{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=EVP-6124", "query": { "intervention": "EVP-6124" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 12, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=EVP-6124&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-06T08:11:40.427Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01714713", "title": "A 26-Week Extension Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Schizophrenia", "Impaired Cognition" ], "interventions": [ { "name": "EVP-6124", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "FORUM Pharmaceuticals Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 830, "start_date": "2013-06", "completion_date": "2015-10", "has_results": false, "last_update_posted_date": "2016-05-03", "last_synced_at": "2026-09-06T08:11:40.427Z", "location_count": 69, "location_summary": "Little Rock, Arkansas • Anaheim, California • Bellflower, California + 66 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Anaheim", "state": "California" }, { "city": "Bellflower", "state": "California" }, { "city": "Cerritos", "state": "California" }, { "city": "Chino", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01714713" }, { "nct_id": "NCT00968851", "title": "Safety and Cognitive Function Study of EVP-6124 in Patients With Schizophrenia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Schizophrenia", "Central Nervous System Diseases", "Cognition" ], "interventions": [ { "name": "EVP-6124", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "FORUM Pharmaceuticals Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 317, "start_date": "2009-12", "completion_date": "2011-03", "has_results": false, "last_update_posted_date": "2014-04-25", "last_synced_at": "2026-09-06T08:11:40.427Z", "location_count": 14, "location_summary": "Glendale, California • Oceanside, California • San Diego, California + 10 more", "locations": [ { "city": "Glendale", "state": "California" }, { "city": "Oceanside", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Sherman Oaks", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00968851" }, { "nct_id": "NCT01556763", "title": "Safety, Tolerability, and Pharmacokinetic Study of EVP-6124 in Patients With Schizophrenia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Schizophrenia", "Schizoaffective Disorder", "Central Nervous System Diseases" ], "interventions": [ { "name": "EVP-6124 (0.3 mg/day)", "type": "DRUG" }, { "name": "EVP-6124 (1.0 mg/day)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Antipsychotic therapy", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "FORUM Pharmaceuticals Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 21, "start_date": "2008-04", "completion_date": "2008-08", "has_results": true, "last_update_posted_date": "2012-06-21", "last_synced_at": "2026-09-06T08:11:40.427Z", "location_count": 1, "location_summary": "Wichita, Kansas", "locations": [ { "city": "Wichita", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01556763" }, { "nct_id": "NCT01969123", "title": "Study of the Safety and Effectiveness of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Alzheimer's Disease", "Dementia" ], "interventions": [ { "name": "Drug: EVP-6124", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "FORUM Pharmaceuticals Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "55 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "55 Years to 85 Years" }, "enrollment_count": 474, "start_date": "2013-10", "completion_date": "2017-01", "has_results": false, "last_update_posted_date": "2016-05-03", "last_synced_at": "2026-09-06T08:11:40.427Z", "location_count": 44, "location_summary": "Phoenix, Arizona • Tucson, Arizona • Costa Mesa, California + 41 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Costa Mesa", "state": "California" }, { "city": "Encino", "state": "California" }, { "city": "Glendale", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01969123" }, { "nct_id": "NCT01480232", "title": "A Safety and Cognitive Function Study of EVP-6124 Versus Placebo in Subjects With Nicotine Dependence", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Nicotine Dependence", "Smoking Cessation" ], "interventions": [ { "name": "EVP-6124", "type": "DRUG" }, { "name": "Placebo Capsule", "type": "DRUG" }, { "name": "NicoDerm Patch (Active)", "type": "DRUG" }, { "name": "NRT Patch (Placebo)", "type": "DRUG" }, { "name": "Brief Supportive and Behavioral Treatment", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "A. Eden Evins", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 345, "start_date": "2011-12", "completion_date": "2015-09", "has_results": true, "last_update_posted_date": "2017-04-06", "last_synced_at": "2026-09-06T08:11:40.427Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01480232" }, { "nct_id": "NCT01073228", "title": "Safety and Cognitive Function Study of EVP-6124 in Patients With Mild to Moderate Alzheimer's Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Alzheimer's Disease", "Central Nervous System Diseases", "Cognition" ], "interventions": [ { "name": "EVP-6124", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "FORUM Pharmaceuticals Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "50 Years to 85 Years" }, "enrollment_count": 409, "start_date": "2010-04", "completion_date": "2012-02", "has_results": false, "last_update_posted_date": "2014-04-25", "last_synced_at": "2026-09-06T08:11:40.427Z", "location_count": 25, "location_summary": "Phoenix, Arizona • Chino, California • Costa Mesa, California + 21 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Chino", "state": "California" }, { "city": "Costa Mesa", "state": "California" }, { "city": "Orange", "state": "California" }, { "city": "Santa Rosa", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01073228" }, { "nct_id": "NCT01716975", "title": "Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Schizophrenia", "Impaired Cognition" ], "interventions": [ { "name": "EVP-6124", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "FORUM Pharmaceuticals Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 767, "start_date": "2012-10", "completion_date": "2016-02", "has_results": false, "last_update_posted_date": "2016-05-03", "last_synced_at": "2026-09-06T08:11:40.427Z", "location_count": 49, "location_summary": "Phoenixville, Arizona • Little Rock, Arkansas • Cerritos, California + 46 more", "locations": [ { "city": "Phoenixville", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Cerritos", "state": "California" }, { "city": "Chino", "state": "California" }, { "city": "Costa Mesa", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01716975" }, { "nct_id": "NCT01714661", "title": "Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Schizophrenia", "Impaired Cognition" ], "interventions": [ { "name": "EVP-6124", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "FORUM Pharmaceuticals Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 753, "start_date": "2012-10", "completion_date": "2015-12", "has_results": false, "last_update_posted_date": "2016-05-03", "last_synced_at": "2026-09-06T08:11:40.427Z", "location_count": 38, "location_summary": "Tucson, Arizona • Anaheim, California • Bellflower, California + 35 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Bellflower", "state": "California" }, { "city": "Costa Mesa", "state": "California" }, { "city": "Culver City", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01714661" }, { "nct_id": "NCT01969136", "title": "Study of the Safety and Effectiveness of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Alzheimer's Disease", "Dementia" ], "interventions": [ { "name": "Drug: EVP-6124", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "FORUM Pharmaceuticals Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "55 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "55 Years to 85 Years" }, "enrollment_count": 403, "start_date": "2013-10", "completion_date": "2017-01", "has_results": false, "last_update_posted_date": "2016-05-03", "last_synced_at": "2026-09-06T08:11:40.427Z", "location_count": 42, "location_summary": "Tucson, Arizona • Little Rock, Arkansas • Culver City, California + 39 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Culver City", "state": "California" }, { "city": "Downey", "state": "California" }, { "city": "Los Alamitos", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01969136" }, { "nct_id": "NCT02004392", "title": "Study of the Safety and Clinical Effects of 2 Doses of EVP-6124 in Subjects With Alzheimer's Disease Who Complete Study EVP-6124-024 or EVP-6124-025", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Alzheimer's Disease", "Dementia" ], "interventions": [ { "name": "EVP-6124", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "FORUM Pharmaceuticals Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "55 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "55 Years to 85 Years" }, "enrollment_count": 348, "start_date": "2014-06", "completion_date": "2017-08", "has_results": false, "last_update_posted_date": "2016-05-03", "last_synced_at": "2026-09-06T08:11:40.427Z", "location_count": 56, "location_summary": "Phoenix, Arizona • Tucson, Arizona • Little Rock, Arkansas + 53 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Costa Mesa", "state": "California" }, { "city": "Culver City", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02004392" } ] }