{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Dental+local+anesthesia&page=2",
    "query": {
      "intervention": "Dental local anesthesia",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 65,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Dental+local+anesthesia&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Dental+local+anesthesia&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-02T09:18:07.895Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07468929",
      "title": "Serum Inflammatory Protein Concentration During Dental Treatment",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Periodontal Disease",
        "Periodontal Surgery"
      ],
      "interventions": [
        {
          "name": "Blood samples for inflammatory markers",
          "type": "OTHER"
        },
        {
          "name": "periodontal surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Periodontal maintenance",
          "type": "PROCEDURE"
        },
        {
          "name": "Non-surgical deep cleaning",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 30,
      "start_date": "2026-07-13",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-09-11",
      "last_synced_at": "2026-10-02T09:18:07.895Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07468929"
    },
    {
      "nct_id": "NCT06309693",
      "title": "Postoperative Pain Management Following Robotic Assisted Sacrocolpopexy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pelvic Organ Prolapse",
        "Post Operative Pain"
      ],
      "interventions": [
        {
          "name": "Quadratus Lumborum (QL) Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Enhanced Recovery After Surgical (ERAS) Protocol",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 70,
      "start_date": "2025-01-22",
      "completion_date": "2026-01-09",
      "has_results": false,
      "last_update_posted_date": "2026-01-12",
      "last_synced_at": "2026-10-02T09:18:07.895Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06309693"
    },
    {
      "nct_id": "NCT05684068",
      "title": "Dimensional Changes: Randomized Clinical Trial",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingival Recession"
      ],
      "interventions": [
        {
          "name": "Gum Graft Placed on Denuded Bone",
          "type": "PROCEDURE"
        },
        {
          "name": "Gum Graft Placed on Split Thickness Periosteal Bed Preparation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "18 Years to 95 Years"
      },
      "enrollment_count": 50,
      "start_date": "2028-08",
      "completion_date": "2031-03",
      "has_results": false,
      "last_update_posted_date": "2026-09-09",
      "last_synced_at": "2026-10-02T09:18:07.895Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05684068"
    },
    {
      "nct_id": "NCT01808703",
      "title": "Clinical Trial of PeriZone PerioPatch in Subjects With Chronic Periodontitis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Periodontitis"
      ],
      "interventions": [
        {
          "name": "PeriZone PerioPatch",
          "type": "DEVICE"
        },
        {
          "name": "Scaling and root planing alone",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "MIS Implant Technologies, Ltd",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2013-03",
      "completion_date": "2013-09",
      "has_results": false,
      "last_update_posted_date": "2013-03-11",
      "last_synced_at": "2026-10-02T09:18:07.895Z",
      "location_count": 2,
      "location_summary": "Chapel Hill, North Carolina • Norfolk, Virginia",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01808703"
    },
    {
      "nct_id": "NCT06058533",
      "title": "Pre-Visit Positive Imagery in Reducing Dental Anxiety",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Anxiety"
      ],
      "interventions": [
        {
          "name": "Previsit Imagery Picturebook",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "10 Years",
        "sex": "ALL",
        "summary": "4 Years to 10 Years"
      },
      "enrollment_count": 55,
      "start_date": "2023-10-15",
      "completion_date": "2025-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-07-14",
      "last_synced_at": "2026-10-02T09:18:07.895Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06058533"
    },
    {
      "nct_id": "NCT02572570",
      "title": "Clinical Investigation of a New Bulk Fill Composite Resin in the Restoration of Posterior Teeth",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Restoration Failure of Marginal Integrity",
        "Dental Caries",
        "Unrepairable Overhanging of Dental Restorative Materials",
        "Poor Aesthetics of Existing Restoration",
