{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Diuretic&page=2",
    "query": {
      "intervention": "Diuretic",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Diuretic&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-17T13:00:55.902Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04855097",
      "title": "Evaluation of Blood Volume Analysis- Guided Management of Decompensated Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Decompensated Heart Failure"
      ],
      "interventions": [
        {
          "name": "BVA-100",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Daxor Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 32,
      "start_date": "2022-05-01",
      "completion_date": "2022-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-09-29",
      "last_synced_at": "2026-09-17T13:00:55.902Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04855097"
    },
    {
      "nct_id": "NCT02031354",
      "title": "A Pilot Study of Dietary Chloride Supplementation on Cardiorenal Function in Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Lysine Chloride",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 11,
      "start_date": "2014-01",
      "completion_date": "2015-03",
      "has_results": false,
      "last_update_posted_date": "2018-06-27",
      "last_synced_at": "2026-09-17T13:00:55.902Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02031354"
    },
    {
      "nct_id": "NCT04112199",
      "title": "A Study for Evaluation of BIV201 to Reduce Ascites and Complications in Patients With Cirrhosis and Refractory Ascites",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Ascites",
        "Decompensated Cirrhosis"
      ],
      "interventions": [
        {
          "name": "BIV201 continuous infusion",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "BioVie Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 15,
      "start_date": "2021-06-17",
      "completion_date": "2023-05-08",
      "has_results": false,
      "last_update_posted_date": "2024-05-08",
      "last_synced_at": "2026-09-17T13:00:55.902Z",
      "location_count": 10,
      "location_summary": "Los Angeles, California • Jacksonville, Florida • Miami, Florida + 7 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04112199"
    },
    {
      "nct_id": "NCT04223271",
      "title": "Heart Failure Event Advance Detection Trial",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congestive Heart Failure",
        "Heart Failure",
        "Decompensated Heart Failure"
      ],
      "interventions": [
        {
          "name": "Indicor",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Vixiar Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 165,
      "start_date": "2020-02-04",
      "completion_date": "2021-04-30",
      "has_results": false,
      "last_update_posted_date": "2020-05-19",
      "last_synced_at": "2026-09-17T13:00:55.902Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04223271"
    },
    {
      "nct_id": "NCT05704595",
      "title": "Effectiveness of Outpatient Intravenous Diuretic Therapy for Treatment of Worsening Heart Failure (OUTPATIENT-WHF)",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Initial outpatient management strategy, including outpatient IV diuretics in clinic",
          "type": "OTHER"
        },
        {
          "name": "Initial hospitalization-based management strategy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2023-03-27",
      "completion_date": "2025-05",
      "has_results": false,
      "last_update_posted_date": "2025-04-27",
      "last_synced_at": "2026-09-17T13:00:55.902Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05704595"
    },
    {
      "nct_id": "NCT00605072",
      "title": "The Antihypertensives and Vascular, Endothelial and Cognitive Function Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cognitive Impairment",
        "Hypertension",
        "Aging"
      ],
      "interventions": [
        {
          "name": "candesartan",
          "type": "DRUG"
        },
        {
          "name": "lisinopril",
          "type": "DRUG"
        },
        {
          "name": "hydrochlorothiazide",
          "type": "DRUG"
        },
        {
          "name": "nifedipine, long acting",
          "type": "DRUG"
        },
        {
          "name": "metoprolol, long-acting",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 53,
      "start_date": "2008-01",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2013-02-15",
      "last_synced_at": "2026-09-17T13:00:55.902Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California • Boston, Massachusetts",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00605072"
    },
    {
      "nct_id": "NCT05534412",
      "title": "A Practice-Based Intervention To Improve Care for a Diverse Population Of Women With Urinary Incontinence",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Urinary Incontinence"
      ],
      "interventions": [
        {
          "name": "Academic Detailing",
          "type": "OTHER"
        },
        {
          "name": "Electronic Clinical Decision Support",
          "type": "OTHER"
        },
        {
          "name": "APP Co-management",
          "type": "OTHER"
        },
        {
          "name": "Electronic Referral",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1600,
      "start_date": "2022-09-07",
      "completion_date": "2027-02-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-13",
      "last_synced_at": "2026-09-17T13:00:55.902Z",
      "location_count": 4,
      "location_summary": "La Jolla, California • Los Angeles, California • Torrance, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05534412"
    },
    {
      "nct_id": "NCT00156572",
      "title": "Management of Hyponatremia in Preterm Infants on Diuretics",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Bronchopulmonary Dysplasia",
        "Hyponatremia on Diuretics"
      ],
      "interventions": [
        {
          "name": "Sodium supplementation",
          "type": "PROCEDURE"
        },
        {
          "name": "Fluid restriction",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Weeks",
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "4 Weeks to 6 Months"
      },
      "enrollment_count": 58,
      "start_date": "2005-04",
      "completion_date": "2007-12",
      "has_results": false,
      "last_update_posted_date": "2007-12-27",
      "last_synced_at": "2026-09-17T13:00:55.902Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00156572"
    },
    {
      "nct_id": "NCT04201704",
      "title": "Effect of Giving Reduced Fluid in Children After Trauma",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critical Illness",
        "Pediatrics",
        "General Surgery",
        "Fluid Therapy",
        "Wounds and Injuries"
      ],
      "interventions": [
        {
          "name": "Balanced crystalloid solution volume administration",
          "type": "OTHER"
        },
        {
          "name": "Packed Erythrocytes Units, Blood Product Unit volume",
          "type": "OTHER"
        },
        {
          "name": "Plasma volume",
          "type": "OTHER"
        },
        {
          "name": "Platelets volume",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "15 Years",
        "sex": "ALL",
        "summary": "6 Months to 15 Years"
      },
      "enrollment_count": 250,
      "start_date": "2018-08-27",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2026-05-07",
      "last_synced_at": "2026-09-17T13:00:55.902Z",
      "location_count": 4,
      "location_summary": "Buffalo, New York • New York, New York • Rochester, New York + 1 more",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Rochester",
          "state": "New York"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04201704"
    },
    {
      "nct_id": "NCT00886262",
      "title": "Study to Evaluate if the Drug Vasopressin Protects the Kidneys for Patients Undergoing Liver Transplant",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Liver Failure"
      ],
      "interventions": [
        {
          "name": "Vasopressin",
          "type": "DRUG"
        },
        {
          "name": "Normal saline placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 18,
      "start_date": "2007-07",
      "completion_date": "2011-08",
      "has_results": true,
      "last_update_posted_date": "2018-10-17",
      "last_synced_at": "2026-09-17T13:00:55.902Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00886262"
    }
  ]
}