{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Extubation+to+CPAP",
    "query": {
      "intervention": "Extubation to CPAP"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Extubation+to+CPAP&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-07T03:48:02.538Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01471431",
      "title": "Extubation Readiness Study in Very Low Birthweight Infants",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "spontaneous breathing trial",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "48 Hours",
        "maximum_age": "14 Weeks",
        "sex": "ALL",
        "summary": "48 Hours to 14 Weeks"
      },
      "enrollment_count": 81,
      "start_date": "2011-08",
      "completion_date": "2016-04",
      "has_results": false,
      "last_update_posted_date": "2016-06-07",
      "last_synced_at": "2026-09-07T03:48:02.538Z",
      "location_count": 2,
      "location_summary": "Phialdelphia, Pennsylvania • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Phialdelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01471431"
    },
    {
      "nct_id": "NCT00005774",
      "title": "Early Surfactant to Reduce Use of Mechanical Breathing in Low Birth Weight Infants",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Infant, Newborn",
        "Respiratory Distress Syndrome",
        "Respiratory Insufficiency"
      ],
      "interventions": [
        {
          "name": "Early surfactant",
          "type": "DRUG"
        },
        {
          "name": "Standard practice",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "12 Hours",
        "sex": "ALL",
        "summary": "Up to 12 Hours"
      },
      "enrollment_count": 61,
      "start_date": "2000-05",
      "completion_date": "2002-07",
      "has_results": false,
      "last_update_posted_date": "2015-06-08",
      "last_synced_at": "2026-09-07T03:48:02.538Z",
      "location_count": 13,
      "location_summary": "Birmingham, Alabama • Palo Alto, California • New Haven, Connecticut + 10 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00005774"
    },
    {
      "nct_id": "NCT02392806",
      "title": "Comparative Effectiveness Study of Bubble CPAP Devices in the NICU",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "Bubble CPAP- BabiPlus, Respiralogics",
          "type": "DEVICE"
        },
        {
          "name": "Bubble CPAP- B&B Bubbler, B&B Medical devices",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Marya Strand, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "100 Days",
        "sex": "ALL",
        "summary": "1 Day to 100 Days"
      },
      "enrollment_count": 43,
      "start_date": "2015-01",
      "completion_date": "2016-08",
      "has_results": true,
      "last_update_posted_date": "2018-03-09",
      "last_synced_at": "2026-09-07T03:48:02.538Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02392806"
    },
    {
      "nct_id": "NCT02587832",
      "title": "High Flow Nasal Cannula in Comparison With Nasal Continuous Positive Airway Pressure in the Management of Respiratory Distress Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "HHHFNC",
          "type": "DEVICE"
        },
        {
          "name": "NCPAP",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sidra Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 60,
      "start_date": "2009-07",
      "completion_date": "2012-04",
      "has_results": false,
      "last_update_posted_date": "2015-10-27",
      "last_synced_at": "2026-09-07T03:48:02.538Z",
      "location_count": 1,
      "location_summary": "Akron, Ohio",
      "locations": [
        {
          "city": "Akron",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02587832"
    },
    {
      "nct_id": "NCT00244101",
      "title": "Delivery Room Management Trial of Premature Infants at High Risk of Respiratory Distress Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Respiratory Distress Syndrome, Newborn"
      ],
      "interventions": [
        {
          "name": "PS Group",
          "type": "DRUG"
        },
        {
          "name": "NCPAP Group",
          "type": "DEVICE"
        },
        {
          "name": "ISX Group",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Vermont Oxford Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "26 Weeks",
        "maximum_age": "29 Weeks",
        "sex": "ALL",
        "summary": "26 Weeks to 29 Weeks"
      },
      "enrollment_count": 648,
      "start_date": "2003-08",
      "completion_date": "2011-06",
      "has_results": true,
      "last_update_posted_date": "2023-01-18",
      "last_synced_at": "2026-09-07T03:48:02.538Z",
      "location_count": 1,
      "location_summary": "Burlington, Vermont",
      "locations": [
        {
          "city": "Burlington",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00244101"
    },
    {
