{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Direct+invasive+arterial+pressure", "query": { "intervention": "Direct invasive arterial pressure" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-22T19:10:13.007Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01502787", "title": "Comparison of Nebivolol and Metoprolol With Exercise and Angiotensin II in Hypertensive Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Metoprolol succinate", "type": "DRUG" }, { "name": "Nebivolol", "type": "DRUG" }, { "name": "Forearm blood flow", "type": "PROCEDURE" }, { "name": "Microneurography", "type": "PROCEDURE" }, { "name": "Rhythmic handgrip exercise", "type": "PROCEDURE" }, { "name": "Lower body negative pressure", "type": "PROCEDURE" }, { "name": "Angiotensin II", "type": "DRUG" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "University of Texas Southwestern Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 46, "start_date": "2009-04", "completion_date": "2013-06", "has_results": true, "last_update_posted_date": "2020-07-07", "last_synced_at": "2026-09-22T19:10:13.007Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01502787" }, { "nct_id": "NCT02102243", "title": "Neural Mechanism of Aldosterone-induced Insulin Resistance", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "DEFINITY® infusion", "type": "DRUG" }, { "name": "Human Recombinant Regular Insulin infusion", "type": "DRUG" }, { "name": "Dextrose infusion", "type": "DRUG" }, { "name": "Flow mediated vasodilation", "type": "PROCEDURE" }, { "name": "Endothelial cell collection", "type": "PROCEDURE" }, { "name": "Microvascular perfusion assessment using Definity", "type": "PROCEDURE" }, { "name": "Microneurography", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Wanpen Vongpatanasin", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 0, "start_date": "2010-11", "completion_date": "2025-12", "has_results": false, "last_update_posted_date": "2023-03-15", "last_synced_at": "2026-09-22T19:10:13.007Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02102243" }, { "nct_id": "NCT01996449", "title": "The Role of Aldosterone on Augmented Exercise Pressor Reflex in Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Eplerenone", "type": "DRUG" }, { "name": "Amlodipine", "type": "DRUG" }, { "name": "Microneurography", "type": "PROCEDURE" }, { "name": "Rhythmic handgrip exercise", "type": "PROCEDURE" }, { "name": "Sustained hand grip", "type": "PROCEDURE" }, { "name": "Forearm blood flow", "type": "PROCEDURE" }, { "name": "Arm cycling exercise", "type": "PROCEDURE" }, { "name": "Cold Pressor test", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "University of Texas Southwestern Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 14, "start_date": "2013-07", "completion_date": "2021-04", "has_results": true, "last_update_posted_date": "2022-03-18", "last_synced_at": "2026-09-22T19:10:13.007Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01996449" }, { "nct_id": "NCT00745602", "title": "The Effect of Atrial Fibrillation Hemodynamics on Regulation of Cerebral Blood Flow", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Atrial Fibrillation" ], "interventions": [ { "name": "non-invasive testing", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "University of Texas Southwestern Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2007-10", "completion_date": "2009-10", "has_results": false, "last_update_posted_date": "2019-01-09", "last_synced_at": "2026-09-22T19:10:13.007Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00745602" }, { "nct_id": "NCT05357066", "title": "Nitrous Oxide as Treatment for Fibromyalgia", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Fibromyalgia", "Central Neuropathic Pain" ], "interventions": [ { "name": "Nitrous oxide gas for inhalation", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 0, "start_date": "2021-11-12", "completion_date": "2026-02-27", "has_results": false, "last_update_posted_date": "2026-05-14", "last_synced_at": "2026-09-22T19:10:13.007Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT05357066" }, { "nct_id": "NCT06429332", "title": "International Care Bundle Evaluation