{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=DU-176b", "query": { "intervention": "DU-176b" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-02T11:09:15.536Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02073682", "title": "Cancer Venous Thromboembolism (VTE)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Venous Thromboembolism (VTE)", "Deep Vein Thrombosis (DVT)", "Pulmonary Embolism (PE)", "Cancer" ], "interventions": [ { "name": "Edoxaban", "type": "DRUG" }, { "name": "Dalteparin", "type": "DRUG" }, { "name": "Low molecular weight heparin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1046, "start_date": "2015-07-16", "completion_date": "2017-09-15", "has_results": true, "last_update_posted_date": "2019-03-06", "last_synced_at": "2026-09-02T11:09:15.536Z", "location_count": 4, "location_summary": "Brandon, Florida • Jonesboro, Georgia • Detroit, Michigan + 1 more", "locations": [ { "city": "Brandon", "state": "Florida" }, { "city": "Jonesboro", "state": "Georgia" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Norfolk", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02073682" }, { "nct_id": "NCT00781391", "title": "Global Study to Assess the Safety and Effectiveness of Edoxaban (DU-176b) vs Standard Practice of Dosing With Warfarin in Patients With Atrial Fibrillation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Stroke", "Atrial Fibrillation", "Embolism" ], "interventions": [ { "name": "warfarin tablets", "type": "DRUG" }, { "name": "Edoxaban tablets (high dose regimen-60mg)", "type": "DRUG" }, { "name": "Edoxaban tablets (low dose regimen-30mg)", "type": "DRUG" }, { "name": "placebo warfarin", "type": "DRUG" }, { "name": "placebo edoxaban", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 21105, "start_date": "2008-11", "completion_date": "2013-05", "has_results": true, "last_update_posted_date": "2019-03-05", "last_synced_at": "2026-09-02T11:09:15.536Z", "location_count": 316, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Gilbert, Arizona + 308 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Gilbert", "state": "Arizona" }, { "city": "Glendale", "state": "Arizona" }, { "city": "Lake Havasu City", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00781391" }, { "nct_id": "NCT02072434", "title": "Edoxaban vs. Warfarin in Subjects Undergoing Cardioversion of Nonvalvular Atrial Fibrillation (NVAF)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Atrial Fibrillation" ], "interventions": [ { "name": "Edoxaban", "type": "DRUG" }, { "name": "Warfarin", "type": "DRUG" }, { "name": "Enoxaparin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2199, "start_date": "2014-03-25", "completion_date": "2016-02-03", "has_results": true, "last_update_posted_date": "2019-03-15", "last_synced_at": "2026-09-02T11:09:15.536Z", "location_count": 28, "location_summary": "Phoenix, Arizona • Escondido, California • Newport Beach, California + 25 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Escondido", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "Riverside", "state": "California" }, { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02072434" }, { "nct_id": "NCT01662908", "title": "A Randomized, Open-Label, Parallel-Group, Multi-Center Study for the Evaluation of Efficacy and Safety of Edoxaban Monotherapy Versus Low Molecular Weight (LMW) Heparin/Warfarin in Subjects With Symptomatic Deep-Vein Thrombosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Deep Vein Thrombosis", "Venous Thrombosis" ], "interventions": [ { "name": "edoxaban tosylate", "type": "DRUG" }, { "name": "enoxaparin/unfractionated heparin", "type": "DRUG" }, { "name": "warfarin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 85, "start_date": "2012-08", "completion_date": "2014-03", "has_results": true, "last_update_posted_date": "2019-02-26", "last_synced_at": "2026-09-02T11:09:15.536Z", "location_count": 29, "location_summary": "Dothan, Alabama • Montgomery, Alabama • Sacramento, California + 26 more", "locations": [ { "city": "Dothan", "state": "Alabama" }, { "city": "Montgomery", "state": "Alabama" }, { "city": "Sacramento", "state": "California" }, { "city": "Atlantis", "state": "Florida" }, { "city": "Clearwater", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01662908" }, { "nct_id": "NCT03395639", "title": "Edoxaban for Prevention of Blood Vessels Being Blocked by Clots (Thrombotic Events) in Children at Risk Because of Cardiac Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Cardiac Disease" ], "interventions": [ { "name": "Edoxaban", "type": "DRUG" }, { "name": "Standard of Care (SOC)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Day", "maximum_age": "17 