{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Exercise+-+High-intensity+exercise&page=13",
    "query": {
      "intervention": "Exercise - High-intensity exercise",
      "page": 13
    },
    "page_size": 10
  },
  "pagination": {
    "page": 13,
    "page_size": 10,
    "total_count": 515,
    "total_pages": 52,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Exercise+-+High-intensity+exercise&page=14&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Exercise+-+High-intensity+exercise&page=12&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-04T00:48:19.003Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03476785",
      "title": "Prevention of Cardiovascular Stiffening With Aging and Hypertensive Heart Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lv Hypertrophy",
        "Heart Failure, Diastolic",
        "Stiffness, Vascular"
      ],
      "interventions": [
        {
          "name": "High intensity exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Yoga",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "40 Years to 64 Years"
      },
      "enrollment_count": 56,
      "start_date": "2015-06-01",
      "completion_date": "2019-07-02",
      "has_results": false,
      "last_update_posted_date": "2019-10-14",
      "last_synced_at": "2026-11-04T00:48:19.003Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03476785"
    },
    {
      "nct_id": "NCT06886789",
      "title": "SMART to Optimize an Intervention to Maintain Health Improvements After Cardiac Rehabilitation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Diseases",
        "Cardiac Rehabilitation"
      ],
      "interventions": [
        {
          "name": "Text Messaging",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Fully Automated Online Program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Low-Intensity Cardiac Rehabilitation Maintenance Program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "High Intensity Cardiac Rehabilitation Maintenance Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The Miriam Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2026-04-01",
      "completion_date": "2030-08",
      "has_results": false,
      "last_update_posted_date": "2026-04-28",
      "last_synced_at": "2026-11-04T00:48:19.003Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06886789"
    },
    {
      "nct_id": "NCT07058974",
      "title": "A Study of Exercise and Pharmacologic Intervention on Systemic Inflammation",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Smokers",
        "Former Smokers"
      ],
      "interventions": [
        {
          "name": "lamivudine",
          "type": "DRUG"
        },
        {
          "name": "rapamycin",
          "type": "DRUG"
        },
        {
          "name": "Exercise Regimen",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Spermidine",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "60 Years to 85 Years"
      },
      "enrollment_count": 20,
      "start_date": "2025-08-12",
      "completion_date": "2027-06-15",
      "has_results": false,
      "last_update_posted_date": "2026-08-27",
      "last_synced_at": "2026-11-04T00:48:19.003Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07058974"
    },
    {
      "nct_id": "NCT07792603",
      "title": "Daily Upgrade Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Women"
      ],
      "interventions": [
        {
          "name": "Essential Amino Acid+",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Non-Calorie Placebo",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "High intensity Interval Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "No Exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "25 Years to 45 Years · Female only"
      },
      "enrollment_count": 44,
      "start_date": "2026-08-31",
      "completion_date": "2027-04",
      "has_results": false,
      "last_update_posted_date": "2026-09-03",
      "last_synced_at": "2026-11-04T00:48:19.003Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07792603"
    },
    {
      "nct_id": "NCT01848353",
      "title": "Financial Incentives to Exercise for Adolescents",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insulin Resistance",
        "Obesity",
        "Sedentary Lifestyle"
      ],
      "interventions": [
        {
          "name": "Exercise training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "20 Years",
        "sex": "ALL",
        "summary": "11 Years to 20 Years"
      },
      "enrollment_count": 142,
      "start_date": "2013-05",
      "completion_date": "2017-05",
      "has_results": true,
      "last_update_posted_date": "2019-04-03",
      "last_synced_at": "2026-11-04T00:48:19.003Z",
      "location_count": 2,
      "location_summary": "Hugo, Oklahoma • Talihina, Oklahoma",
      "locations": [
        {
          "city": "Hugo",
          "state": "Oklahoma"
        },
        {
          "city": "Talihina",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01848353"
    },
    {
      "nct_id": "NCT05926024",
