{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Dose+de-escalation+to+gross+disease+to+contralateral+neck",
    "query": {
      "intervention": "Dose de-escalation to gross disease to contralateral neck"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 1,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-11-06T22:19:31.749Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07418034",
      "title": "A Single Arm Phase II Trial in p16-positive Oropharynx Cancer of Selective Dose De-escalation of nodAl VolumEs at Minimal Risk and Primary Site Disease (SAVED)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Head and Neck Cancer",
        "Head and Neck Squamous Cell Cancer",
        "Head and Neck Squamous Cell Carcinoma",
        "Oropharyngeal Carcinoma",
        "Oropharyngeal Squamous Cell Carcinoma (OPSCC)",
        "Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma",
        "Oropharyngeal Squamous Cell Carcinoma",
        "Oropharyngeal Squamous Cell Carcinoma (SCC)",
        "Oropharyngeal Squamous Cell Carcinoma (OPSCCA)",
        "Oropharyngeal Cancer",
        "Oropharyngeal Squamous Cell Cancer",
        "HPV Positive Oropharyngeal Squamous Cell Carcinoma",
        "HPV (Human Papillomavirus)-Associated Carcinoma",
        "HPV 16 Positive Oropharyngeal Tumors (OPC)"
      ],
      "interventions": [
        {
          "name": "Dose de-escalation to contralateral neck.",
          "type": "RADIATION"
        },
        {
          "name": "Dose de-escalation to gross disease to contralateral neck",
          "type": "RADIATION"
        },
        {
          "name": "Dose de-escalation to gross disease",
          "type": "RADIATION"
        },
        {
          "name": "Circulating Tumor DNA test (ctDNA test)",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "RADIATION",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 132,
      "start_date": "2026-10-19",
      "completion_date": "2033-05",
      "has_results": false,
      "last_update_posted_date": "2026-11-06",
      "last_synced_at": "2026-11-06T22:19:31.749Z",
      "location_count": 4,
      "location_summary": "Baltimore, Maryland • Columbia, Maryland • Glen Burnie, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Columbia",
          "state": "Maryland"
        },
        {
          "city": "Glen Burnie",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07418034"
    }
  ]
}