{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Exercise+-+High-intensity+exercise&page=22",
    "query": {
      "intervention": "Exercise - High-intensity exercise",
      "page": 22
    },
    "page_size": 10
  },
  "pagination": {
    "page": 22,
    "page_size": 10,
    "total_count": 516,
    "total_pages": 52,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Exercise+-+High-intensity+exercise&page=23&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Exercise+-+High-intensity+exercise&page=21&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-06T03:38:51.059Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00962962",
      "title": "Exercise Dose-Response Effects in Prediabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pre-Diabetes"
      ],
      "interventions": [
        {
          "name": "Aerobic Exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exercise and Diet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "45 Years to 75 Years"
      },
      "enrollment_count": 288,
      "start_date": "2009-07",
      "completion_date": "2013-08",
      "has_results": false,
      "last_update_posted_date": "2014-07-15",
      "last_synced_at": "2026-11-06T03:38:51.059Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00962962"
    },
    {
      "nct_id": "NCT03225898",
      "title": "Upper- and Lower-body Resistance Exercise With and Without Blood Flow Restriction on Hemodynamics and Vascular Function",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Endothelial Dysfunction",
        "Autonomic Dysfunction"
      ],
      "interventions": [
        {
          "name": "Resistance Exercise with Blood Flow Restriction",
          "type": "OTHER"
        },
        {
          "name": "High-intensity Resistance Exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Kent State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 20,
      "start_date": "2017-06-14",
      "completion_date": "2018-06-13",
      "has_results": false,
      "last_update_posted_date": "2017-07-24",
      "last_synced_at": "2026-11-06T03:38:51.059Z",
      "location_count": 1,
      "location_summary": "Kent, Ohio",
      "locations": [
        {
          "city": "Kent",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03225898"
    },
    {
      "nct_id": "NCT03657628",
      "title": "Physical Activity, Proliferation and Immune Markers in Benign Breast Tissue",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Exercise Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Dana-Farber Cancer Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 60,
      "start_date": "2018-09-17",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-10-26",
      "last_synced_at": "2026-11-06T03:38:51.059Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03657628"
    },
    {
      "nct_id": "NCT05295719",
      "title": "Combining HIIT and n-3 PUFA to Reduce Inflammation and Improve Metabolic Health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Inflammation",
        "Human Microbiome",
        "Insulin Resistance",
        "Dyslipidemias"
      ],
      "interventions": [
        {
          "name": "Omega-3 polyunsaturated fatty acid",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "High-Intensity Interval Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Safflower oil",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Low-intensity training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "BEHAVIORAL"
      ],
      "sponsor": "Texas Tech University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 129,
      "start_date": "2022-09-01",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-09-11",
      "last_synced_at": "2026-11-06T03:38:51.059Z",
      "location_count": 1,
      "location_summary": "Lubbock, Texas",
      "locations": [
        {
          "city": "Lubbock",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05295719"
    },
    {
      "nct_id": "NCT05291767",
      "title": "High Fat Meal and Postprandial TG Levels With and Without Exercise Intervention",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ketogenic Diet",
        "Exercise"
      ],
      "interventions": [
        {
          "name": "Diet",
          "type": "OTHER"
        },
        {
          "name": "Exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 7,
      "start_date": "2022-03-28",
      "completion_date": "2022-11-01",
      "has_results": false,
      "last_update_posted_date": "2023-01-31",
      "last_synced_at": "2026-11-06T03:38:51.059Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05291767"
    },
    {
      "nct_id": "NCT04733287",
      "title": "Heat Therapy and Muscle Function Study",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Exercise Intolerance",
        "Aging",
        "Heat Therapy",
        "High Intensity Interval Training"
      ],
      "interventions": [
        {
          "name": "High Intensity Interval Training of the Knee Extensors",
          "type": "OTHER"
        },
        {
          "name": "Muscle Heat Therapy",
