{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=ECIG",
    "query": {
      "intervention": "ECIG"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 22,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=ECIG&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-08T23:48:52.001Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06856525",
      "title": "Dissolved Phase HXe-129 MRI: A Novel Biomarker to Quantify Pulmonary Pathology",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Electronic Cigarette Related Lung Damage"
      ],
      "interventions": [
        {
          "name": "Hyperpolarized xenon 129",
          "type": "DRUG"
        },
        {
          "name": "Cardiopulmonary Stress Test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Pulmonary Function Test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Chest CT",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Y. Michael Shim, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 80,
      "start_date": "2024-12-19",
      "completion_date": "2032-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-17",
      "last_synced_at": "2026-09-08T23:48:52.001Z",
      "location_count": 2,
      "location_summary": "Durham, North Carolina • Charlottesville, Virginia",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06856525"
    },
    {
      "nct_id": "NCT05971823",
      "title": "Effects of Electronic Cigarette Flavors on Abuse Liability in Smokers (P3-Taste)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use"
      ],
      "interventions": [
        {
          "name": "Tobacco product administration and assessment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 32,
      "start_date": "2023-07-31",
      "completion_date": "2024-07-26",
      "has_results": true,
      "last_update_posted_date": "2026-04-06",
      "last_synced_at": "2026-09-08T23:48:52.001Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05971823"
    },
    {
      "nct_id": "NCT05869318",
      "title": "Respiratory Effects of E-Cigarettes in Obese Youth",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "E-Cig Use"
      ],
      "interventions": [
        {
          "name": "ECIG own",
          "type": "OTHER"
        },
        {
          "name": "ECIG Vuse",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Ohio State University Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "21 Years to 25 Years"
      },
      "enrollment_count": 56,
      "start_date": "2023-04-04",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-20",
      "last_synced_at": "2026-09-08T23:48:52.001Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05869318"
    },
    {
      "nct_id": "NCT04378907",
      "title": "Assessing Electronic Cigarette Nicotine Flux",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use"
      ],
      "interventions": [
        {
          "name": "Cigarette Smoker/ECIG users: 0 mg/ml nicotine concentration",
          "type": "OTHER"
        },
        {
          "name": "Cigarette Smokers/ECIG users: 6 mg/ml nicotine concentration",
          "type": "OTHER"
        },
        {
          "name": "Cigarette Smokers/ECIG users: 15 mg/ml nicotine concentration",
          "type": "OTHER"
        },
        {
          "name": "Cigarette Smokers/ECIG users: 30 mg/ml nicotine concentration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 33,
      "start_date": "2021-01-05",
      "completion_date": "2023-02-01",
      "has_results": true,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-09-08T23:48:52.001Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04378907"
    },
    {
      "nct_id": "NCT07786896",
      "title": "Evaluation of Dependence and Nicotine Replacement Therapy-Supported Cessation Efforts Among Regular Electronic Cigarette Use",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "E Cigarette Use",
        "Cessation, Tobacco",
        "Cessation, Nicotine"
      ],
      "interventions": [
        {
          "name": "Nicotine Replacement Therapies",
          "type": "DRUG"
        },
        {
          "name": "Brief Behavioral Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "West Virginia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2026-09-01",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-26",
      "last_synced_at": "2026-09-08T23:48:52.001Z",
      "location_count": 2,
      "location_summary": "Greenville, North Carolina • Morgantown, West Virginia",
      "locations": [
        {
          "city": "Greenville",
          "state": "North Carolina"
        },
        {
          "city": "Morgantown",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07786896"
    },
    {
      "nct_id": "NCT04332926",
      "title": "Effects of E-Cigarette Nicotine Content in Smokers (Nicotine Flux Study)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use"
      ],
      "interventions": [
        {
          "name": "Tobacco product administration and assessment, own brand cigarettes",
          "type": "OTHER"
        },
        {
          "name": "Tobacco product administration and assessment, ECIG 30 Watts, 0 mg/ml nicotine",
