{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Doxycycline+monohydrate+200+mg",
    "query": {
      "intervention": "Doxycycline monohydrate 200 mg"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 19,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Doxycycline+monohydrate+200+mg&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-29T11:45:31.618Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06738407",
      "title": "Doxycycline Prophylaxis for Prevention of Sexually Transmitted Infections",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Gonorrhea",
        "Chlamydia",
        "Syphilis",
        "Sexually Transmitted Infections (STIs)"
      ],
      "interventions": [
        {
          "name": "Doxycycline hyclate delayed released 200 mg",
          "type": "DRUG"
        },
        {
          "name": "Doxycycline hyclate delayed released 200 mg weekly",
          "type": "DRUG"
        },
        {
          "name": "Per standard of care with quarterly STI testing/treatment and sexual health counseling",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Westat",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "29 Years",
        "sex": "FEMALE",
        "summary": "13 Years to 29 Years · Female only"
      },
      "enrollment_count": 760,
      "start_date": "2026-02-27",
      "completion_date": "2028-06-15",
      "has_results": false,
      "last_update_posted_date": "2026-05-15",
      "last_synced_at": "2026-09-29T11:45:31.618Z",
      "location_count": 13,
      "location_summary": "Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 10 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06738407"
    },
    {
      "nct_id": "NCT04370782",
      "title": "Hydroxychloroquine and Zinc With Either Azithromycin or Doxycycline for Treatment of COVID-19 in Outpatient Setting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "COVID-19"
      ],
      "interventions": [
        {
          "name": "Hydroxychloroquine",
          "type": "DRUG"
        },
        {
          "name": "Azithromycin",
          "type": "DRUG"
        },
        {
          "name": "Zinc Sulfate",
          "type": "DRUG"
        },
        {
          "name": "Doxycycline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Francis Hospital, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "30 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2020-04-28",
      "completion_date": "2020-09-30",
      "has_results": false,
      "last_update_posted_date": "2020-12-09",
      "last_synced_at": "2026-09-29T11:45:31.618Z",
      "location_count": 1,
      "location_summary": "Roslyn, New York",
      "locations": [
        {
          "city": "Roslyn",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04370782"
    },
    {
      "nct_id": "NCT07755618",
      "title": "Characterization of Doxycycline Pharmacokinetics and Adherence",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Sexually Transmitted Infection"
      ],
      "interventions": [
        {
          "name": "Single-Dose PK Phase - DR Group",
          "type": "DRUG"
        },
        {
          "name": "Single-Dose PK Phase - IR Group",
          "type": "DRUG"
        },
        {
          "name": "Multi-Dose PK Phase - Daily Group",
          "type": "DRUG"
        },
        {
          "name": "Multi-Dose PK Phase - Intermittent Group",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "HIV Prevention Trials Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 16,
      "start_date": "2026-08-27",
      "completion_date": "2027-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-09-17",
      "last_synced_at": "2026-09-29T11:45:31.618Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07755618"
    },
    {
      "nct_id": "NCT02086591",
      "title": "A Phase II Study of Doxycycline in Relapsed NHL",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Adult Diffuse Large B-Cell Lymphoma",
        "Mantle Cell Lymphoma Recurrent",
        "Lymphoma, Follicular",
        "Marginal Zone B-Cell Lymphoma",
        "Malignant Lymphoma - Lymphoplasmacytic",
        "Waldenstrom Macroglobulinemia",
        "Small Lymphocytic Lymphoma",
        "Chronic Lymphocytic Leukemia (CLL)",
        "T-Cell Lymphoma"
      ],
      "interventions": [
        {
          "name": "Doxycycline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 7,
      "start_date": "2014-03",
      "completion_date": "2015-11",
      "has_results": true,
      "last_update_posted_date": "2016-12-22",
      "last_synced_at": "2026-09-29T11:45:31.618Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02086591"
    },
    {
      "nct_id": "NCT05296837",
      "title": "Ocular Rosacea Biome Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Ocular Rosacea",
        "Antimicrobial Resistance"
