{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Experimental+Dentifrice&page=2",
    "query": {
      "intervention": "Experimental Dentifrice",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Experimental+Dentifrice&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-30T02:35:54.620Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03267511",
      "title": "A Study to Investigate the Stain and Plaque Removal Capability of Two Experimental Potassium Nitrate Dentifrices",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Oral Hygiene"
      ],
      "interventions": [
        {
          "name": "5% KNO3 / 0.2542% NaF dentifrice with 0.5% spherical silica",
          "type": "DRUG"
        },
        {
          "name": "5% KNO3 / 0.2542% NaF dentifrice with 1% spherical silica and 5% STP",
          "type": "DRUG"
        },
        {
          "name": "5% KNO3 / 0.2542% NaF dentifrice with 6% abrasive silica",
          "type": "DRUG"
        },
        {
          "name": "5% KNO3 / 0.2543% NaF dentifrice with 16% abrasive silica and 5% STP",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 123,
      "start_date": "2017-09-25",
      "completion_date": "2017-12-02",
      "has_results": true,
      "last_update_posted_date": "2019-01-08",
      "last_synced_at": "2026-09-30T02:35:54.620Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03267511"
    },
    {
      "nct_id": "NCT02151058",
      "title": "A Clinical Trial to Test the Effect of a Marketed Mouth Rinse on Stain Removal",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tooth Stain"
      ],
      "interventions": [
        {
          "name": "Colgate® Regular Cavity Protection",
          "type": "DRUG"
        },
        {
          "name": "Experimental Mouth Rinse",
          "type": "DRUG"
        },
        {
          "name": "Crest® 3D White Multi-Care Whitening Rinse, Glamorous White, Fresh Mint",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Johnson & Johnson Consumer and Personal Products Worldwide",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 227,
      "start_date": "2014-06",
      "completion_date": "2014-07",
      "has_results": true,
      "last_update_posted_date": "2015-06-01",
      "last_synced_at": "2026-09-30T02:35:54.620Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02151058"
    },
    {
      "nct_id": "NCT04155658",
      "title": "Evaluation of Efficacy of Sodium Monofluorophosphate (SMPF) Toothpastes on Enamel Lesion Remineralisation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Enamel Caries"
      ],
      "interventions": [
        {
          "name": "Experimental Toothpaste containing 1450ppm SMFP",
          "type": "OTHER"
        },
        {
          "name": "Toothpaste containing 1450ppm SMFP",
          "type": "OTHER"
        },
        {
          "name": "Toothpaste with no fluoride",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Unilever R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 55,
      "start_date": "2019-11-25",
      "completion_date": "2020-04-30",
      "has_results": false,
      "last_update_posted_date": "2020-05-18",
      "last_synced_at": "2026-09-30T02:35:54.620Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04155658"
    },
    {
      "nct_id": "NCT02207400",
      "title": "To Evaluate Efficacy and Tolerability of Sodium Bicarbonate Toothpaste and Its Effect on Opportunistic or Resistant Organisms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Oral Hygiene"
      ],
      "interventions": [
        {
          "name": "Sodium bicarbonate and sodium fluoride",
          "type": "DRUG"
        },
        {
          "name": "Sodium fluoride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 246,
      "start_date": "2014-08-25",
      "completion_date": "2015-04-30",
      "has_results": true,
      "last_update_posted_date": "2018-07-31",
      "last_synced_at": "2026-09-30T02:35:54.620Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02207400"
    },
    {
      "nct_id": "NCT07501455",
      "title": "Comparison of the Effects of Oral Hygiene Regimens on Clinical, Immunomodulatory, and Microbial Outcomes and Oral Tolerance in People With Gingivitis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Microbiome",
        "Cytokines",
        "Plaque",
        "Gingivitis",
        "Gingival Bleeding"
      ],
      "interventions": [
        {
          "name": "Distilled Water",
          "type": "OTHER"
        },
        {
          "name": "Marketed Comparator 1",
          "type": "OTHER"
        },
        {
          "name": "Marketed Comparator 2",
          "type": "OTHER"
        },
        {
          "name": "Prototype Rinse 1",
          "type": "OTHER"
        },