          "type": "OTHER"
        },
        {
          "name": "Tobacco product administration and assessment, ECIG 30 Watts, 8 mg/ml nicotine",
          "type": "OTHER"
        },
        {
          "name": "Tobacco product administration and assessment, ECIG 30 Watts, 15 mg/ml nicotine",
          "type": "OTHER"
        },
        {
          "name": "Tobacco product administration and assessment, ECIG 30 Watts, 30 mg/ml nicotine",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 44,
      "start_date": "2021-01-05",
      "completion_date": "2023-09-08",
      "has_results": true,
      "last_update_posted_date": "2025-02-13",
      "last_synced_at": "2026-09-08T23:48:52.001Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04332926"
    },
    {
      "nct_id": "NCT02553577",
      "title": "Impact of Electronic Cigarettes on Perinatal Immune Responsiveness and Birth Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Immune Response",
        "Birth Weight",
        "Gestational Age"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Kristin Ashford",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "44 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 44 Years · Female only"
      },
      "enrollment_count": 278,
      "start_date": "2016-01-13",
      "completion_date": "2021-02-28",
      "has_results": false,
      "last_update_posted_date": "2021-07-07",
      "last_synced_at": "2026-09-08T23:48:52.001Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02553577"
    },
    {
      "nct_id": "NCT03861078",
      "title": "The Effect of Electronic Cigarette Liquid Characteristics in Smokers.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarettes"
      ],
      "interventions": [
        {
          "name": "Own Brand Cigarette",
          "type": "OTHER"
        },
        {
          "name": "ECIG 15 mg nicotine, sweetened",
          "type": "OTHER"
        },
        {
          "name": "ECIG 15 mg nicotine, unsweet",
          "type": "OTHER"
        },
        {
          "name": "ECIG 0 mg nicotine, sweetened",
          "type": "OTHER"
        },
        {
          "name": "ECIG 0 mg nicotine, unsweet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "21 Years to 55 Years"
      },
      "enrollment_count": 22,
      "start_date": "2020-02-17",
      "completion_date": "2021-12-13",
      "has_results": true,
      "last_update_posted_date": "2022-12-23",
      "last_synced_at": "2026-09-08T23:48:52.001Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03861078"
    },
    {
      "nct_id": "NCT05458895",
      "title": "Evaluating E-Cigarette Nicotine Form, Concentration, and Flavors Among Youth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "E-cigarette Use"
      ],
      "interventions": [
        {
          "name": "ECIG lab session 1",
          "type": "OTHER"
        },
        {
          "name": "ECIG lab session 2",
          "type": "OTHER"
        },
        {
          "name": "ECIG lab session 3",
          "type": "OTHER"
        },
        {
          "name": "ECIG lab session 4",
          "type": "OTHER"
        },
        {
          "name": "ECIG lab session 5",
          "type": "OTHER"
        },
        {
          "name": "ECIG lab session 6",
          "type": "OTHER"
        },
        {
          "name": "ECIG lab session 7",
          "type": "OTHER"
        },
        {
          "name": "ECIG lab session 8",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Ohio State University Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "21 Years to 25 Years"
      },
      "enrollment_count": 88,
      "start_date": "2021-12-02",
      "completion_date": "2023-08-07",
      "has_results": true,
      "last_update_posted_date": "2024-11-22",
      "last_synced_at": "2026-09-08T23:48:52.001Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05458895"
    },
    {
      "nct_id": "NCT02964182",
      "title": "Very Low Nicotine Content Cigarettes and E-Cigarettes in Promoting Smoking Cessation in Daily and Intermittent Cigarette Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoking-Related Carcinoma",
        "Tobacco-Related Carcinoma"
      ],
      "interventions": [
        {
          "name": "Cigarette",
          "type": "DRUG"
        },
        {
          "name": "Nicotine Replacement",
          "type": "DRUG"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        },
        {
          "name": "Survey Administration",
          "type": "OTHER"
        },
        {
          "name": "Very Low Nicotine Content Cigarette",
          "type": "DRUG"
        },
        {
          "name": "ECIG-Hi",
          "type": "DEVICE"
        },
        {
          "name": "ECIG-Lo",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 213,
      "start_date": "2017-10-26",
      "completion_date": "2025-03-04",
      "has_results": true,
      "last_update_posted_date": "2025-12-09",
      "last_synced_at": "2026-09-08T23:48:52.001Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02964182"
    }
  ]
}