{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Doxycycline+hyclate+%28Doryx%29&page=4", "query": { "intervention": "Doxycycline hyclate (Doryx)", "page": 4 }, "page_size": 10 }, "pagination": { "page": 4, "page_size": 10, "total_count": 174, "total_pages": 18, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Doxycycline+hyclate+%28Doryx%29&page=5&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Doxycycline+hyclate+%28Doryx%29&page=3&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-13T14:53:20.763Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05853120", "title": "Doxy-Post-exposure Prophylaxis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Sexually Transmitted Diseases" ], "interventions": [ { "name": "Doxycycline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "59 Years", "sex": "ALL", "summary": "18 Years to 59 Years" }, "enrollment_count": 45, "start_date": "2023-05-31", "completion_date": "2024-12-24", "has_results": true, "last_update_posted_date": "2025-09-11", "last_synced_at": "2026-10-13T14:53:20.763Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT05853120" }, { "nct_id": "NCT00322465", "title": "NGU: Doxycycline (Plus or Minus Tinidazole) Versus Azithromycin (Plus or Minus Tinidazole)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Urethritis" ], "interventions": [ { "name": "Doxycycline", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" }, { "name": "Tinidazole", "type": "DRUG" }, { "name": "Azithromycin", "type": "DRUG" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": "45 Years", "sex": "MALE", "summary": "16 Years to 45 Years · Male only" }, "enrollment_count": 305, "start_date": "2006-11-17", "completion_date": "2009-04-20", "has_results": true, "last_update_posted_date": "2026-08-27", "last_synced_at": "2026-10-13T14:53:20.763Z", "location_count": 4, "location_summary": "Birmingham, Alabama • New Orleans, Louisiana • Baltimore, Maryland + 1 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "New Orleans", "state": "Louisiana" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Chapel Hill", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00322465" }, { "nct_id": "NCT00016835", "title": "Treating Periodontal Infection: Effects on Glycemic", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Periodontal Disease", "Diabetes Mellitus, Type 2" ], "interventions": [ { "name": "Supra-gingival scaling and placebo", "type": "PROCEDURE" }, { "name": "Subgingival scaling and metronidazole", "type": "PROCEDURE" }, { "name": "Subgingival scaling and doxycycline", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "University of Michigan", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 46, "start_date": "2001-10-17", "completion_date": "2004-09-03", "has_results": false, "last_update_posted_date": "2017-07-19", "last_synced_at": "2026-10-13T14:53:20.763Z", "location_count": 1, "location_summary": "Ann Arbor, Michigan", "locations": [ { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT00016835" }, { "nct_id": "NCT01867294", "title": "Spironolactone in Preventing Rash in Patients With Advanced Cancer Receiving Panitumumab and Cetuximab", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Advanced Malignant Neoplasm", "Dermatologic Complication" ], "interventions": [ { "name": "Doxycycline", "type": "DRUG" }, { "name": "Management of Therapy Complications", "type": "PROCEDURE" }, { "name": "Placebo", "type": "OTHER" }, { "name": "Questionnaire Administration", "type": "OTHER" }, { "name": "Spironolactone", "type": "DRUG" }, { "name": "Sunscreen", "type": "DRUG" }, { "name": "Therapeutic Hydrocortisone", "type": "DRUG" } ], "intervention_types": [ "DRUG", "PROCEDURE", "OTHER" ], "sponsor": "Academic and Community Cancer Research United", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 19, "start_date": "2012-08-31", "completion_date": "2014-06-13", "has_results": true, "last_update_posted_date": "2020-01-09", "last_synced_at": "2026-10-13T14:53:20.763Z", "location_count": 5, "location_summary": "Urbana, Illinois • Des Moines, Iowa • Wichita, Kansas + 2 more", "locations": [ { "city": "Urbana", "state": "Illinois" }, { "city": "Des Moines", "state": "Iowa" }, { "city": "Wichita", "state": "Kansas" }, { "city": "Saint Cloud", "state": "Minnesota" }, { "city": "Marshfield", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT01867294" }, { "nct_id": "NCT04233424", "title": "D-PLEX 311: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Surgical Site Infection", "Colon Surgery", "Abdominal Surgery", "Post-Op Infection" ], "interventions": [ { "name": "D-PLEX", "type": "DRUG" }, { "name": "Standard of Care (SoC)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "PolyPid Ltd.