{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=E-cigarette+e-liquid&page=2",
    "query": {
      "intervention": "E-cigarette e-liquid",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=E-cigarette+e-liquid&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-29T16:10:49.524Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05327439",
      "title": "Using ANDS to Reduce Harm for Low SES Cigarette Smokers",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking, Cigarette",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Nicotine (electronic cigarette)",
          "type": "OTHER"
        },
        {
          "name": "Nicotine (nicotine pouch)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2022-03-23",
      "completion_date": "2023-02-09",
      "has_results": false,
      "last_update_posted_date": "2023-01-26",
      "last_synced_at": "2026-09-29T16:10:49.524Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05327439"
    },
    {
      "nct_id": "NCT05962229",
      "title": "Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Nicotine Dependence",
        "Nicotine Vaping"
      ],
      "interventions": [
        {
          "name": "(S)-Nicotine",
          "type": "DRUG"
        },
        {
          "name": "(R)- nicotine",
          "type": "DRUG"
        },
        {
          "name": "Racemic nicotine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 18,
      "start_date": "2024-12-06",
      "completion_date": "2027-05",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-09-29T16:10:49.524Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05962229"
    },
    {
      "nct_id": "NCT04238832",
      "title": "Salt-Based E-cigarette",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "Salt Base Nicotine",
          "type": "OTHER"
        },
        {
          "name": "Free Base Nicotine",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2020-06-16",
      "completion_date": "2021-07-23",
      "has_results": false,
      "last_update_posted_date": "2021-08-09",
      "last_synced_at": "2026-09-29T16:10:49.524Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04238832"
    },
    {
      "nct_id": "NCT03843047",
      "title": "Electronic Cigarette Unit Price Manipulations in the Experimental Tobacco Marketplace",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "3 mg/mL nicotine strength e-liquid",
          "type": "DRUG"
        },
        {
          "name": "6 mg/mL nicotine strength e-liquid",
          "type": "DRUG"
        },
        {
          "name": "12 mg/mL nicotine strength e-liquid",
          "type": "DRUG"
        },
        {
          "name": "24 mg/mL nicotine strength e-liquid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Virginia Polytechnic Institute and State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 81,
      "start_date": "2019-03-01",
      "completion_date": "2021-09-30",
      "has_results": false,
      "last_update_posted_date": "2022-11-22",
      "last_synced_at": "2026-09-29T16:10:49.524Z",
      "location_count": 1,
      "location_summary": "Roanoke, Virginia",
      "locations": [
        {
          "city": "Roanoke",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03843047"
    },
    {
      "nct_id": "NCT03243630",
      "title": "Effects of Flavors on Nicotine Reinforcement in Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "IV nicotine",
          "type": "DRUG"
        },
        {
          "name": "Menthol flavor",
          "type": "DRUG"
        },
        {
          "name": "green apple",
          "type": "DRUG"
        },
        {
          "name": "green apple and menthol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 26,
      "start_date": "2018-04-23",
      "completion_date": "2019-01-31",
      "has_results": true,
      "last_update_posted_date": "2020-12-03",
      "last_synced_at": "2026-09-29T16:10:49.524Z",
      "location_count": 1,
      "location_summary": "West Haven, Connecticut",
      "locations": [
        {
          "city": "West Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03243630"
    },
    {
      "nct_id": "NCT02600273",
      "title": "Novel Approaches to Reducing Tobacco Related Harm",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Tobacco Smoking Behavior",
        "Cigarette Smoking"
      ],
      "interventions": [
        {
          "name": "Usual brand cigarettes",
          "type": "OTHER"
        },
        {
          "name": "Lower nicotine content cigarettes",
          "type": "OTHER"
        },
        {
          "name": "Electronic cigarettes 1",
          "type": "OTHER"
        },
        {
          "name": "Electronic cigarettes 2",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2017-01",
      "completion_date": "2019-06",
      "has_results": false,
      "last_update_posted_date": "2020-09-30",
      "last_synced_at": "2026-09-29T16:10:49.524Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02600273"
    },
    {
      "nct_id": "NCT04053868",
      "title": "Evaluating the Comparative Pharmacokinetics of Nicotine After Administration Via JUUL or Tobacco Cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Administration & Dosage",
