{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Edwards+SAPIEN+3+TAVR+System",
    "query": {
      "intervention": "Edwards SAPIEN 3 TAVR System"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 5,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-08T23:09:17.060Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04722250",
      "title": "SMall Annuli Randomized To Evolut™ or SAPIEN™ Trial",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Symptomatic Aortic Stenosis",
        "Aortic Valve Stenosis",
        "Aortic Valve Replacement"
      ],
      "interventions": [
        {
          "name": "Medtronic Evolut PRO, Evolut PRO+ or Evolut FX (where commercially available) TAV Systems",
          "type": "DEVICE"
        },
        {
          "name": "Edwards SAPIEN 3 or SAPIEN 3 Ultra THV Systems",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic Cardiovascular",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1103,
      "start_date": "2021-04-02",
      "completion_date": "2027-12",
      "has_results": true,
      "last_update_posted_date": "2026-06-02",
      "last_synced_at": "2026-09-08T23:09:17.060Z",
      "location_count": 61,
      "location_summary": "La Jolla, California • Los Angeles, California • San Francisco, California + 47 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Thousand Oaks",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04722250"
    },
    {
      "nct_id": "NCT03225001",
      "title": "PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - Nested Registry 3/Valve-in-Valve",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Stenosis",
        "Cardiomyopathy, Hypertrophic"
      ],
      "interventions": [
        {
          "name": "Edwards SAPIEN XT transcatheter valve, Model 9300TFX",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Edwards Lifesciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 197,
      "start_date": "2012-06-11",
      "completion_date": "2020-10-28",
      "has_results": true,
      "last_update_posted_date": "2021-03-09",
      "last_synced_at": "2026-09-08T23:09:17.060Z",
      "location_count": 46,
      "location_summary": "La Jolla, California • Los Angeles, California • Sacramento, California + 39 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03225001"
    },
    {
      "nct_id": "NCT02675114",
      "title": "PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Stenosis"
      ],
      "interventions": [
        {
          "name": "SAVR",
          "type": "PROCEDURE"
        },
        {
          "name": "SAPIEN 3 THV",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Edwards Lifesciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1000,
      "start_date": "2016-03",
      "completion_date": "2029-12",
      "has_results": true,
      "last_update_posted_date": "2026-01-14",
      "last_synced_at": "2026-09-08T23:09:17.060Z",
      "location_count": 68,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Burlingame, California + 59 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Burlingame",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02675114"
    },
    {
      "nct_id": "NCT03003299",
      "title": "PARTNER 3 Trial - Aortic Valve-in-Valve",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Stenosis",
        "Aortic Stenosis, Severe"
      ],
      "interventions": [
        {
          "name": "Edwards SAPIEN 3/SAPIEN 3 Ultra THV",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Edwards Lifesciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 125,
      "start_date": "2017-01-05",
      "completion_date": "2038-04",
      "has_results": false,
      "last_update_posted_date": "2024-05-10",
      "last_synced_at": "2026-09-08T23:09:17.060Z",
      "location_count": 50,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Sacramento, California + 43 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03003299"
    },
    {
      "nct_id": "NCT03735667",
      "title": "ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Stenosis"
      ],
      "interventions": [
        {
          "name": "ACURATE neo2™ Transfemoral TAVR System",
          "type": "DEVICE"
        },
        {
          "name": "Medtronic CoreValve TAVR System",
          "type": "DEVICE"
        },
        {
          "name": "Edwards SAPIEN 3 TAVR System",
          "type": "DEVICE"
        },
        {
          "name": "ACURATE Prime™ Transfemoral TAVR System XL",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1948,
      "start_date": "2019-06-10",
      "completion_date": "2029-09",
      "has_results": true,
      "last_update_posted_date": "2026-05-04",
      "last_synced_at": "2026-09-08T23:09:17.060Z",
      "location_count": 69,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 58 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03735667"
    }
  ]
}