{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Diabetes+Assistant+%28DiAs%29+with+Closed-Loop",
    "query": {
      "intervention": "Diabetes Assistant (DiAs) with Closed-Loop"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Diabetes+Assistant+%28DiAs%29+with+Closed-Loop&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-26T18:09:28.369Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02463682",
      "title": "Early Feasibility Study of Zone-MPC and HMS With DiAs in the Outpatient Setting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 1"
      ],
      "interventions": [
        {
          "name": "CGM and Insulin Pump",
          "type": "DEVICE"
        },
        {
          "name": "Closed-Loop Control System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sansum Diabetes Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 9,
      "start_date": "2015-05",
      "completion_date": "2015-10",
      "has_results": false,
      "last_update_posted_date": "2016-04-11",
      "last_synced_at": "2026-09-26T18:09:28.369Z",
      "location_count": 3,
      "location_summary": "Santa Barbara, California • Rochester, Minnesota • Charlottesville, Virginia",
      "locations": [
        {
          "city": "Santa Barbara",
          "state": "California"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02463682"
    },
    {
      "nct_id": "NCT02705053",
      "title": "At Home Study of a Zone-Model Predictive Control (MPC) Controller and a Health Monitoring System (HMS) With the Diabetes Assistant (DiAs) System and Run-to-Run Adaptation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Type 1 Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "CGM and Insulin Pump",
          "type": "DEVICE"
        },
        {
          "name": "Closed-Loop Control System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sansum Diabetes Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 32,
      "start_date": "2016-02",
      "completion_date": "2016-08",
      "has_results": false,
      "last_update_posted_date": "2016-10-14",
      "last_synced_at": "2026-09-26T18:09:28.369Z",
      "location_count": 3,
      "location_summary": "Santa Barbara, California • Rochester, Minnesota • Charlottesville, Virginia",
      "locations": [
        {
          "city": "Santa Barbara",
          "state": "California"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02705053"
    },
    {
      "nct_id": "NCT06041971",
      "title": "Fully Closed Loop At Home (FCL@Home)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 1 Diabetes"
      ],
      "interventions": [
        {
          "name": "AIDANET system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "14 Years to 60 Years"
      },
      "enrollment_count": 36,
      "start_date": "2023-11-01",
      "completion_date": "2025-05-05",
      "has_results": false,
      "last_update_posted_date": "2024-12-18",
      "last_synced_at": "2026-09-26T18:09:28.369Z",
      "location_count": 3,
      "location_summary": "San Francisco, California • Aurora, Colorado • Charlottesville, Virginia",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06041971"
    },
    {
      "nct_id": "NCT01939834",
      "title": "Early Feasibility Study of Adaptive Advisory/Automated (AAA) Control of Type 1 Diabetes",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 1 Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Overnight CLC",
          "type": "DEVICE"
        },
        {
          "name": "Sensor-Augmented Pump Therapy (SAP)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sue Brown",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "21 Years to 64 Years"
      },
      "enrollment_count": 10,
      "start_date": "2013-12",
      "completion_date": "2014-01",
      "has_results": true,
      "last_update_posted_date": "2026-06-15",
      "last_synced_at": "2026-09-26T18:09:28.369Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01939834"
    },
    {
      "nct_id": "NCT02137512",
      "title": "Pilot Study 3 of Outpatient Control-to-Range: Safety and Efficacy With Day-and-Night In-Home Use",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 1 Diabetes"
      ],
      "interventions": [
        {
          "name": "Closed-Loop Control System",
          "type": "DEVICE"
        },
        {
          "name": "Sensor-Augmented Pump (SAP)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Jaeb Center for Health Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "18 Years to 69 Years"
      },
      "enrollment_count": 30,
      "start_date": "2014-08",
      "completion_date": "2015-11",
      "has_results": true,
      "last_update_posted_date": "2018-10-29",
      "last_synced_at": "2026-09-26T18:09:28.369Z",
      "location_count": 3,
      "location_summary": "Santa Barbara, California • Stanford, California • Charlottesville, Virginia",
      "locations": [
        {
          "city": "Santa Barbara",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02137512"
    },
    {
      "nct_id": "NCT02750267",
      "title": "Closed-Loop Control in Young Children 5-8 Years Old Using DiAs Platform",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 1"
      ],
      "interventions": [
        {
          "name": "Diabetes Assistant (DiAs) with Closed-Loop",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "9 Years",
        "sex": "ALL",
        "summary": "5 Years to 9 Years"
      },
      "enrollment_count": 12,
      "start_date": "2016-05",
      "completion_date": "2016-05",
      "has_results": true,
      "last_update_posted_date": "2017-07-24",
      "last_synced_at": "2026-09-26T18:09:28.369Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02750267"
    },
    {
      "nct_id": "NCT01890954",
      "title": "Optimizing Closed-Loop Control of Type 1 Diabetes Mellitus in Adolescents",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 1"
      ],
      "interventions": [
        {
          "name": "Diabetes Assistant (DiAs)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "13 Years to 18 Years"
      },
      "enrollment_count": 17,
      "start_date": "2013-08",
      "completion_date": "2014-02",
      "has_results": true,
      "last_update_posted_date": "2022-09-13",
      "last_synced_at": "2026-09-26T18:09:28.369Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01890954"
    },
    {
      "nct_id": "NCT03234491",
      "title": "Improving Post-Prandial Blood Glucose Control With Afrezza During Closed-Loop Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Post-Prandial Hyperglycemia",
        "Post-Prandial Hypoglycemia"
      ],
      "interventions": [
        {
          "name": "DiAS",
          "type": "DEVICE"
        },
        {
          "name": "Afrezza low dose",
          "type": "DRUG"
        },
        {
          "name": "Afrezza high dose",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 15,
      "start_date": "2017-11-22",
      "completion_date": "2019-07-22",
      "has_results": false,
      "last_update_posted_date": "2022-05-25",
      "last_synced_at": "2026-09-26T18:09:28.369Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03234491"
    },
    {
      "nct_id": "NCT02147860",
      "title": "Full Day and Night Closed-Loop With DiAs Platform",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 1"
      ],
      "interventions": [
        {
          "name": "Diabetes Assistant (DiAs) with USS Virginia",
          "type": "DEVICE"
        },
        {
          "name": "Sensor Augmented Pump Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "10 Years to 35 Years"
      },
      "enrollment_count": 44,
      "start_date": "2014-05",
      "completion_date": "2015-01",
      "has_results": false,
      "last_update_posted_date": "2016-07-19",
      "last_synced_at": "2026-09-26T18:09:28.369Z",
      "location_count": 2,
      "location_summary": "Stanford, California • Charlottesville, Virginia",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02147860"
    },
    {
      "nct_id": "NCT01973413",
      "title": "Diabetes Assistant (DiAs) Control-to-Range (CTR) Nocturnal Closed-Loop Camp Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 1"
      ],
      "interventions": [
        {
          "name": "Diabetes Assistant (DiAs)",
          "type": "DEVICE"
        },
        {
          "name": "Tandem t:slim Insulin Pump",
          "type": "DEVICE"
        },
        {
          "name": "Dexcom G4 Platinum sensor",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "10 Years to 35 Years"
      },
      "enrollment_count": 32,
      "start_date": "2013-07",
      "completion_date": "2013-08",
      "has_results": true,
      "last_update_posted_date": "2015-04-24",
      "last_synced_at": "2026-09-26T18:09:28.369Z",
      "location_count": 1,
      "location_summary": "Los Gatos, California",
      "locations": [
        {
          "city": "Los Gatos",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01973413"
    }
  ]
}