{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Early+Start+Denver+Model+%28ESDM%29",
    "query": {
      "intervention": "Early Start Denver Model (ESDM)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-02T06:13:04.574Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03307057",
      "title": "Promoting Transactional Supports to Optimize Social Communication Outcomes for Infants and Their Families",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autism Spectrum Disorder"
      ],
      "interventions": [
        {
          "name": "Social Communication Growth Charts (SCGC)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Parent-Implemented (P-I) Condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Clinician-Implemented (C-I) Condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "6 Months to 6 Months"
      },
      "enrollment_count": 269,
      "start_date": "2018-02-01",
      "completion_date": "2024-10-08",
      "has_results": false,
      "last_update_posted_date": "2025-12-19",
      "last_synced_at": "2026-09-02T06:13:04.574Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03307057"
    },
    {
      "nct_id": "NCT07522190",
      "title": "Trial of Center-Based Early Start Denver Model vs. Pivotal Response Treatment in Children With Autism",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autism Spectrum Disorder (ASD)",
        "Autism"
      ],
      "interventions": [
        {
          "name": "Early Start Denver Model (ESDM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pivotal Response Treatment (PRT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Developmental Reciprocity Treatment (DRT)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "4 Years",
        "sex": "ALL",
        "summary": "2 Years to 4 Years"
      },
      "enrollment_count": 140,
      "start_date": "2027-01",
      "completion_date": "2037-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-08",
      "last_synced_at": "2026-09-02T06:13:04.574Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07522190"
    },
    {
      "nct_id": "NCT02272192",
      "title": "Intervention Effects of Intensity and Delivery Style for Toddlers With Autism",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autism Spectrum Disorder"
      ],
      "interventions": [
        {
          "name": "Early Start Denver Model (ESDM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Early Intensive Behavioral Intervention (EIBI)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Months",
        "maximum_age": "30 Months",
        "sex": "ALL",
        "summary": "15 Months to 30 Months"
      },
      "enrollment_count": 87,
      "start_date": "2013-03",
      "completion_date": "2019-07-01",
      "has_results": false,
      "last_update_posted_date": "2020-01-06",
      "last_synced_at": "2026-09-02T06:13:04.574Z",
      "location_count": 3,
      "location_summary": "Sacramento, California • Nashville, Tennessee • Seattle, Washington",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02272192"
    },
    {
      "nct_id": "NCT03889821",
      "title": "Mindfulness Training and Parent-coaching Interventions for Autism Spectrum Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autism Spectrum Disorder",
        "Parents",
        "Stress"
      ],
      "interventions": [
        {
          "name": "Parent-implemented Early Start Denver Model",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mindfulness Based Stress Reduction",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Months and older"
      },
      "enrollment_count": 63,
      "start_date": "2015-03-11",
      "completion_date": "2018-03-23",
      "has_results": false,
      "last_update_posted_date": "2019-03-26",
      "last_synced_at": "2026-09-02T06:13:04.574Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03889821"
    },
    {
      "nct_id": "NCT00698997",
      "title": "Intensive Intervention for Toddlers With Autism (EARLY STEPS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autism",
        "Autism Spectrum Disorder"
      ],
      "interventions": [
        {
          "name": "Early Start Denver Model",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard community care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": "24 Months",
        "sex": "ALL",
        "summary": "12 Months to 24 Months"
      },
      "enrollment_count": 118,
      "start_date": "2008-04",
      "completion_date": "2013-12",
      "has_results": true,
      "last_update_posted_date": "2020-02-17",
      "last_synced_at": "2026-09-02T06:13:04.574Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00698997"
    },
    {
      "nct_id": "NCT06005285",
      "title": "Examining the Effectiveness of the Early Start Denver Model in Community Programs Serving Young Autism",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autism"
      ],
      "interventions": [
        {
          "name": "Early Start Denver Model (ESDM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Early Intensive Behavioral Intervention (EIBI)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Months and older"
      },
      "enrollment_count": 600,
      "start_date": "2024-03-01",
      "completion_date": "2028-06-01",
      "has_results": false,
      "last_update_posted_date": "2025-12-05",
      "last_synced_at": "2026-09-02T06:13:04.574Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06005285"
    },
    {
      "nct_id": "NCT03592654",
      "title": "Pilot Study: A Telehealth Intervention for Caregivers of Infants With Early Signs of Autism Spectrum Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autism Spectrum Disorder",
        "Developmental Delay"
      ],
      "interventions": [
        {
          "name": "infant telehelp",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Months",
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "5 Months to 12 Months"
      },
      "enrollment_count": 12,
      "start_date": "2018-07-01",
      "completion_date": "2019-10-01",
      "has_results": false,
      "last_update_posted_date": "2020-09-04",
      "last_synced_at": "2026-09-02T06:13:04.574Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03592654"
    }
  ]
}