Years", "sex": "ALL", "summary": "1 Day to 17 Years" }, "enrollment_count": 168, "start_date": "2018-05-15", "completion_date": "2021-12-03", "has_results": true, "last_update_posted_date": "2022-07-26", "last_synced_at": "2026-09-02T11:09:15.536Z", "location_count": 14, "location_summary": "Birmingham, Alabama • Mesa, Arizona • Los Angeles, California + 10 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03395639" }, { "nct_id": "NCT00398216", "title": "A Study of DU-176b in Preventing Blood Clots After Hip Replacement Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Thrombosis", "Hip Replacement" ], "interventions": [ { "name": "DU176b - action is the prevention of venous thromboembolism by the use of a Factor Xa inhibitor", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 903, "start_date": "2006-05", "completion_date": "2007-06", "has_results": true, "last_update_posted_date": "2019-02-26", "last_synced_at": "2026-09-02T11:09:15.536Z", "location_count": 3, "location_summary": "Hartford, Connecticut • Sarasota, Florida • Austin, Texas", "locations": [ { "city": "Hartford", "state": "Connecticut" }, { "city": "Sarasota", "state": "Florida" }, { "city": "Austin", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00398216" }, { "nct_id": "NCT00107900", "title": "Study of the Efficacy and Safety of DU-176b in Preventing Blood Clots in Patients Undergoing Total Hip Replacement", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Arthroplasty, Replacement, Hip", "Thrombosis" ], "interventions": [ { "name": "DU-176b", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 606, "start_date": "2005-01", "completion_date": "2005-12", "has_results": true, "last_update_posted_date": "2019-02-26", "last_synced_at": "2026-09-02T11:09:15.536Z", "location_count": 1, "location_summary": "Decatur, Georgia", "locations": [ { "city": "Decatur", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00107900" }, { "nct_id": "NCT02448901", "title": "Influence of Edoxaban on Coagulability and Thrombin Generation: An in Vitro Study Focusing on Thrombelastography", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Heart Failure" ], "interventions": [ { "name": "Edoxaban", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "LifeBridge Health", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 40, "start_date": "2015-04", "completion_date": "2016-03", "has_results": false, "last_update_posted_date": "2015-05-20", "last_synced_at": "2026-09-02T11:09:15.536Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT02448901" }, { "nct_id": "NCT00986154", "title": "Comparative Investigation of Low Molecular Weight (LMW) Heparin/Edoxaban Tosylate (DU176b) Versus (LMW) Heparin/Warfarin in the Treatment of Symptomatic Deep-Vein Blood Clots and/or Lung Blood Clots. (The Edoxaban Hokusai-VTE Study).", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Venous Thromboembolism", "Deep Vein Thrombosis (DVT)", "Pulmonary Embolism (PE)", "Thromboembolism", "Venous Thrombosis" ], "interventions": [ { "name": "edoxaban tosylate(DU-176b)", "type": "DRUG" }, { "name": "low molecular weight heparin/unfractionated heparin", "type": "DRUG" }, { "name": "warfarin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 8292, "start_date": "2009-10", "completion_date": "2013-04", "has_results": true, "last_update_posted_date": "2019-03-05", "last_synced_at": "2026-09-02T11:09:15.536Z", "location_count": 82, "location_summary": "Mobile, Alabama • Montgomery, Alabama • Phoenix, Arizona + 71 more", "locations": [ { "city": "Mobile", "state": "Alabama" }, { "city": "Montgomery", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Anaheim", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00986154" }, { "nct_id": "NCT00504556", "title": "A Study to Assess the Safety of a Potential New Drug in Comparison to the Standard Practice of Dosing With Warfarin for Non-valvular Atrial Fibrillation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Atrial Fibrillation", "Thromboembolism" ], "interventions": [ { "name": "Edoxaban (DU-176b)", "type": "DRUG" }, { "name": "warfarin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 1146, "start_date": "2007-06", "completion_date": "2008-06", "has_results": true, "last_update_posted_date": "2019-02-26", "last_synced_at": "2026-09-02T11:09:15.536Z", "location_count": 22, "location_summary": "Huntsville, Alabama • Anaheim, California • Beverly Hills, California + 19 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Anaheim", "state": "California" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Stockton", "state": "California" }, { "city": "Orlando", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00504556" } ] }