{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=DiRECT&page=20", "query": { "intervention": "DiRECT", "page": 20 }, "page_size": 10 }, "pagination": { "page": 20, "page_size": 10, "total_count": 3415, "total_pages": 342, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=DiRECT&page=21&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=DiRECT&page=19&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-24T00:42:19.328Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00944931", "title": "High-Density Direct Current Brain Polarization", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy Volunteer", "HV" ], "interventions": [ { "name": "DC Brain Polarization", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "2009-07-20", "completion_date": "2011-04-05", "has_results": false, "last_update_posted_date": "2017-07-02", "last_synced_at": "2026-10-24T00:42:19.328Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00944931" }, { "nct_id": "NCT00681356", "title": "Safety and Efficacy Study of 4975 in Patients Undergoing Total Knee Replacement", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Total Knee Arthroplasty (Replacement)" ], "interventions": [ { "name": "4975, 15 and 5 mg", "type": "DRUG" }, { "name": "Placebo Comparator", "type": "DRUG" }, { "name": "4975 - 5 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Anesiva, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 214, "start_date": "2007-09", "completion_date": "2008-12", "has_results": false, "last_update_posted_date": "2009-05-04", "last_synced_at": "2026-10-24T00:42:19.328Z", "location_count": 25, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Sheffield, Alabama + 20 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Sheffield", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Glendale", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00681356" }, { "nct_id": "NCT00005739", "title": "Behavioral Interventions for Control of TB", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Lung Diseases", "Tuberculosis" ], "interventions": [ { "name": "Community-based directly observed therapy (DOT)", "type": "BEHAVIORAL" }, { "name": "Clinic directly observed therapy (DOT)", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 145, "start_date": "1995-09", "completion_date": "2015-12", "has_results": false, "last_update_posted_date": "2015-12-23", "last_synced_at": "2026-10-24T00:42:19.328Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00005739" }, { "nct_id": "NCT03976037", "title": "Buccal Versus Vaginal Misoprostol In Combination With Foley Bulb", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Induction of Labor" ], "interventions": [ { "name": "Misoprostol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Christiana Care Health Services", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "FEMALE", "summary": "18 Years to 55 Years · Female only" }, "enrollment_count": 216, "start_date": "2019-06-04", "completion_date": "2021-02-01", "has_results": false, "last_update_posted_date": "2021-02-26", "last_synced_at": "2026-10-24T00:42:19.328Z", "location_count": 1, "location_summary": "Newark, Delaware", "locations": [ { "city": "Newark", "state": "Delaware" } ], "official_url": "https://clinicaltrials.gov/study/NCT03976037" }, { "nct_id": "NCT06805994", "title": "Administering NMT to Reestablish Infant Nasal Microbiome Diversity Following Intranasal Mupirocin Treatment", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Staphylococcal Aureus Infection", "Microbial Colonization", "Pediatric Infection", "S. Aureus Colonization", "Microbial Transplant" ], "interventions": [ { "name": "Nasal Microbiota Transplant (NMT)", "type": "BIOLOGICAL" }, { "name": "Placebo", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Johns Hopkins University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "0 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "0 Years to 60 Years" }, "enrollment_count": 175, "start_date": "2025-08-27", "completion_date": "2028-01-01", "has_results": false, "last_update_posted_date": "2026-08-10", "last_synced_at": "2026-10-24T00:42:19.328Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT06805994" }, { "nct_id": "NCT01529151", "title": "Effectiveness of Osteopathic Manipulative Treatment (OMT) and Vestibular Rehabilitation Therapy (VRT) in Individuals With Vertigo", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Vertigo", "Dizziness", "Benign Paroxysmal Positional Vertigo", "Labyrinthitis" ], "interventions": [ { "name": "Osteopathic Manipulative Treatment (OMT)", "type": "OTHER" }, { "name": "Vestibular Rehabilitation Therapy (VRT)", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Western University of Health Sciences", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "79 Years", "sex": "ALL", "summary": "18 Years to 79 Years" }, "enrollment_count": 26, "start_date": "2012-01", "completion_date": "2014-08", "has_results": false, "last_update_posted_date": "2015-06-10", "last_synced_at": "2026-10-24T00:42:19.328Z", "location_count": 1, "location_summary": "Pomona, California", "locations": [ { "city": "Pomona", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01529151" }, { "nct_id": "NCT03305666", "title": "Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Drug Effect", "Rib Fractures", "Rib Trauma", "Surgical Procedure, Unspecified", "Pain; Catheter (Other)", "Nerve Pain", "Local Infiltration", "Anesthesia, Local", "Intercostal Rib", "Opioid Dependence", "Chest Injury Trauma", "Pneumonia" ], "interventions": [ { "name": "Liposomal bupivacaine injection", "type": "DRUG" }, { "name": "Bupivacaine indwelling catheter", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Denver Health and Hospital Authority", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 36, "start_date": "2017-10-05", "completion_date": "2021-01-31", "has_results": true, "last_update_posted_date": "2021-09-29", "last_synced_at": "2026-10-24T00:42:19.328Z", "location_count": 1, "location_summary": "Denver, Colorado", "locations": [ { "city": "Denver", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT03305666" }, { "nct_id": "NCT02590237", "title": "KingVision Video Laryngoscopy vs Direct Laryngoscopy - Equivalence Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Tracheal Intubation" ], "interventions": [ { "name": "Ambu KingVision Video Laryngoscope aBlade", "type": "DEVICE" }, { "name": "Miller Direct Laryngoscopy", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Ann & Robert H Lurie Children's Hospital of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": "2 Years", "sex": "ALL", "summary": "Up to 2 Years" }, "enrollment_count": 200, "start_date": "2015-10", "completion_date": "2016-09", "has_results": false, "last_update_posted_date": "2016-10-03", "last_synced_at": "2026-10-24T00:42:19.328Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02590237" }, { "nct_id": "NCT02272972", "title": "Performance Improvement Program on Imaging II", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Hip Fractures", "Femoral Fractures", "Fractures, Bone" ], "interventions": [ { "name": "Application of knowledge", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "AO Clinical Investigation and Publishing Documentation", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 250, "start_date": "2014-10", "completion_date": "2016-05", "has_results": false, "last_update_posted_date": "2020-08-13", "last_synced_at": "2026-10-24T00:42:19.328Z", "location_count": 1, "location_summary": "Columbia, Missouri", "locations": [ { "city": "Columbia", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT02272972" }, { "nct_id": "NCT06874595", "title": "Psychobiological Responses Following Exercise and Brain Stimulation", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Psychological" ], "interventions": [ { "name": "Cycling exercise at 65% of HRR for 20 minutes followed by HD-tDCS (exercise + HD-tDCS)", "type": "OTHER" }, { "name": "Cycling exercise at 65% of HRR exercise followed by sham HD-tDCS (exercise + sham tDCS)", "type": "OTHER" }, { "name": "No exercise followed by HD-tDCS (no exercise + HD-tDCS).", "type": "OTHER" }, { "name": "State Anxiety Inventory", "type": "OTHER" }, { "name": "Visual Analog Scale for Anxiety", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Virginia Commonwealth University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 29, "start_date": "2025-03-19", "completion_date": "2027-02", "has_results": false, "last_update_posted_date": "2026-03-16", "last_synced_at": "2026-10-24T00:42:19.328Z", "location_count": 1, "location_summary": "Richmond, Virginia", "locations": [ { "city": "Richmond", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT06874595" } ] }