{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Entecavir+%28ETV%29&page=2", "query": { "intervention": "Entecavir (ETV)", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 42, "total_pages": 5, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Entecavir+%28ETV%29&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Entecavir+%28ETV%29&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-02T16:14:02.921Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00096785", "title": "Comparative Trial of Entecavir Versus Adefovir in the Treatment of Chronic Hepatitis B Infection", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hepatitis B", "Chronic Disease" ], "interventions": [ { "name": "entecavir", "type": "DRUG" }, { "name": "adefovir", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": null, "sex": "ALL", "summary": "16 Years and older" }, "enrollment_count": 69, "start_date": "2004-12", "completion_date": "2008-04", "has_results": true, "last_update_posted_date": "2010-08-10", "last_synced_at": "2026-10-02T16:14:02.921Z", "location_count": 11, "location_summary": "San Diego, California • San Francisco, California • Torrance, California + 7 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Torrance", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "North Miami Beach", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00096785" }, { "nct_id": "NCT03361956", "title": "An Efficacy, Safety, and Pharmacokinetics Study of JNJ-56136379 in Participants With Chronic Hepatitis B Virus Infection", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hepatitis B" ], "interventions": [ { "name": "JNJ-56136379", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "NA (ETV or TDF)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Sciences Ireland UC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 232, "start_date": "2018-02-13", "completion_date": "2020-08-13", "has_results": true, "last_update_posted_date": "2022-11-17", "last_synced_at": "2026-10-02T16:14:02.921Z", "location_count": 7, "location_summary": "Bakersfield, California • Orlando, Florida • Chicago, Illinois + 4 more", "locations": [ { "city": "Bakersfield", "state": "California" }, { "city": "Orlando", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" }, { "city": "New Orleans", "state": "Louisiana" }, { "city": "Hillsborough", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT03361956" }, { "nct_id": "NCT01369199", "title": "Combination Entecavir and Peginterferon Therapy in HBeAg-Positive Immune-Tolerant Adults With Chronic Hepatitis B", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hepatitis B" ], "interventions": [ { "name": "Entecavir and peginterferon", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 28, "start_date": "2012-05", "completion_date": "2017-02-14", "has_results": true, "last_update_posted_date": "2022-05-26", "last_synced_at": "2026-10-02T16:14:02.921Z", "location_count": 20, "location_summary": "Los Angeles, California • San Francisco, California • Honolulu, Hawaii + 11 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Honolulu", "state": "Hawaii" } ], "official_url": "https://clinicaltrials.gov/study/NCT01369199" }, { "nct_id": "NCT02452528", "title": "Study of ARC-520 in Participants With Hepatitis B Virus e Antigen (HBeAg) Positive Chronic Hepatitis B Virus", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Hepatitis B" ], "interventions": [ { "name": "ARC-520", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Entecavir", "type": "DRUG" }, { "name": "Tenofovir", "type": "DRUG" }, { "name": "diphenhydramine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Arrowhead Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 4, "start_date": "2015-08", "completion_date": "2016-12", "has_results": true, "last_update_posted_date": "2025-11-03", "last_synced_at": "2026-10-02T16:14:02.921Z", "location_count": 4, "location_summary": "San Francisco, California • Miami, Florida • New York, New York + 1 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "New York", "state": "New York" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02452528" }, { "nct_id": "NCT01204762", "title": "Dose Ranging Study of Pegylated Interferon Lambda in Patients With Hepatitis B and Positive for the Hepatitis B e Antigen", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hepatitis B Virus" ], "interventions": [ { "name": "pegIFN", "type": "DRUG" }, { "name": "pegIFNα-2a", "type": "DRUG" }, { "name": "PegIFN