{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Extended-release+Buprenorphine&page=2",
    "query": {
      "intervention": "Extended-release Buprenorphine",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Extended-release+Buprenorphine&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-27T15:21:41.514Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03015246",
      "title": "Effects of Buprenorphine/Naloxone Dose on Experimental Stress Reactivity and Opioid Abstinence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Heroin Dependence",
        "Opioid Use Disorder"
      ],
      "interventions": [
        {
          "name": "Extended release morphine",
          "type": "DRUG"
        },
        {
          "name": "Buprenorphine/Naloxone low dose",
          "type": "DRUG"
        },
        {
          "name": "Buprenorphine/Naloxone moderate dose",
          "type": "DRUG"
        },
        {
          "name": "Buprenorphine/Naloxone high dose",
          "type": "DRUG"
        },
        {
          "name": "Active stressor",
          "type": "DRUG"
        },
        {
          "name": "Placebo stressor",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wayne State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 26,
      "start_date": "2016-12",
      "completion_date": "2020-08",
      "has_results": false,
      "last_update_posted_date": "2020-11-10",
      "last_synced_at": "2026-09-27T15:21:41.514Z",
      "location_count": 1,
      "location_summary": "Overland Park, Kansas",
      "locations": [
        {
          "city": "Overland Park",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03015246"
    },
    {
      "nct_id": "NCT05704543",
      "title": "Evaluation of Buprenorphine Extended-Release Subcutaneous Injection at Alternative Injection Locations",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Opioid Use Disorder"
      ],
      "interventions": [
        {
          "name": "Buprenorphine Extended-Release Injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Indivior Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 132,
      "start_date": "2023-03-01",
      "completion_date": "2023-11-01",
      "has_results": true,
      "last_update_posted_date": "2025-01-07",
      "last_synced_at": "2026-09-27T15:21:41.514Z",
      "location_count": 6,
      "location_summary": "San Diego, California • Hollywood, Florida • Miami Lakes, Florida + 3 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "Miami Lakes",
          "state": "Florida"
        },
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        },
        {
          "city": "DeSoto",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05704543"
    },
    {
      "nct_id": "NCT05262270",
      "title": "Extended-Release Naltrexone and Monthly Extended-Release Buprenorphine for Cocaine Use Disorder (CURB-2)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cocaine Use Disorder"
      ],
      "interventions": [
        {
          "name": "Extended-Release Naltrexone",
          "type": "DRUG"
        },
        {
          "name": "Extended Release Buprenorphine",
          "type": "DRUG"
        },
        {
          "name": "Placebo (PLB) Injectable matched to XR-NTX",
          "type": "DRUG"
        },
        {
          "name": "Placebo (PLB) Injectable matched to XR-BUP",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 427,
      "start_date": "2023-04-18",
      "completion_date": "2025-07-21",
      "has_results": false,
      "last_update_posted_date": "2025-10-21",
      "last_synced_at": "2026-09-27T15:21:41.514Z",
      "location_count": 12,
      "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 8 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05262270"
    },
    {
      "nct_id": "NCT03911466",
      "title": "Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Opioid-Related Disorders",
        "Drug Addiction",
        "Pregnancy Related",
        "Substance Abuse",
        "Drug Abuse",
        "Neonatal Abstinence Syndrome",
        "Neonatal Opioid Withdrawal Syndrome",
        "Drug Abuse in Pregnancy"
      ],
      "interventions": [
        {
          "name": "Buprenorphine Injection",
          "type": "DRUG"
        },
        {
          "name": "Buprenorphine Sublingual Product",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "T. John Winhusen, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "41 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 41 Years · Female only"
      },
      "enrollment_count": 97,
      "start_date": "2020-07-21",
      "completion_date": "2024-11-06",
      "has_results": false,
      "last_update_posted_date": "2026-03-16",
      "last_synced_at": "2026-09-27T15:21:41.514Z",
      "location_count": 12,
      "location_summary": "Jacksonville, Florida • Boston, Massachusetts • Albuquerque, New Mexico + 8 more",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03911466"
    },
    {
      "nct_id": "NCT04309565",
