{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Dextromethorphan+hydrobromide&page=2", "query": { "intervention": "Dextromethorphan hydrobromide", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Dextromethorphan+hydrobromide&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-24T15:02:27.896Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01630811", "title": "Nuedexta for the Treatment of Adults With Autism", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Autism" ], "interventions": [ { "name": "Nuedexta", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Sutter Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 13, "start_date": "2012-01-24", "completion_date": "2015-12-15", "has_results": true, "last_update_posted_date": "2017-12-08", "last_synced_at": "2026-09-24T15:02:27.896Z", "location_count": 1, "location_summary": "Sacramento, California", "locations": [ { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01630811" }, { "nct_id": "NCT01367535", "title": "Effects of MNTX on CYP450 2D6 in Metabolizers of Dextromethorphan", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy Adults" ], "interventions": [ { "name": "SC Methylnaltrexone (MNTX)", "type": "DRUG" }, { "name": "IV Methylnaltrexone (MNTX)", "type": "DRUG" }, { "name": "Oral Paroxetine", "type": "DRUG" }, { "name": "SC Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bausch Health Americas, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "MALE", "summary": "18 Years to 55 Years · Male only" }, "enrollment_count": 54, "start_date": "2006-03", "completion_date": "2006-08", "has_results": false, "last_update_posted_date": "2019-11-27", "last_synced_at": "2026-09-24T15:02:27.896Z", "location_count": 1, "location_summary": "Tarrytown, New York", "locations": [ { "city": "Tarrytown", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01367535" }, { "nct_id": "NCT01462318", "title": "An Open-Label Immunogenicity and Pharmacokinetics Study of Daclizumab High Yield Process Prefilled Syringe in Relapsing Remitting Multiple Sclerosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Relapsing-Remitting Multiple Sclerosis" ], "interventions": [ { "name": "Midazolam", "type": "DRUG" }, { "name": "Caffeine", "type": "OTHER" }, { "name": "S-warfarin", "type": "DRUG" }, { "name": "Vitamin K", "type": "OTHER" }, { "name": "Omeprazole", "type": "DRUG" }, { "name": "Dextromethorphan", "type": "DRUG" }, { "name": "BIIB019 (Daclizumab)", "type": "BIOLOGICAL" } ], "intervention_types": [ "DRUG", "OTHER", "BIOLOGICAL" ], "sponsor": "Biogen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 133, "start_date": "2011-11", "completion_date": "2016-01", "has_results": true, "last_update_posted_date": "2017-03-14", "last_synced_at": "2026-09-24T15:02:27.896Z", "location_count": 7, "location_summary": "Centennial, Colorado • Washington D.C., District of Columbia • Lake Barrington, Illinois + 4 more", "locations": [ { "city": "Centennial", "state": "Colorado" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Lake Barrington", "state": "Illinois" }, { "city": "Lexington", "state": "Kentucky" }, { "city": "Farmington Hills", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT01462318" }, { "nct_id": "NCT06223880", "title": "A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "AXS-05", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Axsome Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 350, "start_date": "2023-12-27", "completion_date": "2026-03", "has_results": false, "last_update_posted_date": "2025-01-23", "last_synced_at": "2026-09-24T15:02:27.896Z", "location_count": 40, "location_summary": "Bellflower, California • Lafayette, California • Oceanside, California + 34 more", "locations": [ { "city": "Bellflower", "state": "California" }, { "city": "Lafayette", "state": "California" }, { "city": "Oceanside", "state": "California" }, { "city": "Redlands", "state": "California" }, { "city": "Riverside", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06223880" }, { "nct_id": "NCT02293096", "title": "Pharmacogenetic Prediction of Metoprolol Effectiveness", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "metoprolol succinate", "type": "DRUG" }, { "name": "Genotyping", "type": "GENETIC" }, { "name": "CYP2D6 Phenotyping", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "GENETIC", "PROCEDURE" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "30 Years to 80 Years" }, "enrollment_count": 462, "start_date": "2014-09", "completion_date": "2017-08-23", "has_results": true, "last_update_posted_date": "2021-09-16", "last_synced_at": "2026-09-24T15:02:27.896Z", "location_count": 