lambda", "type": "DRUG" }, { "name": "Entecavir", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 197, "start_date": "2010-11", "completion_date": "2013-12", "has_results": false, "last_update_posted_date": "2015-10-09", "last_synced_at": "2026-10-02T16:14:02.921Z", "location_count": 13, "location_summary": "Anaheim, California • Garden Grove, California • Sacramento, California + 9 more", "locations": [ { "city": "Anaheim", "state": "California" }, { "city": "Garden Grove", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT01204762" }, { "nct_id": "NCT03780543", "title": "A Study of ABI-H0731 + Nucleos(t)Ide as Finite Treatment for Chronic Hepatitis B Patients", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Hepatitis B" ], "interventions": [ { "name": "standard of care (SOC) Nucleoside reverse transcriptase inhibitor (NrtI)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Assembly Biosciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "71 Years", "sex": "ALL", "summary": "18 Years to 71 Years" }, "enrollment_count": 92, "start_date": "2018-12-20", "completion_date": "2021-04-26", "has_results": true, "last_update_posted_date": "2023-04-19", "last_synced_at": "2026-10-02T16:14:02.921Z", "location_count": 17, "location_summary": "Beverly Hills, California • Coronado, California • Los Angeles, California + 10 more", "locations": [ { "city": "Beverly Hills", "state": "California" }, { "city": "Coronado", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03780543" }, { "nct_id": "NCT03577171", "title": "A Study Evaluating ABI-H0731+ Entecavir vs Entecavir Alone for the Treatment of Viremic HBeAg-positive Participants With Chronic Hepatitis B Virus Infection (cHBV)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Hepatitis B" ], "interventions": [ { "name": "ABI-H0731", "type": "DRUG" }, { "name": "SOC ETV", "type": "DRUG" }, { "name": "Placebo Oral Tablet", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Assembly Biosciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 25, "start_date": "2018-06-19", "completion_date": "2019-06-21", "has_results": true, "last_update_posted_date": "2021-01-28", "last_synced_at": "2026-10-02T16:14:02.921Z", "location_count": 7, "location_summary": "Coronado, California • Los Angeles, California • San Diego, California + 4 more", "locations": [ { "city": "Coronado", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT03577171" }, { "nct_id": "NCT00036608", "title": "A Phase III Study of Entecavir vs Lamivudine in Chronic Hepatitis B Subjects With Incomplete Response to Lamivudine", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Hepatitis B" ], "interventions": [ { "name": "Entecavir", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": null, "sex": "ALL", "summary": "16 Years and older" }, "enrollment_count": null, "start_date": "2002-01", "completion_date": "2005-02", "has_results": false, "last_update_posted_date": "2011-04-14", "last_synced_at": "2026-10-02T16:14:02.921Z", "location_count": 39, "location_summary": "Birmingham, Alabama • Tucson, Arizona • La Jolla, California + 31 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00036608" }, { "nct_id": "NCT05404919", "title": "Utilization of Hepatitis B Virus NAT+ Donors for Hepatitis B Vaccinated Lung Transplant Candidates", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Lung Transplant", "Hepatitis B" ], "interventions": [ { "name": "Hepatitis B Immune Globulin and entecavir, tenofovir disoproxil, or tenofovir alafenamide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 0, "start_date": "2022-09-06", "completion_date": "2024-08-01", "has_results": false, "last_update_posted_date": "2024-08-06", "last_synced_at": "2026-10-02T16:14:02.921Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT05404919" }, { "nct_id": "NCT01715987", "title": "Tubular Function in Asian-American Patients Receiving TDF or ETV for HBV Treatment", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Hepatitis B" ], "interventions": [ { "name": "Tenofovir Disoproxil Fumarate", "type": "DRUG" }, { "name": "Entecavir", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "New Discovery LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 48, "start_date": "2012-10", "completion_date": "2016-05", "has_results": false, "last_update_posted_date": "2017-09-06", "last_synced_at": "2026-10-02T16:14:02.921Z", "location_count": 2, "location_summary": "Los Angeles, California • New York, New York", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01715987" } ] }