      "nct_id": "NCT01909947",
      "title": "Prediction of Extubation Readiness in Extreme Preterm Infants by the Automated Analysis of CardioRespiratory Behavior",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Prediction of Extubation Readiness"
      ],
      "interventions": [
        {
          "name": "Cardiorespiratory signal acquisition",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "McGill University Health Centre/Research Institute of the McGill University Health Centre",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 266,
      "start_date": "2013-09",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2019-04-01",
      "last_synced_at": "2026-09-07T03:48:02.538Z",
      "location_count": 2,
      "location_summary": "Detroit, Michigan • Providence, Rhode Island",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01909947"
    },
    {
      "nct_id": "NCT01440647",
      "title": "Study of Nasal Ventilation In Preterm Infants To Decrease Time on The Respirator",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bronchopulmonary Dysplasia"
      ],
      "interventions": [
        {
          "name": "Extubation to NIPPV",
          "type": "PROCEDURE"
        },
        {
          "name": "Extubation to CPAP",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Women and Infants Hospital of Rhode Island",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "48 Hours",
        "sex": "ALL",
        "summary": "Up to 48 Hours"
      },
      "enrollment_count": 34,
      "start_date": "2007-11",
      "completion_date": "2010-01",
      "has_results": true,
      "last_update_posted_date": "2013-03-12",
      "last_synced_at": "2026-09-07T03:48:02.538Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01440647"
    },
    {
      "nct_id": "NCT04507425",
      "title": "High Flow Nasal Cannula With Noninvasive Ventilation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Standard of Care - Nasal Cannula",
          "type": "OTHER"
        },
        {
          "name": "High-flow nasal cannula",
          "type": "OTHER"
        },
        {
          "name": "HFNC plus non-invasive ventilation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 6,
      "start_date": "2020-09-01",
      "completion_date": "2023-07-10",
      "has_results": false,
      "last_update_posted_date": "2023-11-21",
      "last_synced_at": "2026-09-07T03:48:02.538Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04507425"
    },
    {
      "nct_id": "NCT00609882",
      "title": "Comparison of Humidified High Flow Nasal Cannula to Nasal CPAP in Neonates",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Insufficiency"
      ],
      "interventions": [
        {
          "name": "Nasal CPAP",
          "type": "OTHER"
        },
        {
          "name": "Humidified High Flow Nasal Cannula (HHFNC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "8 Weeks",
        "sex": "ALL",
        "summary": "Up to 8 Weeks"
      },
      "enrollment_count": 420,
      "start_date": "2007-12",
      "completion_date": "2012-06",
      "has_results": false,
      "last_update_posted_date": "2013-02-06",
      "last_synced_at": "2026-09-07T03:48:02.538Z",
      "location_count": 8,
      "location_summary": "Philadelphia, Pennsylvania • Lackland Air Force Base, Texas • Ogden, Utah + 3 more",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Lackland Air Force Base",
          "state": "Texas"
        },
        {
          "city": "Ogden",
          "state": "Utah"
        },
        {
          "city": "Provo",
          "state": "Utah"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00609882"
    },
    {
      "nct_id": "NCT03266016",
      "title": "Real-time Effort Driven VENTilator Management",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ventilation Therapy; Complications",
        "Diaphragm Disease",
        "Pediatric Respiratory Diseases"
      ],
      "interventions": [
        {
          "name": "Computerized Ventilator Protocol",
          "type": "OTHER"
        },
        {
          "name": "Esophageal Manometry",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Respiratory Inductance Plethysmography (RIP)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Diaphragm Ultrasound",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Maximal Inspiratory Pressure",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Children's Hospital Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Days",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "30 Days to 18 Years"
      },
      "enrollment_count": 248,
      "start_date": "2017-10-21",
      "completion_date": "2024-06-20",
      "has_results": true,
      "last_update_posted_date": "2025-09-17",
      "last_synced_at": "2026-09-07T03:48:02.538Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03266016"
    }
  ]
}