          "type": "OTHER"
        },
        {
          "name": "Muscle Disuse",
          "type": "OTHER"
        },
        {
          "name": "Sham Heat Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham Young University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "18 Years to 95 Years"
      },
      "enrollment_count": 148,
      "start_date": "2021-04-01",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2021-02-02",
      "last_synced_at": "2026-11-06T03:38:51.059Z",
      "location_count": 1,
      "location_summary": "Provo, Utah",
      "locations": [
        {
          "city": "Provo",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04733287"
    },
    {
      "nct_id": "NCT03545867",
      "title": "Energetic Response to Feeding and Exercise in SCI",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries"
      ],
      "interventions": [
        {
          "name": "Seated control (CON)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Moderate intensity continuous (MICT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "High intensity interval training (HIIT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Circuit resistance training (CRT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Liquid Meal",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2018-02-28",
      "completion_date": "2018-09-30",
      "has_results": false,
      "last_update_posted_date": "2020-06-19",
      "last_synced_at": "2026-11-06T03:38:51.059Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03545867"
    },
    {
      "nct_id": "NCT05571384",
      "title": "High Intensity Body-weight Circuit Training Feasibility and Efficacy for in Middle Aged Persons With Type 2 Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type2diabetes"
      ],
      "interventions": [
        {
          "name": "high intensity body-weight circuit",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Kennesaw State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "40 Years to 65 Years"
      },
      "enrollment_count": 22,
      "start_date": "2022-07-26",
      "completion_date": "2025-07-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-05",
      "last_synced_at": "2026-11-06T03:38:51.059Z",
      "location_count": 1,
      "location_summary": "Kennesaw, Georgia",
      "locations": [
        {
          "city": "Kennesaw",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05571384"
    },
    {
      "nct_id": "NCT00662103",
      "title": "Aerobic Exercise, Resistance Exercise, or Flexibility and Relaxation Training in Inactive Older Female Breast Cancer Survivors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer",
        "Cancer Survivor",
        "Fatigue",
        "Long-term Effects Secondary to Cancer Therapy in Adults",
        "Psychosocial Effects of Cancer and Its Treatment"
      ],
      "interventions": [
        {
          "name": "exercise intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "laboratory biomarker analysis",
          "type": "OTHER"
        },
        {
          "name": "questionnaire administration",
          "type": "OTHER"
        },
        {
          "name": "survey administration",
          "type": "OTHER"
        },
        {
          "name": "assessment of therapy complications",
          "type": "PROCEDURE"
        },
        {
          "name": "fatigue assessment and management",
          "type": "PROCEDURE"
        },
        {
          "name": "management of therapy complications",
          "type": "PROCEDURE"
        },
        {
          "name": "psychosocial assessment and care",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "OHSU Knight Cancer Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "120 Years",
        "sex": "FEMALE",
        "summary": "65 Years to 120 Years · Female only"
      },
      "enrollment_count": 115,
      "start_date": "2008-03",
      "completion_date": "2010-06",
      "has_results": false,
      "last_update_posted_date": "2015-10-15",
      "last_synced_at": "2026-11-06T03:38:51.059Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00662103"
    },
    {
      "nct_id": "NCT05551325",
      "title": "Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critical Illness",
        "Sleep Deprivation",
        "Circadian Rhythm Sleep Disorder, Unspecified"
      ],
      "interventions": [
        {
          "name": "Chronobundle - light",
          "type": "OTHER"
        },
        {
          "name": "chronobundle - feeding",
          "type": "OTHER"
        },
        {
          "name": "chronobundle - mobility",
          "type": "OTHER"
        },
        {
          "name": "chronobundle - sleep",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2024-05-13",
      "completion_date": "2029-06-29",
      "has_results": false,
      "last_update_posted_date": "2026-05-20",
      "last_synced_at": "2026-11-06T03:38:51.059Z",
      "location_count": 2,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05551325"
    }
  ]
}