{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=E-cigarette+with+5%25+Nicotine+with+Tobacco+Flavor+Only",
    "query": {
      "intervention": "E-cigarette with 5% Nicotine with Tobacco Flavor Only"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-10T04:33:13.043Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02575885",
      "title": "Nicotine Delivery From Novel Non-Tobacco Electronic System in Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoker",
        "Current Smoker",
        "Healthy Subject"
      ],
      "interventions": [
        {
          "name": "Electronic Cigarette",
          "type": "OTHER"
        },
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        },
        {
          "name": "Pharmacological Study",
          "type": "OTHER"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Roswell Park Cancer Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 36,
      "start_date": "2016-03-16",
      "completion_date": "2018-06-06",
      "has_results": false,
      "last_update_posted_date": "2018-06-12",
      "last_synced_at": "2026-10-10T04:33:13.043Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02575885"
    },
    {
      "nct_id": "NCT03473483",
      "title": "Cigarette Harm Reduction With Electronic Cigarette Use",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence",
        "Tobacco Toxicity",
        "Nicotine Dependence, Cigarettes",
        "Cardiovascular Risk Factor",
        "Nicotine Withdrawal"
      ],
      "interventions": [
        {
          "name": "SREC",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 0,
      "start_date": "2022-08-01",
      "completion_date": "2026-03-31",
      "has_results": false,
      "last_update_posted_date": "2022-12-09",
      "last_synced_at": "2026-10-10T04:33:13.043Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03473483"
    },
    {
      "nct_id": "NCT04640285",
      "title": "Nicotine Uptake, Measures of Abuse Liability, and Puffing Topography With Use of RELX ENDS Products by Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use"
      ],
      "interventions": [
        {
          "name": "RELX ENDS Tobacco Flavor",
          "type": "OTHER"
        },
        {
          "name": "RELX ENDS Menthol Flavor",
          "type": "OTHER"
        },
        {
          "name": "Usual Brand Cigarette",
          "type": "OTHER"
        },
        {
          "name": "Nicorette White Ice Mint nicotine polacrilex gum",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Cheerain HK Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "59 Years",
        "sex": "ALL",
        "summary": "22 Years to 59 Years"
      },
      "enrollment_count": 41,
      "start_date": "2020-11-03",
      "completion_date": "2021-03-19",
      "has_results": false,
      "last_update_posted_date": "2021-03-24",
      "last_synced_at": "2026-10-10T04:33:13.043Z",
      "location_count": 1,
      "location_summary": "Overland Park, Kansas",
      "locations": [
        {
          "city": "Overland Park",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04640285"
    },
    {
      "nct_id": "NCT04019626",
      "title": "A Study to Assess Tobacco-related Biomarkers of Exposure in Smokers Using myBlu E-cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Continue-smoking",
          "type": "OTHER"
        },
        {
          "name": "myblu Tobacco 2.5%",
          "type": "OTHER"
        },
        {
          "name": "myblu Tobacco 4.0%",
          "type": "OTHER"
        },
        {
          "name": "myblu Honeymoon 2.5%",
          "type": "OTHER"
        },
        {
          "name": "myblu Honeymoon 4.0%",
          "type": "OTHER"
        },
        {
          "name": "JUUL 5%",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Fontem Ventures BV",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 240,
      "start_date": "2019-03-01",
      "completion_date": "2020-12-31",
      "has_results": true,
      "last_update_posted_date": "2021-06-30",
      "last_synced_at": "2026-10-10T04:33:13.043Z",
      "location_count": 1,
      "location_summary": "Lincoln, Nebraska",
      "locations": [
        {
          "city": "Lincoln",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04019626"
    },
    {
      "nct_id": "NCT05023096",
      "title": "Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Nicotine Delivery System Flavors"
      ],
      "interventions": [
        {
          "name": "Tobacco product administration and assessment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 71,
      "start_date": "2022-04-14",
      "completion_date": "2024-10-15",
      "has_results": true,
      "last_update_posted_date": "2026-04-22",
      "last_synced_at": "2026-10-10T04:33:13.043Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05023096"
    },
    {
      "nct_id": "NCT05278065",
      "title": "E-cigarettes for Harm Reduction in Adults With Asthma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Asthma",
        "Electronic Cigarette Use",
        "Cigarette Smoking"
      ],
      "interventions": [
        {
          "name": "Nicotine",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 17,
      "start_date": "2022-05-01",
      "completion_date": "2024-09-12",
      "has_results": true,
      "last_update_posted_date": "2025-11-18",
      "last_synced_at": "2026-10-10T04:33:13.043Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05278065"
    },
    {
      "nct_id": "NCT06077240",
      "title": "Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Smoking Behaviors",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "E-cigarette with 2.4% Nicotine with Menthol and Tobacco Flavors",
          "type": "BEHAVIORAL"
        },
        {
          "name": "E-cigarette with 2.4% Nicotine with Tobacco Flavor Only",
          "type": "BEHAVIORAL"
        },
        {
          "name": "E-cigarette with 5% Nicotine with Menthol and Tobacco Flavors",
          "type": "BEHAVIORAL"
        },
        {
          "name": "E-cigarette with 5% Nicotine with Tobacco Flavor Only",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tobacco Pouches with 3mg Nicotine with Menthol and Tobacco Flavors",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tobacco Pouches with 3mg Nicotine with Tobacco Flavor Only",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tobacco Pouches with 6mg Nicotine with Menthol and Tobacco Flavors",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tobacco Pouches with 6mg Nicotine with Tobacco Flavor Only",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 256,
      "start_date": "2024-08-20",
      "completion_date": "2028-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-19",
      "last_synced_at": "2026-10-10T04:33:13.043Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06077240"
    },
    {
      "nct_id": "NCT05327439",
      "title": "Using ANDS to Reduce Harm for Low SES Cigarette Smokers",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking, Cigarette",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Nicotine (electronic cigarette)",
          "type": "OTHER"
        },
        {
          "name": "Nicotine (nicotine pouch)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2022-03-23",
      "completion_date": "2023-02-09",
      "has_results": false,
      "last_update_posted_date": "2023-01-26",
      "last_synced_at": "2026-10-10T04:33:13.043Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05327439"
    },
    {
      "nct_id": "NCT05383508",
      "title": "Nicotine Pharmacokinetics Following Use of the P4M3 Gen 2.0 E-Cigarette Compared to Smoking Cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Vaping",
        "Nicotine",
        "Vaping"
      ],
      "interventions": [
        {
          "name": "CA35",
          "type": "OTHER"
        },
        {
          "name": "CM35",
          "type": "OTHER"
        },
        {
          "name": "Cig",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Philip Morris Products S.A.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "24 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "24 Years to 65 Years"
      },
      "enrollment_count": 36,
      "start_date": "2022-04-28",
      "completion_date": "2022-08-25",
      "has_results": true,
      "last_update_posted_date": "2024-04-26",
      "last_synced_at": "2026-10-10T04:33:13.043Z",
      "location_count": 1,
      "location_summary": "High Point, North Carolina",
      "locations": [
        {
          "city": "High Point",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05383508"
    }
  ]
}