{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Empagliflozin+Placebo&page=3", "query": { "intervention": "Empagliflozin Placebo", "page": 3 }, "page_size": 10 }, "pagination": { "page": 3, "page_size": 10, "total_count": 78, "total_pages": 8, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Empagliflozin+Placebo&page=4&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Empagliflozin+Placebo&page=2&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-17T06:40:04.967Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05553938", "title": "Effects of Acute and Chronic Empagliflozin Heart Failure", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Heart Failure" ], "interventions": [ { "name": "Empagliflozin 10 mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2023-08-04", "completion_date": "2026-08-14", "has_results": false, "last_update_posted_date": "2026-07-02", "last_synced_at": "2026-10-17T06:40:04.967Z", "location_count": 2, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" }, { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT05553938" }, { "nct_id": "NCT05057806", "title": "SGLT2 Inhibitors, Ketones, and Cardiovascular Benefit Research Plan", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Type2 Diabetes", "Heart Failure With Preserved Ejection Fraction" ], "interventions": [ { "name": "Empagliflozin 25 MG", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The University of Texas Health Science Center at San Antonio", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 30, "start_date": "2021-01-13", "completion_date": "2027-03-31", "has_results": false, "last_update_posted_date": "2026-04-06", "last_synced_at": "2026-10-17T06:40:04.967Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05057806" }, { "nct_id": "NCT05512130", "title": "Sodium-Glucose Cotransporter-2 Inhibitors: A Potential Novel Treatment for Epilepsy", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Epilepsy" ], "interventions": [ { "name": "Empagliflozin 25 mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 18, "start_date": "2022-08-17", "completion_date": "2023-06-30", "has_results": false, "last_update_posted_date": "2022-08-23", "last_synced_at": "2026-10-17T06:40:04.967Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT05512130" }, { "nct_id": "NCT05726032", "title": "Empagliflozin in Patients With Cirrhosis and Ascites", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cirrhosis", "Liver Failure" ], "interventions": [ { "name": "Empagliflozin 10 MG", "type": "DRUG" }, { "name": "Matching Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2023-09-11", "completion_date": "2026-12-01", "has_results": false, "last_update_posted_date": "2026-09-14", "last_synced_at": "2026-10-17T06:40:04.967Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT05726032" }, { "nct_id": "NCT01159600", "title": "Efficacy and Safety Study With Empagliflozin (BI 10773) vs. Placebo as add-on to Metformin or Metformin Plus Sulfonylurea Over 24 Weeks in Patients With Type 2 Diabetes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Diabetes Mellitus, Type 2" ], "interventions": [ { "name": "Placebo identical to BI 10773 high dose", "type": "DRUG" }, { "name": "Placebo identical to BI 10773 low dose", "type": "DRUG" }, { "name": "BI 10773", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1504, "start_date": "2010-07", "completion_date": null, "has_results": true, "last_update_posted_date": "2014-06-17", "last_synced_at": "2026-10-17T06:40:04.967Z", "location_count": 25, "location_summary": "Birmingham, Alabama • Tempe, Arizona • Huntington Park, California + 21 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Tempe", "state": "Arizona" }, { "city": "Huntington Park", "state": "California" }, { "city": "Huntington Park", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01159600" }, { "nct_id": "NCT04509674", "title": "EMPACT-MI: A Study to Test Whether Empagliflozin Can Lower the Risk of Heart Failure and Death in People Who Had a Heart Attack (Myocardial Infarction)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Myocardial Infarction" ], "interventions": [ { "name": "Empagliflozin", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 6522, "start_date": "2020-12-16", "completion_date": "2023-11-05", "has_results": true, "last_update_posted_date": "2025-01-07", "last_synced_at": "2026-10-17T06:40:04.967Z", "location_count": 85, "location_summary": "Alexander City, Alabama • Birmingham, Alabama • Huntsville, Alabama + 75 more", "locations": [ { "city": "Alexander City", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Gilbert", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04509674" }, { "nct_id": "NCT03429543", "title": "Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Diabetes Mellitus, Type 2" ], "interventions": [ { "name": "Metformin", "type": "DRUG" }, { "name": "Insulin", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Linagliptin", "type": "DRUG" }, { "name": "Empagliflozin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "10 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "10 Years to 17 Years" }, "enrollment_count": 175, "start_date": "2018-03-20", "completion_date": "2023-05-31", "has_results": true, "last_update_posted_date": "2024-02-23", "last_synced_at": "2026-10-17T06:40:04.967Z", "location_count": 44, "location_summary": "Phoenix, Arizona • Tucson, Arizona • Orange, California + 39 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Orange", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03429543" }, { "nct_id": "NCT03152552", "title": "A Dose Finding Study to Assess the Effect of LIK066 Compared to Placebo or Empagliflozin in Patients With Type 2 Diabetes Mellitus and Heart Failure", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Diabetes Mellitus and Heart Failure" ], "interventions": [ { "name": "LIK066", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Empagliflozin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 125, "start_date": "2017-07-25", "completion_date": "2018-06-06", "has_results": true, "last_update_posted_date": "2019-08-28", "last_synced_at": "2026-10-17T06:40:04.967Z", "location_count": 21, "location_summary": "Huntsville, Alabama • Carmichael, California • Concord, California + 18 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Carmichael", "state": "California" }, { "city": "Concord", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "Northridge", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03152552" }, { "nct_id": "NCT06506422", "title": "Empagliflozin Reversal of Arterial StiffnEss in Aging", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Aging", "Arterial Stiffness" ], "interventions": [ { "name": "Empagliflozin 10 MG", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Missouri-Columbia", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "60 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "60 Years to 80 Years" }, "enrollment_count": 80, "start_date": "2024-08-18", "completion_date": "2029-02-28", "has_results": false, "last_update_posted_date": "2026-02-06", "last_synced_at": "2026-10-17T06:40:04.967Z", "location_count": 1, "location_summary": "Columbia, Missouri", "locations": [ { "city": "Columbia", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT06506422" }, { "nct_id": "NCT01370005", "title": "12 Week Efficacy and Safety Study of Empagliflozin (BI 10773) in Hypertensive Patients With Type 2 Diabetes Mellitus", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Diabetes Mellitus, Type 2", "Hypertension" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "BI 10773", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 825, "start_date": "2011-06", "completion_date": "2012-07", "has_results": true, "last_update_posted_date": "2016-02-22", "last_synced_at": "2026-10-17T06:40:04.967Z", "location_count": 35, "location_summary": "Huntsville, Alabama • Phoenix, Arizona • Lincoln, California + 29 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Lincoln", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "Long Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01370005" } ] }