{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=E-cigarette+e-liquid&page=4",
    "query": {
      "intervention": "E-cigarette e-liquid",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 73,
    "total_pages": 8,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=E-cigarette+e-liquid&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=E-cigarette+e-liquid&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-15T11:20:00.749Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03379740",
      "title": "Study to Investigate the Nicotine Pharmacokinetic Profiles and Pharmacodynamic Effects of P4M3 Variants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vaping",
        "Nicotine Absorption"
      ],
      "interventions": [
        {
          "name": "E-cigarette",
          "type": "OTHER"
        },
        {
          "name": "P4M3-1.7%",
          "type": "OTHER"
        },
        {
          "name": "P4M3-1.7%LA",
          "type": "OTHER"
        },
        {
          "name": "P4M3-3%LA",
          "type": "OTHER"
        },
        {
          "name": "P4M3-4%LA",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Philip Morris Products S.A.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 15,
      "start_date": "2017-07-11",
      "completion_date": "2017-12-01",
      "has_results": true,
      "last_update_posted_date": "2019-11-22",
      "last_synced_at": "2026-11-15T11:20:00.749Z",
      "location_count": 1,
      "location_summary": "High Point, North Carolina",
      "locations": [
        {
          "city": "High Point",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03379740"
    },
    {
      "nct_id": "NCT04449510",
      "title": "Short-Term Cardiovascular Effects of E-Cigarettes: Influence of E-Liquid pH",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Risk Factor",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Electronic Cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 14,
      "start_date": "2021-01-04",
      "completion_date": "2024-07-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-15",
      "last_synced_at": "2026-11-15T11:20:00.749Z",
      "location_count": 2,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04449510"
    },
    {
      "nct_id": "NCT05932693",
      "title": "Effect of Different E-cigarette Cooling Flavors on Adults' Sensory Experience TCORS 3.0",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "E-Cig Use"
      ],
      "interventions": [
        {
          "name": "E-liquid coolant (WS-3, 0.05%)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (WS-3, 0.1%)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (WS-3, 0.5%)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (WS-3, 1.0%)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (WS-3, 2.0%)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (menthol, 0.05%)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (menthol, 0.1%)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (menthol, 0.5%)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (menthol, 1.0%)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (menthol, 2.0%)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (WS-23, 0.05%)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (WS-23, 0.1%)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (WS-23, 0.5%)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (WS-23, 1.0%)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (WS-23, 2.0%)",
          "type": "OTHER"
        },
        {
          "name": "E-liquid coolant (WS-23, 4.0%)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 31,
      "start_date": "2024-09-03",
      "completion_date": "2025-01-09",
      "has_results": true,
      "last_update_posted_date": "2026-02-18",
      "last_synced_at": "2026-11-15T11:20:00.749Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05932693"
    },
    {
      "nct_id": "NCT03826303",
      "title": "The Impact of Vaping Ethanol in the Evaluation of Impairment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use"
      ],
      "interventions": [
        {
          "name": "E-cigarette liquid with ethanol, 1 puff",
          "type": "OTHER"
        },
        {
          "name": "E-cigarette liquid without ethanol, 1 puff",
          "type": "OTHER"
        },
        {
          "name": "E-cigarette liquid with ethanol, 10 puffs",
          "type": "OTHER"
        },
        {
          "name": "E-cigarette liquid without ethanol, 10 puffs",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 17,
      "start_date": "2021-04-02",
      "completion_date": "2022-04-08",
      "has_results": false,
      "last_update_posted_date": "2022-04-19",
      "last_synced_at": "2026-11-15T11:20:00.749Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03826303"
    },
    {
      "nct_id": "NCT05327439",
      "title": "Using ANDS to Reduce Harm for Low SES Cigarette Smokers",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking, Cigarette",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Nicotine (electronic cigarette)",
          "type": "OTHER"
        },
        {
          "name": "Nicotine (nicotine pouch)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2022-03-23",
      "completion_date": "2023-02-09",
      "has_results": false,
      "last_update_posted_date": "2023-01-26",
      "last_synced_at": "2026-11-15T11:20:00.749Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05327439"
    },
    {
      "nct_id": "NCT06260683",
      "title": "A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-cigarettes on Smoking Behavior",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoking-Related Carcinoma"
      ],
      "interventions": [
        {
          "name": "Nicotine Replacement",
          "type": "DRUG"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        },
        {
          "name": "Vaping",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Ohio State University Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 1500,
      "start_date": "2024-04-10",
      "completion_date": "2028-04-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-06",
      "last_synced_at": "2026-11-15T11:20:00.749Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06260683"
    },
    {
      "nct_id": "NCT02918630",
      "title": "E-cigarettes to Promote Smoking Reduction Among Individuals With Schizophrenia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Smoking"
      ],
      "interventions": [
        {
          "name": "Nicotine Patch",
          "type": "DRUG"
        },
        {
          "name": "E-cigarette",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 7,
      "start_date": "2016-10",
      "completion_date": "2017-08",
      "has_results": true,
      "last_update_posted_date": "2018-07-05",
      "last_synced_at": "2026-11-15T11:20:00.749Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02918630"
    },
    {
      "nct_id": "NCT04058717",
      "title": "Low Nicotine Cigarettes Plus Electronic Cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Dependence"
      ],
      "interventions": [
        {
          "name": "Normal Nicotine Content research cigarettes",
          "type": "OTHER"
        },
        {
          "name": "High Nicotine e-cigarette",
          "type": "OTHER"
        },
        {
          "name": "Very Low Nicotine Content research cigarettes",
          "type": "OTHER"
        },
        {
          "name": "Zero Nicotine e-cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 88,
      "start_date": "2021-06-01",
      "completion_date": "2024-08-12",
      "has_results": true,
      "last_update_posted_date": "2025-09-11",
      "last_synced_at": "2026-11-15T11:20:00.749Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04058717"
    },
    {
      "nct_id": "NCT04047836",
      "title": "Vaping High vs. Low Nicotine E-Liquid",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Risk Factor",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Low Nicotine E-Liquid",
          "type": "OTHER"
        },
        {
          "name": "Medium or High Nicotine E-Liquid",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 0,
      "start_date": "2023-06-01",
      "completion_date": "2023-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-08-22",
      "last_synced_at": "2026-11-15T11:20:00.749Z",
      "location_count": 2,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04047836"
    },
    {
      "nct_id": "NCT06208202",
      "title": "Perceptions of E-Cigarettes and Synthetic Cooling Agents, The ICE Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Abuse Tobacco",
        "Exposure"
      ],
      "interventions": [
        {
          "name": "Behavioral Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Biospecimen Collection",
          "type": "OTHER"
        },
        {
          "name": "Survey Administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Ohio State University Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "29 Years",
        "sex": "ALL",
        "summary": "21 Years to 29 Years"
      },
      "enrollment_count": 158,
      "start_date": "2024-05-08",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2026-06-15",
      "last_synced_at": "2026-11-15T11:20:00.749Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06208202"
    }
  ]
}