{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Dental+local+anesthesia",
    "query": {
      "intervention": "Dental local anesthesia"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 65,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Dental+local+anesthesia&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-24T14:04:28.911Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07602686",
      "title": "MRI and Local Anesthesia",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Anesthesia"
      ],
      "interventions": [
        {
          "name": "ddMRI",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 102,
      "start_date": "2026-12-15",
      "completion_date": "2029-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-09-10",
      "last_synced_at": "2026-09-24T14:04:28.911Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07602686"
    },
    {
      "nct_id": "NCT05335070",
      "title": "Reducing Pain From Wisdom Molar Extractions",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Pain"
      ],
      "interventions": [
        {
          "name": "Temporo-masseteric Nerve Block",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 20,
      "start_date": "2022-09-13",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-12-05",
      "last_synced_at": "2026-09-24T14:04:28.911Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05335070"
    },
    {
      "nct_id": "NCT07584915",
      "title": "Pilot Study on EXPAREL as an Intra-articular Posteromedial Surgeon Administered (IPSA) Block vs. Local Infiltration Analgesia in Knee Replacement Surgery",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Total Knee Arthroplasty",
        "Total Knee Arthroplasty Recovery"
      ],
      "interventions": [
        {
          "name": "Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA",
          "type": "PROCEDURE"
        },
        {
          "name": "Local Infiltration Analgesia (LIA)",
          "type": "PROCEDURE"
        },
        {
          "name": "Bupivacaine liposome injectable suspension (IPSA block)",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine liposome injectable suspension (LIA)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2026-06-01",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2026-05-13",
      "last_synced_at": "2026-09-24T14:04:28.911Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07584915"
    },
    {
      "nct_id": "NCT00574015",
      "title": "The Comparison of Supraperiosteal Nerve Block With Opiate Analgesia in Alleviating the Pain of Toothache",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Toothache"
      ],
      "interventions": [
        {
          "name": "hydrocodone/acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "bupivacaine (supraperiosteal nerve block)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Albany Medical College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 18,
      "start_date": "2007-12",
      "completion_date": "2013-01",
      "has_results": false,
      "last_update_posted_date": "2014-03-24",
      "last_synced_at": "2026-09-24T14:04:28.911Z",
      "location_count": 1,
      "location_summary": "Albany, New York",
      "locations": [
        {
          "city": "Albany",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00574015"
    },
    {
      "nct_id": "NCT04979338",
      "title": "Development of Effective, Opioid Sparing Techniques for Peri-operative Pain Management of Transgender Patients Undergoing Gender Affirming Surgeries",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Gender Dysphoria"
      ],
      "interventions": [
        {
          "name": "Ultrasound guided Continuous Infraclavicular Brachial Plexus Block",
          "type": "OTHER"
        },
        {
          "name": "Ultrasound guided Continuous Femoral Nerve Block",
          "type": "OTHER"
        },
        {
          "name": "Ultrasound guided Pudendal Nerve Block",
          "type": "OTHER"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Bilateral ultrasound guided Transversus Abdominis Plane Block",
          "type": "OTHER"
        },
        {
          "name": "Bilateral spermatic cord block",
          "type": "OTHER"
        },
        {
          "name": "Pecs I & II Block",
          "type": "OTHER"
        },
        {
          "name": "Local anesthetic",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 640,
      "start_date": "2021-11-11",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-09-17",
      "last_synced_at": "2026-09-24T14:04:28.911Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04979338"
    },
    {
      "nct_id": "NCT01944267",
      "title": "Procedures for Improving the Mucosa Around Implants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Keratinized Mucosa",
        "Dental Implants"
      ],
      "interventions": [
        {
          "name": "Apically positioned flap",
          "type": "PROCEDURE"
        },
        {
          "name": "Free Gingival Graft",
          "type": "PROCEDURE"
        },
        {
          "name": "apically positioned flap with Mucograft",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 30,
      "start_date": "2013-10",
      "completion_date": "2016-05",
      "has_results": false,
      "last_update_posted_date": "2018-09-24",
      "last_synced_at": "2026-09-24T14:04:28.911Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01944267"
    },
    {
      "nct_id": "NCT01808703",
      "title": "Clinical Trial of PeriZone PerioPatch in Subjects With Chronic Periodontitis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Periodontitis"
      ],
      "interventions": [
        {
          "name": "PeriZone PerioPatch",
          "type": "DEVICE"
        },
        {
          "name": "Scaling and root planing alone",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "MIS Implant Technologies, Ltd",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2013-03",
      "completion_date": "2013-09",
      "has_results": false,
      "last_update_posted_date": "2013-03-11",
      "last_synced_at": "2026-09-24T14:04:28.911Z",
      "location_count": 2,
      "location_summary": "Chapel Hill, North Carolina • Norfolk, Virginia",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01808703"
    },
    {
      "nct_id": "NCT02572570",
      "title": "Clinical Investigation of a New Bulk Fill Composite Resin in the Restoration of Posterior Teeth",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Restoration Failure of Marginal Integrity",
        "Dental Caries",
        "Unrepairable Overhanging of Dental Restorative Materials",
        "Poor Aesthetics of Existing Restoration",
        "Secondary Dental Caries Associated With Failed or Defective Dental Restorations",
        "Fractured Dental Restorative Materials Without Loss of Materials",
        "Fracture of Dental Restorative Materials With Loss of Material"
      ],
      "interventions": [
        {
          "name": "Filtek Bulk Fill Posterior",
          "type": "DEVICE"
        },
        {
          "name": "Filtek Supreme Ultra",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 27,
      "start_date": "2015-12",
      "completion_date": "2019-12-05",
      "has_results": true,
      "last_update_posted_date": "2020-12-19",
      "last_synced_at": "2026-09-24T14:04:28.911Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02572570"
    },
    {
      "nct_id": "NCT04787731",
      "title": "Efficacy of Two Local Anesthetics on Quality of Life After Endodontic Treatment",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain, Postoperative",
        "Quality of Life"
      ],
      "interventions": [
        {
          "name": "Bupivacaine Local Anesthetic",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NYU College of Dentistry",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 100,
      "start_date": "2019-07-29",
      "completion_date": "2024-10-01",
      "has_results": false,
      "last_update_posted_date": "2023-11-08",
      "last_synced_at": "2026-09-24T14:04:28.911Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04787731"
    },
    {
      "nct_id": "NCT04822233",
      "title": "A Comparative Study of Hall Technique, Modified Hall Technique and Conventional Stainless-Steel Crown Restorations in the Treatment of Primary Molars With Proximal Caries Lesions.",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Hall Technique (HT)",
          "type": "DEVICE"
        },
        {
          "name": "Modified Hall Technique (MHT)",
          "type": "DEVICE"
        },
        {
          "name": "Conventional Technique (CT)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "8 Years",
        "sex": "ALL",
        "summary": "5 Years to 8 Years"
      },
      "enrollment_count": 132,
      "start_date": "2023-06-01",
      "completion_date": "2025-12-01",
      "has_results": false,
      "last_update_posted_date": "2023-05-19",
      "last_synced_at": "2026-09-24T14:04:28.911Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04822233"
    }
  ]
}