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 977, "start_date": "2020-06-24", "completion_date": "2022-09-02", "has_results": true, "last_update_posted_date": "2026-04-21", "last_synced_at": "2026-10-13T14:53:20.763Z", "location_count": 5, "location_summary": "Sheffield, Alabama • Los Angeles, California • Redding, California + 2 more", "locations": [ { "city": "Sheffield", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "Redding", "state": "California" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Bend", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT04233424" }, { "nct_id": "NCT02099240", "title": "Patients Response to Early Switch To Oral:Osteomyelitis Study", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Osteomyelitis" ], "interventions": [ { "name": "oral antibiotics", "type": "DRUG" }, { "name": "intravenous antibiotics", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Julio Ramirez", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 11, "start_date": "2014-03-06", "completion_date": "2018-11-07", "has_results": false, "last_update_posted_date": "2021-04-06", "last_synced_at": "2026-10-13T14:53:20.763Z", "location_count": 1, "location_summary": "Louisville, Kentucky", "locations": [ { "city": "Louisville", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT02099240" }, { "nct_id": "NCT06120140", "title": "Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Carcinoma, Non-Small-Cell Lung" ], "interventions": [ { "name": "Amivantamab IV", "type": "DRUG" }, { "name": "Amivantamab SC", "type": "DRUG" }, { "name": "Lazertinib", "type": "DRUG" }, { "name": "Doxycycline", "type": "DRUG" }, { "name": "Minocycline", "type": "DRUG" }, { "name": "Clindamycin", "type": "DRUG" }, { "name": "Chlorhexidine", "type": "DRUG" }, { "name": "Noncomedogenic skin moisturizer", "type": "OTHER" }, { "name": "Ruxolitinib", "type": "OTHER" }, { "name": "Tacrolimus", "type": "OTHER" }, { "name": "Zinc gluconate", "type": "DRUG" }, { "name": "Propranolol", "type": "DRUG" }, { "name": "Timolol", "type": "DRUG" }, { "name": "Clobetasol", "type": "DRUG" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 305, "start_date": "2024-02-16", "completion_date": "2030-06-30", "has_results": false, "last_update_posted_date": "2026-09-25", "last_synced_at": "2026-10-13T14:53:20.763Z", "location_count": 28, "location_summary": "Chandler, Arizona • Duarte, California • Fullerton, California + 25 more", "locations": [ { "city": "Chandler", "state": "Arizona" }, { "city": "Duarte", "state": "California" }, { "city": "Fullerton", "state": "California" }, { "city": "Glendale", "state": "California" }, { "city": "Huntington Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06120140" }, { "nct_id": "NCT07498010", "title": "Doxycycline Use in Post-Operative Seromas", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Seroma" ], "interventions": [ { "name": "Doxycycline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Miami", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10, "start_date": "2026-05-31", "completion_date": "2027-10-01", "has_results": false, "last_update_posted_date": "2026-07-09", "last_synced_at": "2026-10-13T14:53:20.763Z", "location_count": 1, "location_summary": "Coral Gables, Florida", "locations": [ { "city": "Coral Gables", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07498010" }, { "nct_id": "NCT00775177", "title": "Bioequivalence Study of Doxycycline Monohydrate 100mg Tablets Under Fasting Conditions", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Doxycycline monohydrate 100mg tablets", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ranbaxy Laboratories Limited", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 32, "start_date": "2005-06", "completion_date": "2005-08", "has_results": false, "last_update_posted_date": "2008-10-20", "last_synced_at": "2026-10-13T14:53:20.763Z", "location_count": 1, "location_summary": "Chapel Hill, North Carolina", "locations": [ { "city": "Chapel Hill", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00775177" }, { "nct_id": "NCT00648180", "title": "Food Study of Doxycycline Monohydrate Tablets 100 mg and Adoxa Tablets 100 mg", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Doxycycline Monohydrate Tablets 100 mg", "type": "DRUG" }, { "name": "Adoxa Tablets 100 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mylan Pharmaceuticals Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 36, "start_date": "2005-07", "completion_date": "2005-08", "has_results": false, "last_update_posted_date": "2024-04-24", "last_synced_at": "2026-10-13T14:53:20.763Z", "location_count": 1, "location_summary": "Morgantown, West Virginia", "locations": [ { "city": "Morgantown", "state": "West Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00648180" } ] }