1, "location_summary": "Aurora, Colorado", "locations": [ { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT02293096" }, { "nct_id": "NCT07766655", "title": "Studying NMDA and Sigma-1 in Smoking Cessation Treatment (SUMMIT)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Smoking Cessation" ], "interventions": [ { "name": "AXS-05 (dextromethorphan-bupropion)", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Axsome Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 705, "start_date": "2026-08-27", "completion_date": "2027-12", "has_results": false, "last_update_posted_date": "2026-09-08", "last_synced_at": "2026-09-24T15:02:27.896Z", "location_count": 16, "location_summary": "Little Rock, Arkansas • Lemon Grove, California • Pomona, California + 13 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Lemon Grove", "state": "California" }, { "city": "Pomona", "state": "California" }, { "city": "DeLand", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07766655" }, { "nct_id": "NCT04039022", "title": "Open-Label Safety Study of AXS-05 in Subjects With Depression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Major Depressive Disorder", "Treatment Resistant Depression", "Depression" ], "interventions": [ { "name": "AXS-05 (dextromethorphan and bupropion) oral tablets", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Axsome Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 876, "start_date": "2019-07-08", "completion_date": "2020-10-23", "has_results": true, "last_update_posted_date": "2022-10-12", "last_synced_at": "2026-09-24T15:02:27.896Z", "location_count": 51, "location_summary": "Phoenix, Arizona • Little Rock, Arkansas • Bellflower, California + 46 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Bellflower", "state": "California" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Culver City", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04039022" }, { "nct_id": "NCT01257542", "title": "Acute Cough Study In Children", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Common Cold", "Infections, Upper Respiratory Tract" ], "interventions": [ { "name": "Dextromethorphan", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": "11 Years", "sex": "ALL", "summary": "6 Years to 11 Years" }, "enrollment_count": 140, "start_date": "2010-12", "completion_date": "2011-03", "has_results": true, "last_update_posted_date": "2012-09-20", "last_synced_at": "2026-09-24T15:02:27.896Z", "location_count": 4, "location_summary": "Pinellas Park, Florida • Indianapolis, Indiana • Gresham, Oregon + 1 more", "locations": [ { "city": "Pinellas Park", "state": "Florida" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Gresham", "state": "Oregon" }, { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT01257542" }, { "nct_id": "NCT00021697", "title": "Safety/Efficacy of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Crying & Laughing) in Patients With ALS", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Amyotrophic Lateral Sclerosis" ], "interventions": [ { "name": "AVP-923", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Avanir Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 100, "start_date": "2001-01", "completion_date": "2002-04", "has_results": false, "last_update_posted_date": "2016-07-14", "last_synced_at": "2026-09-24T15:02:27.896Z", "location_count": 17, "location_summary": "Loma Linda, California • Los Angeles, California • San Francisco, California + 13 more", "locations": [ { "city": "Loma Linda", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00021697" }, { "nct_id": "NCT07284472", "title": "Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Agitation Associated With Alzheimer's Disease Dementia" ], "interventions": [ { "name": "EXV-802", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "EXV-801", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Exciva GmbH", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "55 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "55 Years to 90 Years" }, "enrollment_count": 300, "start_date": "2026-02-02", "completion_date": "2029-02", "has_results": false, "last_update_posted_date": "2026-08-14", "last_synced_at": "2026-09-24T15:02:27.896Z", "location_count": 9, "location_summary": "Murrieta, California • Indianapolis, Indiana • Flowood, Mississippi + 6 more", "locations": [ { "city": "Murrieta", "state": "California" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Flowood", "state": "Mississippi" }, { "city": "Chesterfield", "state": "Missouri" }, { "city": "Brooklyn", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT07284472" } ] }