      "title": "Long-Term Follow-Up in Women With Early Breast Cancer Three Years of More Post Primary Treatment",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Exercise Recall Patient Reported Outcomes",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health Behavior Questionnaire (HBQ)30 Patient Reported Outcomes",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Functional Assessment of Cancer Therapy-General (FACT-G) Patient Reported Outcomes",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) Patient Reported Outcomes",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes PROMIS Cognitive Function (Short Form 8a)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes Functional Assessment of Cancer-Gynecology Oncology Group-Neurotoxicity (FACT/GOG-NTX-12)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes PROMIS",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes FACT-Endocrine Symptoms",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes Penn Arthralgia Aging Survey",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes PRO-CTCAE (patient-reported CTCAE)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "p16 tumor suppressor gene",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "UNC Lineberger Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "21 Years and older · Female only"
      },
      "enrollment_count": 253,
      "start_date": "2023-01-06",
      "completion_date": "2028-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-11",
      "last_synced_at": "2026-11-04T00:48:19.003Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05926024"
    },
    {
      "nct_id": "NCT04086615",
      "title": "Trial of Neurostimulation and Blood Flow Restriction for PFPS in Active Duty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patellofemoral Pain Syndrome"
      ],
      "interventions": [
        {
          "name": "NMES and exercise supplemented with high BFR",
          "type": "DEVICE"
        },
        {
          "name": "NMES and exercise supplemented with low BFR",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Tennessee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "44 Years",
        "sex": "ALL",
        "summary": "18 Years to 44 Years"
      },
      "enrollment_count": 84,
      "start_date": "2020-08-04",
      "completion_date": "2022-03-31",
      "has_results": false,
      "last_update_posted_date": "2022-06-06",
      "last_synced_at": "2026-11-04T00:48:19.003Z",
      "location_count": 1,
      "location_summary": "Fort Campbell North, Kentucky",
      "locations": [
        {
          "city": "Fort Campbell North",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04086615"
    },
    {
      "nct_id": "NCT03225898",
      "title": "Upper- and Lower-body Resistance Exercise With and Without Blood Flow Restriction on Hemodynamics and Vascular Function",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Endothelial Dysfunction",
        "Autonomic Dysfunction"
      ],
      "interventions": [
        {
          "name": "Resistance Exercise with Blood Flow Restriction",
          "type": "OTHER"
        },
        {
          "name": "High-intensity Resistance Exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Kent State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 20,
      "start_date": "2017-06-14",
      "completion_date": "2018-06-13",
      "has_results": false,
      "last_update_posted_date": "2017-07-24",
      "last_synced_at": "2026-11-04T00:48:19.003Z",
      "location_count": 1,
      "location_summary": "Kent, Ohio",
      "locations": [
        {
          "city": "Kent",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03225898"
    },
    {
      "nct_id": "NCT01775163",
      "title": "Effect of Exercise-Induced Weight Loss on Energy Metabolism",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Metabolism",
        "Weight Loss"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Pennington Biomedical Research Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 54,
      "start_date": "2010-12",
      "completion_date": "2015-02",
      "has_results": false,
      "last_update_posted_date": "2021-08-24",
      "last_synced_at": "2026-11-04T00:48:19.003Z",
      "location_count": 1,
      "location_summary": "Baton Rouge, Louisiana",
      "locations": [
        {
          "city": "Baton Rouge",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01775163"
    },
    {
      "nct_id": "NCT02665052",
      "title": "Translating Intensive Arm Rehabilitation in Stroke to a Telerehabilitation Format",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke",
        "Hemiparesis"
      ],
      "interventions": [
        {
          "name": "Home-Based BATRAC plus TTT",
          "type": "DEVICE"
        },
        {
          "name": "Lab-based BATRAC plus TTT",
          "type": "DEVICE"
        },
        {
          "name": "Delayed Entry Usual Care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 63,
      "start_date": "2017-05-01",
      "completion_date": "2020-01-16",
      "has_results": true,
      "last_update_posted_date": "2021-03-17",
      "last_synced_at": "2026-11-04T00:48:19.003Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02665052"
    }
  ]
}