{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Energy+balance",
    "query": {
      "intervention": "Energy balance"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 219,
    "total_pages": 22,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Energy+balance&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T01:55:03.179Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01354600",
      "title": "Effects of Positive Energy Balance and Exercise on Appetite Hormones in Sedentary Men and Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Appetite and General Nutritional Disorders"
      ],
      "interventions": [
        {
          "name": "Exercise or Sedentary",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 13,
      "start_date": "2009-05",
      "completion_date": "2012-02",
      "has_results": false,
      "last_update_posted_date": "2013-07-23",
      "last_synced_at": "2026-09-03T01:55:03.179Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01354600"
    },
    {
      "nct_id": "NCT02103582",
      "title": "Quit and Fit: A Tobacco Cessation and Energy Balance Pilot for African Americans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Georgetown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "69 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 69 Years · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2013-04",
      "completion_date": "2017-11",
      "has_results": false,
      "last_update_posted_date": "2017-11-29",
      "last_synced_at": "2026-09-03T01:55:03.179Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02103582"
    },
    {
      "nct_id": "NCT03329963",
      "title": "Lifestyle Intervention to Improve Bone Quality",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Healthy Lifestyle Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Lifestyle Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "65 Years to 85 Years"
      },
      "enrollment_count": 120,
      "start_date": "2017-11-09",
      "completion_date": "2023-01-16",
      "has_results": false,
      "last_update_posted_date": "2025-06-06",
      "last_synced_at": "2026-09-03T01:55:03.179Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03329963"
    },
    {
      "nct_id": "NCT06284681",
      "title": "Weight Inclusive and Adaptive Strategies to Enhance Cardiometabolic Health in Black Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Prehypertension",
        "Hypertension",
        "PreDiabetes",
        "Type 2 Diabetes",
        "Dyslipidemia"
      ],
      "interventions": [
        {
          "name": "Weight-focused health coaching",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Weight-neutral health coaching",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Intensify lifestyle approach",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Augment with enhanced medical management",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 41,
      "start_date": "2024-10-01",
      "completion_date": "2026-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-09-03T01:55:03.179Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06284681"
    },
    {
      "nct_id": "NCT03872375",
      "title": "Calorie Restriction and Brain Function in Mild Cognitive Impairment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Meal-Replacement Therapy",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Dietary Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "BEHAVIORAL"
      ],
      "sponsor": "Iowa State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "70 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "70 Years to 85 Years"
      },
      "enrollment_count": 96,
      "start_date": "2019-05-08",
      "completion_date": "2021-12-31",
      "has_results": false,
      "last_update_posted_date": "2022-03-31",
      "last_synced_at": "2026-09-03T01:55:03.179Z",
      "location_count": 2,
      "location_summary": "Ames, Iowa • Iowa City, Iowa",
      "locations": [
        {
          "city": "Ames",
          "state": "Iowa"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03872375"
    },
    {
      "nct_id": "NCT03505983",
      "title": "Criteria for Advanced Prosthetic Foot Prescription",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prosthesis User",
        "Amputation; Traumatic, Limb, Lower"
      ],
      "interventions": [
        {
          "name": "ESR Prosthetic Foot First",
          "type": "DEVICE"
        },
        {
          "name": "Articulating ESR Prosthetic Foot First",
          "type": "DEVICE"
        },
        {
          "name": "Powered Prosthetic Foot First",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VA New York Harbor Healthcare System",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 91,
      "start_date": "2018-03-07",
      "completion_date": "2026-09-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-10",
      "last_synced_at": "2026-09-03T01:55:03.179Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03505983"
    },
    {
      "nct_id": "NCT07132788",
      "title": "Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pulmonary Hypertension"
      ],
      "interventions": [
        {
          "name": "blood draw",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Short Performance Physical Battery",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Grip strength test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Six minute walk test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Chest CT scan",
          "type": "RADIATION"
        },
        {
          "name": "Dual-Energy X-ray Absorptiometry Scan",
          "type": "RADIATION"
        },
        {
          "name": "Activity monitoring",
          "type": "BEHAVIORAL"
        },
        {
          "name": "24 hour diet recall",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Echocardiogram",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Quality of Life Questionnaire (emPHasis 10)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "International Physical Activity Questionnaire Short Form (IPAQ-SF)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "RADIATION",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2025-05-01",
      "completion_date": "2029-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-09-01",
      "last_synced_at": "2026-09-03T01:55:03.179Z",
      "location_count": 2,
      "location_summary": "Philadelphia, Pennsylvania • Providence, Rhode Island",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07132788"
    },
    {
      "nct_id": "NCT00653484",
      "title": "Energy Balance Interventions for Colorectal Cancer Prevention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colorectal Cancer",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Physical Activity",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Energy Restriction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Physical Activity and Energy Restriction",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2008-03",
      "completion_date": "2013-06",
      "has_results": false,
      "last_update_posted_date": "2013-12-17",
      "last_synced_at": "2026-09-03T01:55:03.179Z",
      "location_count": 3,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00653484"
    },
    {
      "nct_id": "NCT07227363",
      "title": "Symptoms of Polycystic Ovarian Syndrome Ameliorated by Keto-Adaptation Pilot",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "PCOS (Polycystic Ovary Syndrome)"
      ],
      "interventions": [
        {
          "name": "Ketogenic diet",
          "type": "OTHER"
        },
        {
          "name": "Exogenous Ketone Supplement",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2026-12-01",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-05-08",
      "last_synced_at": "2026-09-03T01:55:03.179Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07227363"
    },
    {
      "nct_id": "NCT02664441",
      "title": "Energy Balance & Weight Loss in Craniopharyngioma-related or Other Hypothalamic Tumors in Hypothalamic Obesity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Hypothalamic Obesity"
      ],
      "interventions": [
        {
          "name": "Exenatide",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Seattle Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "10 Years to 25 Years"
      },
      "enrollment_count": 42,
      "start_date": "2016-03",
      "completion_date": "2020-07-31",
      "has_results": true,
      "last_update_posted_date": "2022-05-05",
      "last_synced_at": "2026-09-03T01:55:03.179Z",
      "location_count": 3,
      "location_summary": "Minneapolis, Minnesota • Nashville, Tennessee • Seattle, Washington",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02664441"
    }
  ]
}