        "Secondary Dental Caries Associated With Failed or Defective Dental Restorations",
        "Fractured Dental Restorative Materials Without Loss of Materials",
        "Fracture of Dental Restorative Materials With Loss of Material"
      ],
      "interventions": [
        {
          "name": "Filtek Bulk Fill Posterior",
          "type": "DEVICE"
        },
        {
          "name": "Filtek Supreme Ultra",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 27,
      "start_date": "2015-12",
      "completion_date": "2019-12-05",
      "has_results": true,
      "last_update_posted_date": "2020-12-19",
      "last_synced_at": "2026-10-02T09:18:07.895Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02572570"
    },
    {
      "nct_id": "NCT01622296",
      "title": "Comparison of Pain of Conventional to Buffered Local Anesthesia During Injection in Pediatric Dental Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Sodium bicarbonate",
          "type": "DRUG"
        },
        {
          "name": "Lidocaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "9 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "9 Years to 12 Years"
      },
      "enrollment_count": 20,
      "start_date": "2012-04",
      "completion_date": "2013-07",
      "has_results": true,
      "last_update_posted_date": "2014-03-17",
      "last_synced_at": "2026-10-02T09:18:07.895Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01622296"
    },
    {
      "nct_id": "NCT01934530",
      "title": "A Randomized Control Trial Testing Connective Tissue Grafts vs. Allograft on Dental Implants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Implant Soft Tissue Defects in the Anterior Maxilla"
      ],
      "interventions": [
        {
          "name": "Soft Tissue Grafting",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 13,
      "start_date": "2009-08",
      "completion_date": "2012-07",
      "has_results": false,
      "last_update_posted_date": "2017-02-10",
      "last_synced_at": "2026-10-02T09:18:07.895Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01934530"
    },
    {
      "nct_id": "NCT02579187",
      "title": "MicroRNA and MicroRNA Inhibitors Socket Study, Pilot Clinical Trial",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Tooth Extraction Status Nos"
      ],
      "interventions": [
        {
          "name": "tooth extraction",
          "type": "PROCEDURE"
        },
        {
          "name": "CBCT scan",
          "type": "RADIATION"
        },
        {
          "name": "Anesthesia",
          "type": "DRUG"
        },
        {
          "name": "clinical measurements",
          "type": "OTHER"
        },
        {
          "name": "Biodegradable sponge (type I bovine collagen)",
          "type": "DRUG"
        },
        {
          "name": "10µg of pSil-miR200c",
          "type": "DRUG"
        },
        {
          "name": "cross mattress suture",
          "type": "PROCEDURE"
        },
        {
          "name": "10µg of PMIS miR200a plasmids",
          "type": "DRUG"
        },
        {
          "name": "5µg of pSil-miR200c and 5µg of PMIS miR200a",
          "type": "DRUG"
        },
        {
          "name": "Blood",
          "type": "PROCEDURE"
        },
        {
          "name": "Photos/videos",
          "type": "OTHER"
        },
        {
          "name": "Wound fluid",
          "type": "PROCEDURE"
        },
        {
          "name": "saliva",
          "type": "PROCEDURE"
        },
        {
          "name": "periapical xray",
          "type": "RADIATION"
        },
        {
          "name": "PVS impression",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "RADIATION",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Gustavo Avila-Ortiz DDS, MS, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "25 Years to 65 Years"
      },
      "enrollment_count": 0,
      "start_date": "2025-12-31",
      "completion_date": "2030-09",
      "has_results": false,
      "last_update_posted_date": "2019-07-17",
      "last_synced_at": "2026-10-02T09:18:07.895Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02579187"
    },
    {
      "nct_id": "NCT00937976",
      "title": "Treatment for Periodontal Disease in Dialysis Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periodontal Disease"
      ],
      "interventions": [
        {
          "name": "Periodontal Scaling and Root Planing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 60,
      "start_date": "2008-08",
      "completion_date": "2010-06",
      "has_results": false,
      "last_update_posted_date": "2012-05-07",
      "last_synced_at": "2026-10-02T09:18:07.895Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00937976"
    }
  ]
}