      ],
      "interventions": [
        {
          "name": "Doxycycline 40 MG ( 20mg twice daily)",
          "type": "DRUG"
        },
        {
          "name": "Doxycycline 200 MG ( 100 mg twice daily)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 46,
      "start_date": "2023-06-22",
      "completion_date": "2025-07-14",
      "has_results": false,
      "last_update_posted_date": "2026-08-20",
      "last_synced_at": "2026-09-29T11:45:31.618Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05296837"
    },
    {
      "nct_id": "NCT02899000",
      "title": "A Treatment for Severe Inflammatory Acne Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Acne Vulgaris"
      ],
      "interventions": [
        {
          "name": "Adapalene 0.3% / benzoyl peroxide 2.5% emulsion gel",
          "type": "DRUG"
        },
        {
          "name": "Oral doxycycline hyclate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Galderma R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 186,
      "start_date": "2016-07-29",
      "completion_date": "2017-06-27",
      "has_results": true,
      "last_update_posted_date": "2022-12-09",
      "last_synced_at": "2026-09-29T11:45:31.618Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02899000"
    },
    {
      "nct_id": "NCT00322465",
      "title": "NGU: Doxycycline (Plus or Minus Tinidazole) Versus Azithromycin (Plus or Minus Tinidazole)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Urethritis"
      ],
      "interventions": [
        {
          "name": "Doxycycline",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        },
        {
          "name": "Tinidazole",
          "type": "DRUG"
        },
        {
          "name": "Azithromycin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "45 Years",
        "sex": "MALE",
        "summary": "16 Years to 45 Years · Male only"
      },
      "enrollment_count": 305,
      "start_date": "2006-11-17",
      "completion_date": "2009-04-20",
      "has_results": true,
      "last_update_posted_date": "2026-08-27",
      "last_synced_at": "2026-09-29T11:45:31.618Z",
      "location_count": 4,
      "location_summary": "Birmingham, Alabama • New Orleans, Louisiana • Baltimore, Maryland + 1 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00322465"
    },
    {
      "nct_id": "NCT03980223",
      "title": "Evaluation of Doxycycline Post-exposure Prophylaxis to Reduce Sexually Transmitted Infections in PrEP Users and HIV-infected Men Who Have Sex With Men",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Gonorrhea",
        "Chlamydia",
        "Syphilis"
      ],
      "interventions": [
        {
          "name": "Doxycycline Hyclate Delayed-Release 200 mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 641,
      "start_date": "2019-11-26",
      "completion_date": "2023-06-12",
      "has_results": true,
      "last_update_posted_date": "2024-07-12",
      "last_synced_at": "2026-09-29T11:45:31.618Z",
      "location_count": 3,
      "location_summary": "San Francisco, California • Seattle, Washington",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03980223"
    },
    {
      "nct_id": "NCT07215325",
      "title": "Got Doxy- 'Flipping the Script' on STI PEP",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Sexually Transmitted Infections (STI)"
      ],
      "interventions": [
        {
          "name": "Doxycycline monohydrate 200 mg",
          "type": "DRUG"
        },
        {
          "name": "Observation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 200,
      "start_date": "2025-10-13",
      "completion_date": "2029-04-13",
      "has_results": false,
      "last_update_posted_date": "2026-04-30",
      "last_synced_at": "2026-09-29T11:45:31.618Z",
      "location_count": 2,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07215325"
    },
    {
      "nct_id": "NCT05072093",
      "title": "Parrying the Pitfalls of PrEP: Project PEACH",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "HIV",
        "STI"
      ],
      "interventions": [
        {
          "name": "PrEP discontinuation intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Offering of on-demand oral PrEP",
          "type": "DRUG"
        },
        {
          "name": "Offering of STI PEP",
          "type": "DRUG"
        },
        {
          "name": "Injectable PrEP",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "MALE",
        "summary": "18 Years to 45 Years · Male only"
      },
      "enrollment_count": 240,
      "start_date": "2021-11-20",
      "completion_date": "2025-03-31",
      "has_results": true,
      "last_update_posted_date": "2026-04-01",
      "last_synced_at": "2026-09-29T11:45:31.618Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05072093"
    }
  ]
}