        "E-cigarettes",
        "Vaping",
        "E-Liquid",
        "Tobacco Smoking"
      ],
      "interventions": [
        {
          "name": "JUUL",
          "type": "OTHER"
        },
        {
          "name": "Tobacco",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 17,
      "start_date": "2019-12-09",
      "completion_date": "2022-03-31",
      "has_results": true,
      "last_update_posted_date": "2025-10-16",
      "last_synced_at": "2026-09-29T16:10:49.524Z",
      "location_count": 2,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04053868"
    },
    {
      "nct_id": "NCT05932745",
      "title": "Effects of Novel E-cigarette Constituents on Adults TCORS 3.0",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Use Disorder"
      ],
      "interventions": [
        {
          "name": "E-liquid coolant (No WS-3) for non-menthol (1)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (No WS-3) for low (0.1%) menthol (1)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (No WS-3) for high (2.0%) menthol (1)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (Low [0.1%] WS-3) for non-menthol (2)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (Low [0.1%] WS-3) for low (0.1%) menthol (2)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (Low [0.1%] WS-3) for high (2.0%) menthol (2)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (High [2.0%] WS-3) for non-menthol (3)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (High [2.0%] WS-3) for low (0.1%) menthol (3)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (High [2.0%] WS-3) for high (2.0%) menthol (3)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (Low [0.1%] WS-23) for non-menthol (4)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (Low [0.1%] WS-23) for low (0.1%) menthol (4)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (Low [0.1%] WS-23) for high (2.0%) menthol (4)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (High [2.0%] WS-23) for non-menthol (5)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (High [2.0%] WS-23) for low (0.1%) menthol (5)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (High [2.0%] WS-23) for high (2.0%) menthol (5)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (4% WS-23) for non-menthol (6)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (4% WS-23) for low (0.1%) menthol (6)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (4% WS-23) for high (2.0%) menthol (6)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 66,
      "start_date": "2025-06-20",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2026-06-16",
      "last_synced_at": "2026-09-29T16:10:49.524Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05932745"
    },
    {
      "nct_id": "NCT03635333",
      "title": "Effects of E-Cigarette Flavors on Adults TCORS 2.0",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Nicotine Use Disorder"
      ],
      "interventions": [
        {
          "name": "Nicotine",
          "type": "DRUG"
        },
        {
          "name": "Flavor",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "21 Years to 50 Years"
      },
      "enrollment_count": 130,
      "start_date": "2019-05-14",
      "completion_date": "2023-07-12",
      "has_results": true,
      "last_update_posted_date": "2025-12-19",
      "last_synced_at": "2026-09-29T16:10:49.524Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03635333"
    },
    {
      "nct_id": "NCT05960305",
      "title": "CSD201204 An Actual Use Study of P12 Electronic Nicotine Delivery System Among U.S. Adult Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking, Tobacco"
      ],
      "interventions": [
        {
          "name": "P1213416",
          "type": "OTHER"
        },
        {
          "name": "P1213422",
          "type": "OTHER"
        },
        {
          "name": "P1213716",
          "type": "OTHER"
        },
        {
          "name": "P1213722",
          "type": "OTHER"
        },
        {
          "name": "P1211216",
          "type": "OTHER"
        },
        {
          "name": "P1211222",
          "type": "OTHER"
        },
        {
          "name": "P1213616",
          "type": "OTHER"
        },
        {
          "name": "P1213622",
          "type": "OTHER"
        },
        {
          "name": "P1213816",
          "type": "OTHER"
        },
        {
          "name": "P1213822",
          "type": "OTHER"
        },
        {
          "name": "P1211916",
          "type": "OTHER"
        },
        {
          "name": "P1211922",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "RAI Services Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 1845,
      "start_date": "2023-09-15",
      "completion_date": "2024-01-28",
      "has_results": false,
      "last_update_posted_date": "2024-02-23",
      "last_synced_at": "2026-09-29T16:10:49.524Z",
      "location_count": 12,
      "location_summary": "Phoenix, Arizona • Fort Lauderdale, Florida • Orlando, Florida + 9 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05960305"
    }
  ]
}