{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Estradiol+100+Micrograms+Patch", "query": { "intervention": "Estradiol 100 Micrograms Patch" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 16, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Estradiol+100+Micrograms+Patch&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-20T09:44:13.803Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01301183", "title": "Effects of Anorexia Nervosa on Peak Bone Mass", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Anorexia Nervosa" ], "interventions": [ { "name": "RhIGF-1 with transdermal 17-beta estradiol", "type": "DRUG" }, { "name": "Placebo and transdermal 17-beta estradiol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "14 Years", "maximum_age": "22 Years", "sex": "FEMALE", "summary": "14 Years to 22 Years · Female only" }, "enrollment_count": 75, "start_date": "2011-02", "completion_date": "2020-03", "has_results": true, "last_update_posted_date": "2021-07-13", "last_synced_at": "2026-09-20T09:44:13.803Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01301183" }, { "nct_id": "NCT00088153", "title": "Effects of Anorexia Nervosa on Bone Mass in Adolescents", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Anorexia Nervosa" ], "interventions": [ { "name": "Physiologic Estrogen/progesterone", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "12 Years", "maximum_age": "18 Years", "sex": "FEMALE", "summary": "12 Years to 18 Years · Female only" }, "enrollment_count": 110, "start_date": "2003-07", "completion_date": "2011-06", "has_results": true, "last_update_posted_date": "2021-11-02", "last_synced_at": "2026-09-20T09:44:13.803Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00088153" }, { "nct_id": "NCT00030147", "title": "Raloxifene and Rimostil for Perimenopause-Related Depression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Perimenopausal Depression", "Depression" ], "interventions": [ { "name": "Raloxifene", "type": "DRUG" }, { "name": "Rimostil", "type": "DRUG" }, { "name": "Transdermal Estradiol", "type": "DRUG" }, { "name": "Placebo skin patch and placebo tablets", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Mental Health (NIMH)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "60 Years", "sex": "FEMALE", "summary": "40 Years to 60 Years · Female only" }, "enrollment_count": 65, "start_date": "2002-02", "completion_date": "2015-06", "has_results": true, "last_update_posted_date": "2016-09-05", "last_synced_at": "2026-09-20T09:44:13.803Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00030147" }, { "nct_id": "NCT00059228", "title": "Clinical Trial of Estrogen for Postpartum Depression", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Postpartum Depression", "Depression" ], "interventions": [ { "name": "17beta Estradiol", "type": "DRUG" }, { "name": "Placebos", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Mental Health (NIMH)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "20 Years", "maximum_age": "45 Years", "sex": "FEMALE", "summary": "20 Years to 45 Years · Female only" }, "enrollment_count": 12, "start_date": "2003-04-17", "completion_date": "2016-11-15", "has_results": true, "last_update_posted_date": "2018-06-13", "last_synced_at": "2026-09-20T09:44:13.803Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00059228" }, { "nct_id": "NCT00946192", "title": "Fat Mediated Modulation of Reproductive and Endocrine Function in Young Athletes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Exercise-related Amenorrhea" ], "interventions": [ { "name": "Transdermal 17Beta-estradiol, progesterone", "type": "DRUG" }, { "name": "Ethinyl Estradiol + Desogestrel", "type": "DRUG" }, { "name": "Sham Comparator", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DRUG", "DIETARY_SUPPLEMENT" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "14 Years", "maximum_age": "21 Years", "sex": "FEMALE", "summary": "14 Years to 21 Years · Female only" }, "enrollment_count": 121, "start_date": "2009-05", "completion_date": "2021-04", "has_results": true, "last_update_posted_date": "2021-06-11", "last_synced_at": "2026-09-20T09:44:13.803Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00946192" }, { "nct_id": "NCT02922348", "title": "Hormone Replacement for Premature Ovarian Insufficiency", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Primary Ovarian Insufficiency" ], "interventions": [ { "name": "Hormone Replacement Therapy", "type": "DRUG" }, { "name": "Combined Oral Contraceptives", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "14 Years", "maximum_age": "45 Years", "sex": "FEMALE", "summary": "14 Years to 45 Years · Female only" }, "enrollment_count": 0, "start_date": "2016-03-01", "completion_date": "2018-12-01", "has_results": false, "last_update_posted_date": "2019-07-05", "last_synced_at": "2026-09-20T09:44:13.803Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02922348" }, { "nct_id": "NCT00066157", "title": "Alzheimer's Disease: Therapeutic Potential of Estrogen", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Alzheimer Disease" ], "interventions": [ { "name": "Transdermal estradiol", "type": "DRUG" }, { "name": "Medroxyprogesterone", "type": "DRUG" }, { "name": "Placebo Patch", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Wisconsin, Madison", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "55 Years", "maximum_age": "90 Years", "sex": "FEMALE", "summary": "55 Years to 90 Years · Female only" }, "enrollment_count": 42, "start_date": "2001-09", "completion_date": "2007-12", "has_results": false, "last_update_posted_date": "2018-08-23", "last_synced_at": "2026-09-20T09:44:13.803Z", "location_count": 1, "location_summary": "Madison, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT00066157" }, { "nct_id": "NCT04833140", "title": "Estrogen Administration for the Treatment of NASH in Postmenopausal Women", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "NASH - Nonalcoholic Steatohepatitis" ], "interventions": [ { "name": "Estradiol patch", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "45 Years", "maximum_age": "70 Years", "sex": "FEMALE", "summary": "45 Years to 70 Years · Female only" }, "enrollment_count": 50, "start_date": "2021-12-02", "completion_date": "2027-07-09", "has_results": false, "last_update_posted_date": "2026-08-07", "last_synced_at": "2026-09-20T09:44:13.803Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04833140" }, { "nct_id": "NCT00827151", "title": "Bone Mass Accrual in Adolescent Athletes", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Amenorrhea", "Bone Loss" ], "interventions": [ { "name": "Estrogen", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "21 Years", "sex": "FEMALE", "summary": "18 Years to 21 Years · Female only" }, "enrollment_count": 0, "start_date": "2008-12", "completion_date": "2015-01", "has_results": false, "last_update_posted_date": "2021-10-26", "last_synced_at": "2026-09-20T09:44:13.803Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00827151" }, { "nct_id": "NCT06851754", "title": "Hormone Replacement Therapy in Adolescents With Premature Ovarian Insufficiency", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Premature Ovarian Insufficiency" ], "interventions": [ { "name": "Progesterone", "type": "DRUG" }, { "name": "Estrogen Patch", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "11 Years", "maximum_age": "19 Years", "sex": "FEMALE", "summary": "11 Years to 19 Years · Female only" }, "enrollment_count": 185, "start_date": "2025-07-17", "completion_date": "2031-12-31", "has_results": false, "last_update_posted_date": "2026-09-18", "last_synced_at": "2026-09-20T09:44:13.803Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT06851754" } ] }