{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Enhanced+Weight+Loss+Intervention",
    "query": {
      "intervention": "Enhanced Weight Loss Intervention"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 97,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Enhanced+Weight+Loss+Intervention&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T23:49:35.726Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00846040",
      "title": "Reduced Carbohydrate Versus Fat in Obese Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Reduced fat diet",
          "type": "OTHER"
        },
        {
          "name": "Reduced carbohydrate diet",
          "type": "OTHER"
        },
        {
          "name": "Drug: f-18 fallypride",
          "type": "DRUG"
        },
        {
          "name": "fMRI",
          "type": "DEVICE"
        },
        {
          "name": "PET",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 43,
      "start_date": "2009-02-13",
      "completion_date": "2014-10-20",
      "has_results": true,
      "last_update_posted_date": "2021-04-15",
      "last_synced_at": "2026-09-04T23:49:35.726Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00846040"
    },
    {
      "nct_id": "NCT04757519",
      "title": "Enhanced DPP-GLB to Promote Weight Loss Among Nonresponders in a Community-Based Lifestyle Intervention.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes"
      ],
      "interventions": [
        {
          "name": "DPP-GLB Standard",
          "type": "BEHAVIORAL"
        },
        {
          "name": "DPP-GLB Enhanced",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Lovoria Williams",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 403,
      "start_date": "2021-02-18",
      "completion_date": "2026-04-17",
      "has_results": true,
      "last_update_posted_date": "2026-06-24",
      "last_synced_at": "2026-09-04T23:49:35.726Z",
      "location_count": 21,
      "location_summary": "Frankfort, Kentucky • Lexington, Kentucky • Louisville, Kentucky + 2 more",
      "locations": [
        {
          "city": "Frankfort",
          "state": "Kentucky"
        },
        {
          "city": "Frankfort",
          "state": "Kentucky"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04757519"
    },
    {
      "nct_id": "NCT05775497",
      "title": "Optimizing an Online Behavioral Weight Loss Intervention and Novel Culturally Tailored Components for Sexual Minority Women",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Behavioral weight loss intervention (Online; Rx Weight Loss)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Minority stress intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Social support intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Negative body image intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The Miriam Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 70 Years · Female only"
      },
      "enrollment_count": 88,
      "start_date": "2024-05-01",
      "completion_date": "2025-12-29",
      "has_results": false,
      "last_update_posted_date": "2024-12-27",
      "last_synced_at": "2026-09-04T23:49:35.726Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05775497"
    },
    {
      "nct_id": "NCT03874988",
      "title": "Building an Evidence Base for Weight Loss Strategies Among Those With Chronic SCI-The GLB-SCI+",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries",
        "Obesity",
        "Weight Loss",
        "Diet Modification"
      ],
      "interventions": [
        {
          "name": "Portion-Controlled Meals",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced Self-Monitoring",
          "type": "BEHAVIORAL"
        },
        {
          "name": "GLB-SCI+",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Baylor Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2019-06-01",
      "completion_date": "2022-06-15",
      "has_results": false,
      "last_update_posted_date": "2025-10-15",
      "last_synced_at": "2026-09-04T23:49:35.726Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03874988"
    },
    {
      "nct_id": "NCT07387393",
      "title": "To Test the Effectiveness and Implementation Approach of a 3-month PILI Pasifika Program Lifestyle Program With Components of Social Determinants of Health Activities in Real-world Settings (Clinical and Non-clinical Settings) Across 3 Years",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiometabolic Conditions",
        "Hypertension (HTN)",
        "Dyslipidemia",
        "Pre-diabetes",
        "Type 2 Diabetes Mellitus (T2DM)",
        "Overweight (BMI > 25)",
        "Weight Loss Trial"
      ],
      "interventions": [
        {
          "name": "PILI (Partnership for Improving Lifestyle Intervention) Pasifika Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Hawaii",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2026-05-01",
      "completion_date": "2028-10-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-09",
      "last_synced_at": "2026-09-04T23:49:35.726Z",
      "location_count": 2,
      "location_summary": "Fayetteville, Arkansas • Honolulu, Hawaii",
      "locations": [
        {
          "city": "Fayetteville",
          "state": "Arkansas"
        },
        {
          "city": "Honolulu",
          "state": "Hawaii"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07387393"
    },
    {
      "nct_id": "NCT04246827",
      "title": "Rheumatoid Arthritis Coping Enhancement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rheumatoid Arthritis",
        "Obesity",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Enhanced Lifestyle Weight Management",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 50,
      "start_date": "2009-07-07",
      "completion_date": "2011-09-30",
      "has_results": false,
      "last_update_posted_date": "2020-01-29",
      "last_synced_at": "2026-09-04T23:49:35.726Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04246827"
    },
    {
      "nct_id": "NCT02466061",
      "title": "TREC Lifestyle Beyond Cancer Study in Endometrial Cancer Survivors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Endometrial Cancer"
      ],
      "interventions": [
        {
          "name": "Telemedicine Weight Management plus Wi-Fi Scale (Arm A)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Text for Diet (Text4Diet) Group (Arm B)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced Usual Care Group (Arm C)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Fred Hutchinson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 207,
      "start_date": "2014-07",
      "completion_date": "2016-06",
      "has_results": false,
      "last_update_posted_date": "2016-06-02",
      "last_synced_at": "2026-09-04T23:49:35.726Z",
      "location_count": 3,
      "location_summary": "Boston, Massachusetts • St Louis, Missouri • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02466061"
    },
    {
      "nct_id": "NCT00771095",
      "title": "Pounds Off Digitally Study: A Podcasting Weight Loss Intervention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Weight Loss"
      ],
      "interventions": [
        {
          "name": "podcasting",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 94,
      "start_date": "2008-01",
      "completion_date": "2008-06",
      "has_results": false,
      "last_update_posted_date": "2008-10-10",
      "last_synced_at": "2026-09-04T23:49:35.726Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00771095"
    },
    {
      "nct_id": "NCT03860558",
      "title": "Impact of Metabolic Health on Sperm Epigenetic Marks in Humans",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overweight",
        "Type 2 Diabetes Mellitus",
        "Type 1 Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Lifestyle Intervention",
          "type": "OTHER"
        },
        {
          "name": "No Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Joslin Diabetes Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "MALE",
        "summary": "18 Years to 65 Years · Male only"
      },
      "enrollment_count": 40,
      "start_date": "2018-05-01",
      "completion_date": "2026-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-06",
      "last_synced_at": "2026-09-04T23:49:35.726Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03860558"
    },
    {
      "nct_id": "NCT05072587",
      "title": "Dietary Oxysterols and β-Cell Function Among African Americans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 2 Diabetes"
      ],
      "interventions": [
        {
          "name": "Plant-based diet with no oxysterols",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard ADA Diet (SADA)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Morehouse School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2021-07-01",
      "completion_date": "2023-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-17",
      "last_synced_at": "2026-09-04T23:49:35.726Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05072587"
    }
  ]
}