        {
          "name": "Prototype Rinse 2",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Kenvue Brands LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 250,
      "start_date": "2026-02-26",
      "completion_date": "2026-05-05",
      "has_results": false,
      "last_update_posted_date": "2026-03-30",
      "last_synced_at": "2026-09-30T02:35:54.620Z",
      "location_count": 1,
      "location_summary": "Somerville, Massachusetts",
      "locations": [
        {
          "city": "Somerville",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07501455"
    },
    {
      "nct_id": "NCT07428603",
      "title": "Extrinsic Tooth Whitening Evaluation of a Whitening Toothpaste",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stain Removal Efficacy"
      ],
      "interventions": [
        {
          "name": "Whitening Test Dentifrice (Code 826)",
          "type": "OTHER"
        },
        {
          "name": "Control dentifrice (Code 378)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Church & Dwight Company, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 118,
      "start_date": "2024-08-08",
      "completion_date": "2024-09-20",
      "has_results": false,
      "last_update_posted_date": "2026-02-24",
      "last_synced_at": "2026-09-30T02:35:54.620Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07428603"
    },
    {
      "nct_id": "NCT01727258",
      "title": "A Test on a New Experimental Mouth Rinse for Relieving Tooth Sensitivity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dentin Sensitivity"
      ],
      "interventions": [
        {
          "name": "Mouth Rinse",
          "type": "DEVICE"
        },
        {
          "name": "Fluoride Toothpaste",
          "type": "DRUG"
        },
        {
          "name": "Potassium Nitrate Toothpaste",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Johnson & Johnson Consumer and Personal Products Worldwide",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 153,
      "start_date": "2012-12",
      "completion_date": "2013-02",
      "has_results": true,
      "last_update_posted_date": "2015-06-10",
      "last_synced_at": "2026-09-30T02:35:54.620Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01727258"
    },
    {
      "nct_id": "NCT02753075",
      "title": "A Study in Dentinal Hypersensitivity (DH) Participants to Assess the Efficacy of an Occluding Dentifrice.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dentin Sensitivity"
      ],
      "interventions": [
        {
          "name": "Experimental Oral Rinse 1",
          "type": "DEVICE"
        },
        {
          "name": "Experimental Oral Rinse 2",
          "type": "DEVICE"
        },
        {
          "name": "Placebo Oral Rinse",
          "type": "OTHER"
        },
        {
          "name": "Fluoride toothpaste",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER",
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 240,
      "start_date": "2015-09-08",
      "completion_date": "2015-12-18",
      "has_results": true,
      "last_update_posted_date": "2018-08-27",
      "last_synced_at": "2026-09-30T02:35:54.620Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02753075"
    },
    {
      "nct_id": "NCT07255040",
      "title": "A Clinical Study to Evaluate the Effectiveness of an Experimental Toothpaste in Improving Gum Health and Reducing Plaque Accumulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Plaque",
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Test Dentifrice",
          "type": "DRUG"
        },
        {
          "name": "Parodontax Complete Protection",
          "type": "DRUG"
        },
        {
          "name": "Colgate Cavity Protection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "HALEON",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 284,
      "start_date": "2025-11-19",
      "completion_date": "2026-07-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-05",
      "last_synced_at": "2026-09-30T02:35:54.620Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07255040"
    },
    {
      "nct_id": "NCT04123665",
      "title": "A Phase 3 Clinical Study Investigating the Gingivitis Efficacy of a Test Dentifrice Containing Stannous Fluoride",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Stannous fluoride",
          "type": "DRUG"
        },
        {
          "name": "Sodium monofluorophosphate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 98,
      "start_date": "2013-05-28",
      "completion_date": "2013-12-11",
      "has_results": true,
      "last_update_posted_date": "2020-01-31",
      "last_synced_at": "2026-09-30T02:35:54.620Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04123665"
    }
  ]
}