",
      "completion_date": "2007-09",
      "has_results": false,
      "last_update_posted_date": "2008-08-25",
      "last_synced_at": "2026-09-03T09:53:01.534Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00182975"
    },
    {
      "nct_id": "NCT00254371",
      "title": "DHEA and Testosterone Replacement in Elderly",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging",
        "Low DHEA for Women",
        "Low Testosterone and DHEA for Men"
      ],
      "interventions": [
        {
          "name": "Androgen Replacement",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "1998-07",
      "completion_date": "2007-02",
      "has_results": false,
      "last_update_posted_date": "2011-05-23",
      "last_synced_at": "2026-09-03T09:53:01.534Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00254371"
    },
    {
      "nct_id": "NCT00310791",
      "title": "Adrenal and Gonadal Hormone Replacement in Anorexia Nervosa",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Anorexia Nervosa"
      ],
      "interventions": [
        {
          "name": "Hormone replacement therapy (estrogen/progestin)",
          "type": "DRUG"
        },
        {
          "name": "Placebo (Sugar Pill)",
          "type": "OTHER"
        },
        {
          "name": "Dehydroepiandrosterone (DHEA)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "30 Years",
        "sex": "FEMALE",
        "summary": "15 Years to 30 Years · Female only"
      },
      "enrollment_count": 80,
      "start_date": "2004-04",
      "completion_date": "2010-12",
      "has_results": true,
      "last_update_posted_date": "2018-04-11",
      "last_synced_at": "2026-09-03T09:53:01.534Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00310791"
    }
  ]
}