      "title": "Transitions Clinic Network: Post Incarceration Addiction Treatment, Healthcare, and Social Support",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Addiction"
      ],
      "interventions": [
        {
          "name": "Transitions Clinic Network Primary Care",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Primary Care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 398,
      "start_date": "2021-04-21",
      "completion_date": "2025-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-12",
      "last_synced_at": "2026-09-27T15:21:41.514Z",
      "location_count": 4,
      "location_summary": "New Haven, Connecticut • Minneapolis, Minnesota • The Bronx, New York + 1 more",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04309565"
    },
    {
      "nct_id": "NCT07485335",
      "title": "A Bundled Intervention to End Opioid Overdoses",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Opioid Use Disorder",
        "Opioid Overdose"
      ],
      "interventions": [
        {
          "name": "Bundled intervention (Experimental)",
          "type": "OTHER"
        },
        {
          "name": "control group",
          "type": "OTHER"
        },
        {
          "name": "Buprenorphine (Experimental)",
          "type": "DRUG"
        },
        {
          "name": "Scheduled Peer Support Specialist (Experimental)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Telemedicine Buprenorphine Treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2026-09-07",
      "completion_date": "2030-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-18",
      "last_synced_at": "2026-09-27T15:21:41.514Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07485335"
    },
    {
      "nct_id": "NCT04454411",
      "title": "Brain Mechanisms of Pharmacotherapy in Opioid Use Disorder",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Opioid Dependence"
      ],
      "interventions": [
        {
          "name": "Brixadi",
          "type": "DRUG"
        },
        {
          "name": "Vivitrol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 3,
      "start_date": "2022-08-01",
      "completion_date": "2024-08-31",
      "has_results": true,
      "last_update_posted_date": "2025-08-06",
      "last_synced_at": "2026-09-27T15:21:41.514Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04454411"
    },
    {
      "nct_id": "NCT01871285",
      "title": "Evaluation of the Tolerability of Switching Subjects on Chronic ATC Opioid Therapy to Buprenorphine HCl Buccal Film",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Buprenorphine",
          "type": "DRUG"
        },
        {
          "name": "Placebo film",
          "type": "DRUG"
        },
        {
          "name": "Oxycodone",
          "type": "DRUG"
        },
        {
          "name": "Morphine sulfate",
          "type": "DRUG"
        },
        {
          "name": "Placebo capsule",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "BioDelivery Sciences International",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 39,
      "start_date": "2013-06",
      "completion_date": "2014-07",
      "has_results": true,
      "last_update_posted_date": "2017-02-27",
      "last_synced_at": "2026-09-27T15:21:41.514Z",
      "location_count": 3,
      "location_summary": "Overland Park, Kansas • Philadelphia, Pennsylvania • Salt Lake City, Utah",
      "locations": [
        {
          "city": "Overland Park",
          "state": "Kansas"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01871285"
    },
    {
      "nct_id": "NCT01999946",
      "title": "Extended-Release Naltrexone Opioid Treatment at Jail Re-Entry",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Heroin Dependence",
        "Opioid-Related Disorders"
      ],
      "interventions": [
        {
          "name": "Extended-Release Naltrexone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 217,
      "start_date": "2014-06-27",
      "completion_date": "2020-12-24",
      "has_results": true,
      "last_update_posted_date": "2021-06-25",
      "last_synced_at": "2026-09-27T15:21:41.514Z",
      "location_count": 2,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01999946"
    },
    {
      "nct_id": "NCT07524738",
      "title": "Telemedicine XR-B for Individuals in Jail",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Opioid Use Disorder"
      ],
      "interventions": [
        {
          "name": "Extended Release Buprenorphine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Friends Research Institute, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2025-06-01",
      "completion_date": "2026-09-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-24",
      "last_synced_at": "2026-09-27T15:21:41.514Z",
      "location_count": 1,
      "location_summary": "Cumberland, Maryland",
      "locations": [
        {
          "city": "Cumberland",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07524738"
    }
  ]
}