{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Diphenhydramine+%28Benadryl%29&page=9", "query": { "intervention": "Diphenhydramine (Benadryl)", "page": 9 }, "page_size": 10 }, "pagination": { "page": 9, "page_size": 10, "total_count": 488, "total_pages": 49, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Diphenhydramine+%28Benadryl%29&page=10&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Diphenhydramine+%28Benadryl%29&page=8&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-13T20:27:42.714Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04743063", "title": "Prospective Monitoring of Angiotensin Receptor Neprilysin Inhibitor in Older Adults With Heart Failure and Frailty", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Heart Failure, Systolic", "Frailty" ], "interventions": [ { "name": "sacubitril/valsartan", "type": "DRUG" }, { "name": "Angiotensin II Receptor Blockers", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "65 Years", "maximum_age": null, "sex": "ALL", "summary": "65 Years and older" }, "enrollment_count": 40000, "start_date": "2021-01-14", "completion_date": "2022-12-31", "has_results": false, "last_update_posted_date": "2021-02-15", "last_synced_at": "2026-10-13T20:27:42.714Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04743063" }, { "nct_id": "NCT00185614", "title": "Non-myeloablative Allogeneic Transplantation for the Treatment of Multiple Myeloma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Blood Cancer", "Multiple Myeloma" ], "interventions": [ { "name": "Autologous hematopoietic cell transplant (Auto-HCT)", "type": "PROCEDURE" }, { "name": "Allogeneic hematopoietic cell transplant (Allo-HCT)", "type": "PROCEDURE" }, { "name": "Cyclophosphamide", "type": "DRUG" }, { "name": "Filgrastim", "type": "DRUG" }, { "name": "Melphalan", "type": "DRUG" }, { "name": "Total body irradiation (TBI)", "type": "RADIATION" }, { "name": "Cyclosporine (CSP)", "type": "PROCEDURE" }, { "name": "Mycophenolate Mofetil (MMF)", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DRUG", "RADIATION" ], "sponsor": "Wen-Kai Weng", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 63, "start_date": "2000-08", "completion_date": "2010-04", "has_results": true, "last_update_posted_date": "2018-01-18", "last_synced_at": "2026-10-13T20:27:42.714Z", "location_count": 1, "location_summary": "Stanford, California", "locations": [ { "city": "Stanford", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00185614" }, { "nct_id": "NCT00168779", "title": "Randomized, Double-Blind, Placebo-Controlled, Forced-Titration, Comparing Telmisartan vs Valsartan. Taken Orally for Eight Weeks in Patients With Stage 1 and Stage 2 Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "telmisartan 80 mg / hydrochlorothiazide 25 mg", "type": "DRUG" }, { "name": "valsartan 160 mg / hydrochlorothiazide 25 mg", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1185, "start_date": "2005-09", "completion_date": "2006-07", "has_results": false, "last_update_posted_date": "2017-12-28", "last_synced_at": "2026-10-13T20:27:42.714Z", "location_count": 113, "location_summary": "Athens, Alabama • Birmingham, Alabama • Huntsville, Alabama + 90 more", "locations": [ { "city": "Athens", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT00168779" }, { "nct_id": "NCT04815902", "title": "Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for Osteoarthritis", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Osteoarthritis, Knee" ], "interventions": [ { "name": "Fisetin", "type": "DRUG" }, { "name": "Losartan", "type": "DRUG" }, { "name": "Placebo - Losartan", "type": "DRUG" }, { "name": "Placebo Fisetin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Steadman Philippon Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "40 Years to 85 Years" }, "enrollment_count": 100, "start_date": "2021-05-18", "completion_date": "2025-06-01", "has_results": false, "last_update_posted_date": "2024-04-16", "last_synced_at": "2026-10-13T20:27:42.714Z", "location_count": 1, "location_summary": "Vail, Colorado", "locations": [ { "city": "Vail", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT04815902" }, { "nct_id": "NCT00274599", "title": "PROBE Investigation of the Safety & Efficacy of Telmisartan (Micardis®) vs Ramipril (Altace®) Using ABPM in HTN", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Telmisartan", "type": "DRUG" }, { "name": "Ramipril", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "19 Years", "maximum_age": null, "sex": "ALL", "summary": "19 Years and older" }, "enrollment_count": 812, "start_date": "2002-10-09", "completion_date": null, "has_results": false, "last_update_posted_date": "2023-12-06", "last_synced_at": "2026-10-13T20:27:42.714Z", "location_count": 43, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 40 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Long Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00274599" }, { "nct_id": "NCT02867800", "title": "Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Sickle Cell Disease", "Graft Versus Host Disease" ], "interventions": [ { "name": "Diphenhydramine", "type": "DRUG" }, { "name": "Acetaminophen", "type": "DRUG" }, { "name": "Methylprednisolone", "type": "DRUG" }, { "name": "Meperidine", "type": "DRUG" }, { "name": "Alemtuzumab", "type": "DRUG" }, { "name": "Thymoglobulin", "type": "DRUG" }, { "name": "Fludarabine", "type": "DRUG" }, { "name": "Melphalan", "type": "DRUG" }, { "name": "Thiotepa", "type": "DRUG" }, { "name": "Cyclosporine", "type": "DRUG" }, { "name": "Tacrolimus", "type": "DRUG" }, { "name": "Methotrexate", "type": "DRUG" }, { "name": "Abatacept", "type": "DRUG" }, { "name": "Marrow infusion", "type": "PROCEDURE" }, { "name": "Sirolimus", "type": "DRUG" }, { "name": "Mycophenolate Mofetil", "type": "DRUG" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Monica Bhatia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Years", "maximum_age": "20 Years", "sex": "ALL", "summary": "3 Years to 20 Years" }, "enrollment_count": 24, "start_date": "2016-07", "completion_date": "2023-12-30", "has_results": false, "last_update_posted_date": "2024-06-13", "last_synced_at": "2026-10-13T20:27:42.714Z", "location_count": 7, "location_summary": "Washington D.C., District of Columbia • Atlanta, Georgia • Chicago, Illinois + 4 more", "locations": [ { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02867800" }, { "nct_id": "NCT02278471", "title": "The SCCS Polypill Pilot Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hypertension", "Hyperlipidemia" ], "interventions": [ { "name": "Polypill (atorvastatin, amlodipine, losartan, and hydrochlorothiazide)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "45 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "45 Years to 75 Years" }, "enrollment_count": 303, "start_date": "2015-12", "completion_date": "2018-06-27", "has_results": true, "last_update_posted_date": "2021-05-14", "last_synced_at": "2026-10-13T20:27:42.714Z", "location_count": 1, "location_summary": "Mobile, Alabama", "locations": [ { "city": "Mobile", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT02278471" }, { "nct_id": "NCT01986361", "title": "Placebo-Controlled Onset-of-Action Study of Flurbiprofen Utilizing the Double-Stopwatch Method", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Acute Pharyngitis", "Sore Throat" ], "interventions": [ { "name": "flurbiprofen", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Reckitt Benckiser LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 122, "start_date": "2013-09", "completion_date": "2014-04", "has_results": true, "last_update_posted_date": "2017-09-28", "last_synced_at": "2026-10-13T20:27:42.714Z", "location_count": 1, "location_summary": "Storrs, Connecticut", "locations": [ { "city": "Storrs", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT01986361" }, { "nct_id": "NCT00051909", "title": "Efficacy and Safety of LY451395 in Patients With Probable Alzheimer's Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Alzheimer's Disease" ], "interventions": [ { "name": "LY451395", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 200, "start_date": "2002-11", "completion_date": "2003-06", "has_results": false, "last_update_posted_date": "2006-07-19", "last_synced_at": "2026-10-13T20:27:42.714Z", "location_count": 9, "location_summary": "Beverly Hills, California • Fresno, California • Boca Raton, Florida + 6 more", "locations": [ { "city": "Beverly Hills", "state": "California" }, { "city": "Fresno", "state": "California" }, { "city": "Boca Raton", "state": "Florida" }, { "city": "Fort Lauderdale", "state": "Florida" }, { "city": "Miami Beach", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00051909" }, { "nct_id": "NCT00675987", "title": "A Randomized Clinical Trial To Study Losartan On Endothelial Dysfunction and Insulin Resistance In Obese Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Obesity", "Hypertension", "Hyperglycemia" ], "interventions": [ { "name": "losartan", "type": "DRUG" }, { "name": "Placebo control", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 53, "start_date": "2007-05", "completion_date": "2008-12", "has_results": true, "last_update_posted_date": "2018-09-06", "last_synced_at": "2026-10-13T20:27:42.714Z", "location_count": 9, "location_summary": "Little Rock, Arkansas • San Diego, California • Miami, Florida + 6 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "San Diego", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00675987" } ] }