{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Depression%2C+adjusted", "query": { "intervention": "Depression, adjusted" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 86, "total_pages": 9, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Depression%2C+adjusted&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-06T03:02:24.126Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06502483", "title": "PRISM for Depression and Anxiety in Young Adults With Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cancer Diagnosis", "Non-Metastatic Neoplasm", "Anxiety", "Anxiety Disorders", "Depression", "Depressive Disorder", "Depression, Anxiety", "Desmoid" ], "interventions": [ { "name": "Promoting Resilience in Stress Management Program", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Dana-Farber Cancer Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "39 Years", "sex": "ALL", "summary": "18 Years to 39 Years" }, "enrollment_count": 13, "start_date": "2024-09-06", "completion_date": "2026-02-01", "has_results": false, "last_update_posted_date": "2026-04-21", "last_synced_at": "2026-09-06T03:02:24.126Z", "location_count": 1, "location_summary": "Brighton, Massachusetts", "locations": [ { "city": "Brighton", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT06502483" }, { "nct_id": "NCT00723476", "title": "Family Centered Advanced Care Planning for Adolescents With HIV/AIDS and Their Families", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "HIV Infections" ], "interventions": [ { "name": "Family Centered Advanced Care Planning (FCACP) sessions", "type": "BEHAVIORAL" }, { "name": "Health education control sessions", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Maureen Lyon", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 82, "start_date": "2005-09", "completion_date": "2008-09", "has_results": false, "last_update_posted_date": "2015-05-21", "last_synced_at": "2026-09-06T03:02:24.126Z", "location_count": 1, "location_summary": "Washington D.C., District of Columbia", "locations": [ { "city": "Washington D.C.", "state": "District of Columbia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00723476" }, { "nct_id": "NCT01032018", "title": "Comparison of Depression Interventions After Acute Coronary Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Acute Coronary Syndrome", "Depression" ], "interventions": [ { "name": "Problem Solving Therapy", "type": "BEHAVIORAL" }, { "name": "Sertraline, citalopram, or bupropion", "type": "DRUG" }, { "name": "Standard care", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "DRUG", "OTHER" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "35 Years", "maximum_age": null, "sex": "ALL", "summary": "35 Years and older" }, "enrollment_count": 150, "start_date": "2010-01", "completion_date": "2012-07", "has_results": true, "last_update_posted_date": "2017-09-13", "last_synced_at": "2026-09-06T03:02:24.126Z", "location_count": 5, "location_summary": "New Haven, Connecticut • Atlanta, Georgia • St Louis, Missouri + 2 more", "locations": [ { "city": "New Haven", "state": "Connecticut" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "St Louis", "state": "Missouri" }, { "city": "New York", "state": "New York" }, { "city": "Yardley", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01032018" }, { "nct_id": "NCT02044211", "title": "Blended Collaborative Care for Heart Failure and Co-Morbid Depression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Heart Failure, Systolic", "Depression", "Cardiovascular Disease" ], "interventions": [ { "name": "Collaborative Care for Heart Failure", "type": "BEHAVIORAL" }, { "name": "Collaborative Care for Depression", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Pittsburgh", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 756, "start_date": "2014-02", "completion_date": "2020-07", "has_results": false, "last_update_posted_date": "2020-08-05", "last_synced_at": "2026-09-06T03:02:24.126Z", "location_count": 1, "location_summary": "Pittsburgh, Pennsylvania", "locations": [ { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02044211" }, { "nct_id": "NCT04513912", "title": "A Study of Seltorexant Compared to Quetiapine XR as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Depressive Disorder, Major" ], "interventions": [ { "name": "Seltorexant", "type": "DRUG" }, { "name": "Matching placebo to Seltorexant", "type": "DRUG" }, { "name": "Quetiapine XR", "type": "DRUG" }, { "name": "Matching placebo to Quetiapine XR", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "74 Years", "sex": "ALL", "summary": "18 Years to 74 Years" }, "enrollment_count": 