{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Diaphragmatic+breathing+exercise",
    "query": {
      "intervention": "Diaphragmatic breathing exercise"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 47,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Diaphragmatic+breathing+exercise&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-16T01:26:24.083Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04776278",
      "title": "Behavioral Economic and Wellness-based Approaches for Reducing Alcohol Use and Consequences Among Emerging Adults",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alcohol Abuse"
      ],
      "interventions": [
        {
          "name": "Brief Alcohol Intervention (BAI)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Substance-free Activity Session (SFAS)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Relaxation Training (RT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Education Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Memphis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "29 Years",
        "sex": "ALL",
        "summary": "18 Years to 29 Years"
      },
      "enrollment_count": 525,
      "start_date": "2022-01-17",
      "completion_date": "2026-05-01",
      "has_results": false,
      "last_update_posted_date": "2025-09-10",
      "last_synced_at": "2026-09-16T01:26:24.083Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04776278"
    },
    {
      "nct_id": "NCT06205251",
      "title": "Diaphragm Structure and Function in Childhood Cancer Survivors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Childhood Cancer",
        "Cancer Survivors"
      ],
      "interventions": [
        {
          "name": "POWERbreathe Plus IMT",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "6 Years to 12 Years"
      },
      "enrollment_count": 7,
      "start_date": "2024-03-15",
      "completion_date": "2025-01-07",
      "has_results": false,
      "last_update_posted_date": "2026-03-30",
      "last_synced_at": "2026-09-16T01:26:24.083Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06205251"
    },
    {
      "nct_id": "NCT04660708",
      "title": "Manual Physical Therapy During Pregnancy on Post Partum Perineal Trauma and Pain",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pregnancy Related",
        "Delivery; Injury, Maternal",
        "Pelvic Floor Disorders"
      ],
      "interventions": [
        {
          "name": "manual physical therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Milwaukee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 105,
      "start_date": "2020-02-15",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2022-05-17",
      "last_synced_at": "2026-09-16T01:26:24.083Z",
      "location_count": 1,
      "location_summary": "Hales Corners, Wisconsin",
      "locations": [
        {
          "city": "Hales Corners",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04660708"
    },
    {
      "nct_id": "NCT03213522",
      "title": "Comparison of Craniosacral Therapy vs Pelvic Floor Physical Therapy",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Sclerosis",
        "Bladder Dysfunction",
        "Urinary Incontinence",
        "Overactive Bladder"
      ],
      "interventions": [
        {
          "name": "Pelvic Floor Physical Therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Craniosacral Therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "CentraState Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2017-04-10",
      "completion_date": "2018-04-09",
      "has_results": false,
      "last_update_posted_date": "2017-07-11",
      "last_synced_at": "2026-09-16T01:26:24.083Z",
      "location_count": 1,
      "location_summary": "Freehold, New Jersey",
      "locations": [
        {
          "city": "Freehold",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03213522"
    },
    {
      "nct_id": "NCT04897581",
      "title": "BBTI vs PSR in Musculoskeletal Orofacial Pain Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myofascial Pain",
        "Myalgia"
      ],
      "interventions": [
        {
          "name": "Brief Behavioral Therapy for Insomnia, BBTI",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Physical Self-Regulation, PSR",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Ian Boggero, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 19,
      "start_date": "2021-10-21",
      "completion_date": "2023-05-23",
      "has_results": false,
      "last_update_posted_date": "2026-06-17",
      "last_synced_at": "2026-09-16T01:26:24.083Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04897581"
    },
    {
      "nct_id": "NCT04679402",
      "title": "Diaphragm Function and Diver Endurance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Muscles"
      ],
      "interventions": [
        {
          "name": "Carbon monoxide 200 ppm in air",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 45,
      "start_date": "2022-04-14",
      "completion_date": "2024-04-30",
      "has_results": false,
      "last_update_posted_date": "2024-06-13",
      "last_synced_at": "2026-09-16T01:26:24.083Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04679402"
    },
    {
      "nct_id": "NCT03709199",
      "title": "Long Term Follow up of Children Enrolled in the REDvent Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Respiratory Distress Syndrome, Adult",
        "Ventilator-Induced Lung Injury",
        "Neurocognitive Dysfunction",
        "Quality of Life",
        "Respiration Disorders"
      ],
      "interventions": [
        {
          "name": "Ventilation Inhomogeneity",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Diaphragm Ultrasound",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Respiratory Inductance Plethysmography",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Spirometry",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Functional Residual Capacity",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "MIP/MEP",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "6 minute walk test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Neurocognitive Testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Emotional Health Assessment",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Health Related Quality of Life",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Functional Status",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Respiratory Status Questionnaire",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Children's Hospital Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "1 Month to 18 Years"
      },
      "enrollment_count": 176,
      "start_date": "2018-10-01",
      "completion_date": "2026-05-01",
      "has_results": false,
      "last_update_posted_date": "2025-04-17",
      "last_synced_at": "2026-09-16T01:26:24.083Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03709199"
    },
    {
      "nct_id": "NCT04960566",
      "title": "Targeting Hypervigilance and Autonomic Arousal: the Psycho-physiologic Model of Gastroesophageal Reflux Disease (GERD)",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gastroesophageal Reflux"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy",
          "type": "OTHER"
        },
        {
          "name": "Sham-SOC Lifestyle Coaching",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 250,
      "start_date": "2022-04-19",
      "completion_date": "2026-11-30",
      "has_results": false,
      "last_update_posted_date": "2025-08-11",
      "last_synced_at": "2026-09-16T01:26:24.083Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois • St Louis, Missouri",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04960566"
    },
    {
      "nct_id": "NCT05998018",
      "title": "Randomized Study of the pdSTIM™ System in Failure to Wean Mechanically Ventilated Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neuromodulation",
        "Phrenic Nerve Stimulation",
        "Ventilator Induced Diaphragm Dysfunction",
        "Mechanical Ventilation Weaning"
      ],
      "interventions": [
        {
          "name": "pdSTIM System Therapy",
          "type": "DEVICE"
        },
        {
          "name": "Conventional Medical Management",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Stimdia Medical Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2023-09-29",
      "completion_date": "2025-09-04",
      "has_results": false,
      "last_update_posted_date": "2026-03-27",
      "last_synced_at": "2026-09-16T01:26:24.083Z",
      "location_count": 21,
      "location_summary": "Mobile, Alabama • Chandler, Arizona • Goodyear, Arizona + 18 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Goodyear",
          "state": "Arizona"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05998018"
    },
    {
      "nct_id": "NCT01725854",
      "title": "Relaxation Response Training for PTSD Prevention in US Military Personnel",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Posttraumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Relaxation Response training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "William Beaumont Army Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2012-07",
      "completion_date": "2015-05",
      "has_results": false,
      "last_update_posted_date": "2016-11-02",
      "last_synced_at": "2026-09-16T01:26:24.083Z",
      "location_count": 1,
      "location_summary": "El Paso, Texas",
      "locations": [
        {
          "city": "El Paso",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01725854"
    }
  ]
}