{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Eccentric+leg+extension",
    "query": {
      "intervention": "Eccentric leg extension"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Eccentric+leg+extension&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-24T02:36:25.611Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05934708",
      "title": "Examining the Role of Female Endogenous Sex Hormones in Eccentric Exercise",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Inflammatory Response"
      ],
      "interventions": [
        {
          "name": "Eccentric leg extension",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 35 Years · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2025-03-07",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2026-03-25",
      "last_synced_at": "2026-09-24T02:36:25.611Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05934708"
    },
    {
      "nct_id": "NCT01988155",
      "title": "Eccentric Exercise Versus Eccentric Exercise and Astym for Insertional Achilles Tendinopathy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insertional Achilles Tendinopathy"
      ],
      "interventions": [
        {
          "name": "Eccentric Exercise",
          "type": "OTHER"
        },
        {
          "name": "Astym",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Indiana University Health Ball Memorial Hospital Rehabiliation Services",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 16,
      "start_date": "2013-12",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2016-02-23",
      "last_synced_at": "2026-09-24T02:36:25.611Z",
      "location_count": 1,
      "location_summary": "Muncie, Indiana",
      "locations": [
        {
          "city": "Muncie",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01988155"
    },
    {
      "nct_id": "NCT01245283",
      "title": "Resistance Exercise and Knee Osteoarthritis Pain, Functional Impairment and Cartilage Turnover",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "normal activities and clinical care",
          "type": "OTHER"
        },
        {
          "name": "Concentric Focused Resistance Exercise",
          "type": "OTHER"
        },
        {
          "name": "Eccentric Focused Resistance Exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "60 Years to 85 Years"
      },
      "enrollment_count": 90,
      "start_date": "2010-11",
      "completion_date": "2013-06",
      "has_results": true,
      "last_update_posted_date": "2014-12-05",
      "last_synced_at": "2026-09-24T02:36:25.611Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01245283"
    },
    {
      "nct_id": "NCT04162262",
      "title": "Effects of Exercise Versus Exercise and Instrument-Assisted Soft Tissue Mobilization for Plantar Fasciopathy Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Plantar Fascitis"
      ],
      "interventions": [
        {
          "name": "Instrumental-assisted soft tissue mobilization (IASTM)",
          "type": "OTHER"
        },
        {
          "name": "High-Load Strength Training",
          "type": "OTHER"
        },
        {
          "name": "Plantar Flexor and Gastrocnemius Stretching",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Texas Tech University Health Sciences Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 83,
      "start_date": "2019-10-24",
      "completion_date": "2021-01-15",
      "has_results": false,
      "last_update_posted_date": "2021-02-05",
      "last_synced_at": "2026-09-24T02:36:25.611Z",
      "location_count": 1,
      "location_summary": "Lubbock, Texas",
      "locations": [
        {
          "city": "Lubbock",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04162262"
    },
    {
      "nct_id": "NCT01826071",
      "title": "Comparison of Three Treatments for Lower Extremity Apophysitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osgood-Schlatter Syndrome (OSS)",
        "Sinding-Larson and Johansson Syndrome (SLJ)",
        "Sever's Disease",
        "Apophysitis"
      ],
      "interventions": [
        {
          "name": "Static Stretch",
          "type": "OTHER"
        },
        {
          "name": "Active Elongation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Ann & Robert H Lurie Children's Hospital of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "8 Years to 17 Years"
      },
      "enrollment_count": 129,
      "start_date": "2012-10",
      "completion_date": "2023-10",
      "has_results": false,
      "last_update_posted_date": "2025-02-10",
      "last_synced_at": "2026-09-24T02:36:25.611Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01826071"
    },
    {
      "nct_id": "NCT00924625",
      "title": "The Use of Neuromuscular Electrical Stimulation to Reverse Muscle Atrophy in Patients With Rheumatoid Arthritis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rheumatoid Arthritis"
      ],
      "interventions": [
        {
          "name": "Neuromuscular electrical stimulation",
          "type": "OTHER"
        },
        {
          "name": "Volitional exercises",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 64,
      "start_date": "2009-06",
      "completion_date": "2014-02",
      "has_results": false,
      "last_update_posted_date": "2014-09-10",
      "last_synced_at": "2026-09-24T02:36:25.611Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00924625"
    },
    {
      "nct_id": "NCT07424352",
      "title": "Knee Osteoarthritis Rehabilitation Through Rotational Inertia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Arthritis, Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Eccentric resistance training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 60,
      "start_date": "2025-08-20",
      "completion_date": "2029-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-20",
      "last_synced_at": "2026-09-24T02:36:25.611Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07424352"
    },
    {
      "nct_id": "NCT02098096",
      "title": "Negative Work Exercise for the Treatment of Knee Arthritis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Arthritis"
      ],
      "interventions": [
        {
          "name": "Negative Work",
          "type": "OTHER"
        },
        {
          "name": "Stretching",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Washington D.C. Veterans Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "70 Years",
        "sex": "MALE",
        "summary": "50 Years to 70 Years · Male only"
      },
      "enrollment_count": 54,
      "start_date": "2014-03",
      "completion_date": "2019-11",
      "has_results": false,
      "last_update_posted_date": "2018-09-20",
      "last_synced_at": "2026-09-24T02:36:25.611Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02098096"
    },
    {
      "nct_id": "NCT00761163",
      "title": "The Body's Response to Aerobic Versus Resistance Exercise",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Exercise"
      ],
      "interventions": [
        {
          "name": "Resistance Exercise",
          "type": "OTHER"
        },
        {
          "name": "Aerobic Exercise",
          "type": "OTHER"
        },
        {
          "name": "Control (Non-exercise)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Purdue University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2007-02",
      "completion_date": "2008-11",
      "has_results": false,
      "last_update_posted_date": "2013-01-17",
      "last_synced_at": "2026-09-24T02:36:25.611Z",
      "location_count": 1,
      "location_summary": "West Lafayette, Indiana",
      "locations": [
        {
          "city": "West Lafayette",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00761163"
    },
    {
      "nct_id": "NCT01058213",
      "title": "Nurse Managed Sequential Strength Training and Bicycle Training in Chronic Obstructive Pulmonary Disease (COPD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease"
      ],
      "interventions": [
        {
          "name": "Resistance training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Aerobic training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "46 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "46 Years and older"
      },
      "enrollment_count": 354,
      "start_date": "2008-11",
      "completion_date": "2013-05",
      "has_results": false,
      "last_update_posted_date": "2013-12-18",
      "last_synced_at": "2026-09-24T02:36:25.611Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01058213"
    }
  ]
}