757, "start_date": "2020-09-15", "completion_date": "2023-10-03", "has_results": false, "last_update_posted_date": "2025-08-13", "last_synced_at": "2026-09-06T03:02:24.126Z", "location_count": 75, "location_summary": "Birmingham, Alabama • Tucson, Arizona • Culver City, California + 62 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Culver City", "state": "California" }, { "city": "Encino", "state": "California" }, { "city": "Garden Grove", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04513912" }, { "nct_id": "NCT00411463", "title": "Psychotherapy for Bipolar II Depression, Pilot Study, Phase II", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Bipolar II Disorder" ], "interventions": [ { "name": "Interpersonal and Social Rhythm Therapy (IPSRT-BPII)", "type": "BEHAVIORAL" }, { "name": "Seroquel", "type": "DRUG" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "University of Pittsburgh", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 25, "start_date": "2006-12", "completion_date": "2010-09", "has_results": true, "last_update_posted_date": "2017-05-30", "last_synced_at": "2026-09-06T03:02:24.126Z", "location_count": 1, "location_summary": "Pittsburgh, Pennsylvania", "locations": [ { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00411463" }, { "nct_id": "NCT05755165", "title": "Adolescent Depression: Video Ads on Instagram", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Depression", "Stigmatization" ], "interventions": [ { "name": "Depression", "type": "BEHAVIORAL" }, { "name": "Depression, adjusted", "type": "BEHAVIORAL" }, { "name": "Control", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "14 Years", "maximum_age": "18 Years", "sex": "ALL", "summary": "14 Years to 18 Years" }, "enrollment_count": 1235, "start_date": "2024-08-01", "completion_date": "2024-09-01", "has_results": false, "last_update_posted_date": "2024-11-08", "last_synced_at": "2026-09-06T03:02:24.126Z", "location_count": 2, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" }, { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT05755165" }, { "nct_id": "NCT07413705", "title": "BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Depressive Symptoms", "Urinary Incontinence", "Sexual Dysfunction" ], "interventions": [ { "name": "EXOMIND (BTL-699-2) Active Treatment", "type": "DEVICE" }, { "name": "EMSELLA (HPM-6000UF) ActiveTreatment", "type": "DEVICE" }, { "name": "EXOMIND (BTL-699-2) Sham Treatment", "type": "DEVICE" }, { "name": "EMSELLA (HPM-6000UF) Sham Treatment", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "BTL Industries Ltd.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "FEMALE", "summary": "40 Years and older · Female only" }, "enrollment_count": 60, "start_date": "2025-11-20", "completion_date": "2026-12-11", "has_results": false, "last_update_posted_date": "2026-02-17", "last_synced_at": "2026-09-06T03:02:24.126Z", "location_count": 2, "location_summary": "Winter Garden, Florida • Wellesley, Massachusetts", "locations": [ { "city": "Winter Garden", "state": "Florida" }, { "city": "Wellesley", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT07413705" }, { "nct_id": "NCT00091962", "title": "Effectiveness of Depression Treatment Following Coronary Artery Bypass Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cardiovascular Diseases", "Coronary Disease", "Heart Diseases", "Depression" ], "interventions": [ { "name": "Psychoeducation; Treatment recommendations", "type": "BEHAVIORAL" }, { "name": "Pharmacotherapy", "type": "DRUG" }, { "name": "Usual Care", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "DRUG", "OTHER" ], "sponsor": "University of Pittsburgh", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 453, "start_date": "2003-08", "completion_date": "2009-12", "has_results": true, "last_update_posted_date": "2016-04-14", "last_synced_at": "2026-09-06T03:02:24.126Z", "location_count": 1, "location_summary": "Pittsburgh, Pennsylvania", "locations": [ { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00091962" }, { "nct_id": "NCT01066897", "title": "Imaging the Nucleus Accumbens in Major Depressed Patients 'Treated With Pramipexole", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Depression" ], "interventions": [ { "name": "Pramipexole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Stanford University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "20 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "20 Years to 65 Years" }, "enrollment_count": 16, "start_date": "2010-02", "completion_date": "2013-02", "has_results": true, "last_update_posted_date": "2017-05-16", "last_synced_at": "2026-09-06T03:02:24.126Z", "location_count": 1, "location_summary": "Stanford, California", "locations": [ { "city": "Stanford", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01066897" } ] }