{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Estrace%C2%AE+Cream", "query": { "intervention": "Estrace® Cream" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 6, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-17T01:49:09.725Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05645393", "title": "Effect of Estradiol Topical Products", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Menopause" ], "interventions": [ { "name": "topical estrogen product", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Maryland, Baltimore", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "45 Years", "maximum_age": "65 Years", "sex": "FEMALE", "summary": "45 Years to 65 Years · Female only" }, "enrollment_count": 4, "start_date": "2024-06-05", "completion_date": "2025-03-30", "has_results": false, "last_update_posted_date": "2025-05-20", "last_synced_at": "2026-09-17T01:49:09.725Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT05645393" }, { "nct_id": "NCT00167921", "title": "Study Comparing Premarin® Vaginal Cream Versus Premarin® Oral Tablets in Atrophic Vaginitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Atrophic Vaginitis" ], "interventions": [ { "name": "Premarin® Vaginal Cream", "type": "DRUG" }, { "name": "Premarin® oral tablets", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Wyeth is now a wholly owned subsidiary of Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "45 Years", "maximum_age": "80 Years", "sex": "FEMALE", "summary": "45 Years to 80 Years · Female only" }, "enrollment_count": 24, "start_date": "2005-10", "completion_date": null, "has_results": false, "last_update_posted_date": "2007-05-28", "last_synced_at": "2026-09-17T01:49:09.725Z", "location_count": 2, "location_summary": "Miami, Florida • Baltimore, Maryland", "locations": [ { "city": "Miami", "state": "Florida" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00167921" }, { "nct_id": "NCT02524769", "title": "The Estrogen Impact on Overactive Bladder Syndrome: Female Pelvic Floor Microbiomes and Antimicrobial Peptides", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Overactive Bladder" ], "interventions": [ { "name": "conjugated estrogen", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Loyola University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "55 Years", "maximum_age": null, "sex": "FEMALE", "summary": "55 Years and older · Female only" }, "enrollment_count": 27, "start_date": "2015-12", "completion_date": "2017-06", "has_results": true, "last_update_posted_date": "2021-04-15", "last_synced_at": "2026-09-17T01:49:09.725Z", "location_count": 1, "location_summary": "Maywood, Illinois", "locations": [ { "city": "Maywood", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02524769" }, { "nct_id": "NCT02195986", "title": "A Comparison of Estradiol Vaginal Cream to Estrace® Cream in 350 Postmenopausal Females With Atrophic Vaginitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Atrophic Vaginitis" ], "interventions": [ { "name": "Estradiol Vaginal Cream, 0.01%", "type": "DRUG" }, { "name": "Estrace® 0.01% cream", "type": "DRUG" }, { "name": "Placebo Vaginal Cream", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mylan Pharmaceuticals Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "40 Years", "maximum_age": "70 Years", "sex": "FEMALE", "summary": "40 Years to 70 Years · Female only" }, "enrollment_count": 366, "start_date": "2014-06", "completion_date": "2014-12", "has_results": true, "last_update_posted_date": "2022-03-09", "last_synced_at": "2026-09-17T01:49:09.725Z", "location_count": 21, "location_summary": "Tucson, Arizona • Los Angeles, California • Sacramento, California + 16 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02195986" }, { "nct_id": "NCT03332303", "title": "Study to Evaluate the Equivalence of Estradiol Vaginal Cream to Reference Standard in the Treatment of Vaginal Atrophy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Vulvar and Vaginal Atrophy" ], "interventions": [ { "name": "Estrace® Cream", "type": "DRUG" }, { "name": "Estradiol Vaginal Cream", "type": "DRUG" }, { "name": "Vehicle Cream", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Prasco LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": "75 Years", "sex": "FEMALE", "summary": "30 Years to 75 Years · Female only" }, "enrollment_count": 540, "start_date": "2017-10-26", "completion_date": "2018-03-15", "has_results": true, "last_update_posted_date": "2024-05-30", "last_synced_at": "2026-09-17T01:49:09.725Z", "location_count": 27, "location_summary": "Sacramento, California • San Diego, California • Denver, Colorado + 23 more", "locations": [ { "city": "Sacramento", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "DeLand", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03332303" }, { "nct_id": "NCT03294538", "title": "Study to Evaluate Equivalence of Estradiol Vaginal Cream 0.01% to Estrace® Cream 0.01% in Atrophic Vaginitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Atrophic Vaginitis" ], "interventions": [ { "name": "Generic Estradiol Vaginal Cream USP, 0.01%", "type": "DRUG" }, { "name": "Estrace® Vaginal Cream USP, 0.01%", "type": "DRUG" }, { "name": "Vehicle Vaginal Cream", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Actavis Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": "75 Years", "sex": "FEMALE", "summary": "30 Years to 75 Years · Female only" }, "enrollment_count": 663, "start_date": "2016-05-18", "completion_date": "2017-02-15", "has_results": true, "last_update_posted_date": "2019-12-26", "last_synced_at": "2026-09-17T01:49:09.725Z", "location_count": 44, "location_summary": "Tucson, Arizona • La Mesa, California • Sacramento, California + 33 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "La Mesa", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03294538" } ] }