in Cerebral Hemorrhage Research", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Intracerebral Hemorrhage", "Intracerebral Haemorrhage", "Intraventricular Hemorrhage", "Stroke", "Cerebrovascular Disease" ], "interventions": [ { "name": "Reversal of Oral anticoagulation within 30 minutes", "type": "OTHER" }, { "name": "Early intensive blood pressure lowering", "type": "OTHER" }, { "name": "Treatment of pyrexia", "type": "OTHER" }, { "name": "Hyperglycemia treatment", "type": "OTHER" }, { "name": "Do-not-resuscitate (DNR) or withdrawal of care", "type": "OTHER" }, { "name": "Referral to Intensive Care", "type": "OTHER" }, { "name": "Referral to Neurosurgery", "type": "OTHER" }, { "name": "Repeat brain imaging", "type": "DIAGNOSTIC_TEST" }, { "name": "Standard care", "type": "OTHER" } ], "intervention_types": [ "OTHER", "DIAGNOSTIC_TEST" ], "sponsor": "Region Skane", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 3500, "start_date": "2025-01-07", "completion_date": "2027-07", "has_results": false, "last_update_posted_date": "2026-05-22", "last_synced_at": "2026-09-22T19:10:13.007Z", "location_count": 1, "location_summary": "Oklahoma City, Oklahoma", "locations": [ { "city": "Oklahoma City", "state": "Oklahoma" } ], "official_url": "https://clinicaltrials.gov/study/NCT06429332" }, { "nct_id": "NCT03222414", "title": "Non-invasive Versus Invasive Blood Pressure Measurement in the Morbidly Obese Parturient With Severe Preeclampsia", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Pre-Eclampsia", "Morbid Obesity", "Parturient", "Blood Pressure" ], "interventions": [ { "name": "Non-invasive BP recording with conical Ultracheck Curve BP cuff", "type": "DEVICE" }, { "name": "Non-invasive BP recording with traditional cylindrical BP cuff", "type": "DEVICE" }, { "name": "Direct invasive arterial pressure", "type": "OTHER" } ], "intervention_types": [ "DEVICE", "OTHER" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 3, "start_date": "2015-05-01", "completion_date": "2016-01-18", "has_results": true, "last_update_posted_date": "2019-12-11", "last_synced_at": "2026-09-22T19:10:13.007Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT03222414" }, { "nct_id": "NCT05357040", "title": "Antidepressant Effects of Nitrous Oxide", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Major Depressive Disorder", "Treatment Resistant Depression" ], "interventions": [ { "name": "Nitrous oxide gas for inhalation", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2021-06-30", "completion_date": "2026-02-27", "has_results": false, "last_update_posted_date": "2026-05-14", "last_synced_at": "2026-09-22T19:10:13.007Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT05357040" }, { "nct_id": "NCT05710887", "title": "N2O for Acute Suicidality and Depression in the ED", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Suicidal Ideation", "Major Depressive Disorder", "Treatment Resistant Depression" ], "interventions": [ { "name": "Nitrous oxide gas for inhalation", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 0, "start_date": "2026-02-27", "completion_date": "2026-02-27", "has_results": false, "last_update_posted_date": "2026-03-04", "last_synced_at": "2026-09-22T19:10:13.007Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT05710887" }, { "nct_id": "NCT03407287", "title": "Peripheral Venous Analysis (PIVA) for Predicting Volume Responsiveness and Fluid Status", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Systemic Inflammatory Response Syndrome", "Distributive Shock", "Hypotension and Shock", "Decompensated Congestive Heart Failure", "Atrial Fibrillation", "High Risk Non-cardiac Surgery" ], "interventions": [ { "name": "Peripheral Intravenous Analysis (PIVA)", "type": "PROCEDURE" }, { "name": "Standard of care invasive vascular monitoring", "type": "PROCEDURE" }, { "name": "Standard noninvasive vascular monitoring", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 180, "start_date": "2018-01-08", "completion_date": "2020-12-01", "has_results": false, "last_update_posted_date": "2021-04-12", "last_synced_at": "2026-09-22T19:10:13.007Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT03407287" } ] }