{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Depression%2C+adjusted&page=2",
    "query": {
      "intervention": "Depression, adjusted",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Depression%2C+adjusted&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-25T10:27:54.518Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06502483",
      "title": "PRISM for Depression and Anxiety in Young Adults With Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer Diagnosis",
        "Non-Metastatic Neoplasm",
        "Anxiety",
        "Anxiety Disorders",
        "Depression",
        "Depressive Disorder",
        "Depression, Anxiety",
        "Desmoid"
      ],
      "interventions": [
        {
          "name": "Promoting Resilience in Stress Management Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Dana-Farber Cancer Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 13,
      "start_date": "2024-09-06",
      "completion_date": "2026-02-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-21",
      "last_synced_at": "2026-09-25T10:27:54.518Z",
      "location_count": 1,
      "location_summary": "Brighton, Massachusetts",
      "locations": [
        {
          "city": "Brighton",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06502483"
    },
    {
      "nct_id": "NCT07018726",
      "title": "Addressing Emotional Distress in Dyads of Persons With a Young Onset Dementia (YOD) and Their Care-partners",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Young Onset Dementia"
      ],
      "interventions": [
        {
          "name": "Resilient Together-YOD",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health Enhancement Program-YOD",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 388,
      "start_date": "2026-01-28",
      "completion_date": "2031-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-15",
      "last_synced_at": "2026-09-25T10:27:54.518Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07018726"
    },
    {
      "nct_id": "NCT01566539",
      "title": "Biological Basis of Individual Variation in Social Cooperation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Intranasal Oxytocin (OT) 24 IU",
          "type": "DRUG"
        },
        {
          "name": "Intranasal Vasopressin (AVP)",
          "type": "DRUG"
        },
        {
          "name": "Intranasal Placebo",
          "type": "DRUG"
        },
        {
          "name": "Intranasal Vasopressin (AVP) 40 IU",
          "type": "DRUG"
        },
        {
          "name": "Lorazepam",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 707,
      "start_date": "2008-04",
      "completion_date": "2016-11",
      "has_results": true,
      "last_update_posted_date": "2017-09-25",
      "last_synced_at": "2026-09-25T10:27:54.518Z",
      "location_count": 2,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01566539"
    },
    {
      "nct_id": "NCT00590863",
      "title": "Combining Medications to Enhance Depression Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "SSRI + placebo",
          "type": "DRUG"
        },
        {
          "name": "Escitalopram + Bupropion SR",
          "type": "DRUG"
        },
        {
          "name": "Venlafaxine XR + Mirtazapine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 665,
      "start_date": "2008-03",
      "completion_date": "2009-09",
      "has_results": true,
      "last_update_posted_date": "2014-04-23",
      "last_synced_at": "2026-09-25T10:27:54.518Z",
      "location_count": 15,
      "location_summary": "Tuscaloosa, Alabama • Harbor City, California • Los Angeles, California + 12 more",
      "locations": [
        {
          "city": "Tuscaloosa",
          "state": "Alabama"
        },
        {
          "city": "Harbor City",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00590863"
    },
    {
      "nct_id": "NCT03680781",
      "title": "Accelerated Theta Burst in Treatment-Resistant Depression: A Dose Finding and Biomarker Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Treatment Resistant Depression"
      ],
      "interventions": [
        {
          "name": "Intermittent theta-burst stimulation (iTBS) delivered to the L-DLPFC",
          "type": "DEVICE"
        },
        {
          "name": "Intermittent theta-burst stimulation (iTBS) delivered to the bilateral DLPFC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 40,
      "start_date": "2018-04-13",
      "completion_date": "2024-12-02",
      "has_results": true,
      "last_update_posted_date": "2026-07-22",
      "last_synced_at": "2026-09-25T10:27:54.518Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03680781"
    },
    {
      "nct_id": "NCT06467695",
      "title": "Low Voltage Electrical Stimulation for Depression in Parkinson's Patients",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson Disease",
        "Depressive Symptoms"
      ],
      "interventions": [
        {
          "name": "BIOPAC Stimsola",
          "type": "DEVICE"
        },
        {
          "name": "BIOPAC Stimsola Sham (zero amps)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of South Alabama",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "19 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2024-08-01",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-06",
      "last_synced_at": "2026-09-25T10:27:54.518Z",
      "location_count": 1,
      "location_summary": "Mobile, Alabama",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06467695"
    },
    {
      "nct_id": "NCT04134754",
      "title": "Carbon Dioxide (CO2) Chemosensitivity and SUDEP",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Epilepsy",
        "SUDEP"
      ],
      "interventions": [
        {
          "name": "6% Carbon dioxide/50% oxygen/balance nitrogen mixture",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 335,
      "start_date": "2019-12-12",
      "completion_date": "2029-10-01",
      "has_results": false,
      "last_update_posted_date": "2026-06-23",
      "last_synced_at": "2026-09-25T10:27:54.518Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04134754"
    },
    {
      "nct_id": "NCT01608295",
      "title": "Vilazodone for Treatment of Geriatric Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "Vilazodone; Viibryd",
          "type": "DRUG"
        },
        {
          "name": "Paroxetine; Paxil",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2012-07",
      "completion_date": "2015-09",
      "has_results": true,
      "last_update_posted_date": "2018-05-11",
      "last_synced_at": "2026-09-25T10:27:54.518Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01608295"
    },
    {
      "nct_id": "NCT07413705",
      "title": "BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depressive Symptoms",
        "Urinary Incontinence",
        "Sexual Dysfunction"
      ],
      "interventions": [
        {
          "name": "EXOMIND (BTL-699-2) Active Treatment",
          "type": "DEVICE"
        },
        {
          "name": "EMSELLA (HPM-6000UF) ActiveTreatment",
          "type": "DEVICE"
        },
        {
          "name": "EXOMIND (BTL-699-2) Sham Treatment",
          "type": "DEVICE"
        },
        {
          "name": "EMSELLA (HPM-6000UF) Sham Treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "BTL Industries Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "40 Years and older · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2025-11-20",
      "completion_date": "2026-12-11",
      "has_results": false,
      "last_update_posted_date": "2026-02-17",
      "last_synced_at": "2026-09-25T10:27:54.518Z",
      "location_count": 2,
      "location_summary": "Winter Garden, Florida • Wellesley, Massachusetts",
      "locations": [
        {
          "city": "Winter Garden",
          "state": "Florida"
        },
        {
          "city": "Wellesley",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07413705"
    },
    {
      "nct_id": "NCT07814755",
      "title": "Auricular Vagal Neuromodulation for Depression and Anxiety in Substance Use Disorder",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Substance Use Disorder (SUD)"
      ],
      "interventions": [
        {
          "name": "Transcutaneous Auricular Vagus Nerve Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Daisy Thompson-Lake",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 50,
      "start_date": "2026-10",
      "completion_date": "2029-10",
      "has_results": false,
      "last_update_posted_date": "2026-09-11",
      "last_synced_at": "2026-09-25T10:27:54.518Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07814755"
    }
  ]
}