{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=FLU+HD+vaccine&page=2", "query": { "intervention": "FLU HD vaccine", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 49, "total_pages": 5, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=FLU+HD+vaccine&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=FLU+HD+vaccine&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-02T20:09:21.913Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03658629", "title": "Phase 2 Dose and Formulation Confirmation of Quad-NIV in Older Adults", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Influenza, Human" ], "interventions": [ { "name": "NanoFlu (Quad-NIV)", "type": "BIOLOGICAL" }, { "name": "Matrix-M Adjuvant", "type": "OTHER" }, { "name": "Placebo", "type": "OTHER" }, { "name": "Fluzone HD", "type": "BIOLOGICAL" }, { "name": "Flublok Quadrivalent", "type": "BIOLOGICAL" }, { "name": "Influenza Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL", "OTHER" ], "sponsor": "Novavax", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "65 Years", "maximum_age": null, "sex": "ALL", "summary": "65 Years and older" }, "enrollment_count": 1375, "start_date": "2018-09-24", "completion_date": "2019-04-26", "has_results": true, "last_update_posted_date": "2022-11-04", "last_synced_at": "2026-10-02T20:09:21.913Z", "location_count": 14, "location_summary": "Hollywood, Florida • Savannah, Georgia • Stockbridge, Georgia + 11 more", "locations": [ { "city": "Hollywood", "state": "Florida" }, { "city": "Savannah", "state": "Georgia" }, { "city": "Stockbridge", "state": "Georgia" }, { "city": "Rockville", "state": "Maryland" }, { "city": "Norfolk", "state": "Nebraska" } ], "official_url": "https://clinicaltrials.gov/study/NCT03658629" }, { "nct_id": "NCT06029933", "title": "Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Influenza", "Community-acquired Pneumonia", "Cardiovascular Events" ], "interventions": [ { "name": "Adjuvanted Quadrivalent Inactivated Influenza Vaccine (aIIV4)", "type": "BIOLOGICAL" }, { "name": "High-Dose Quadrivalent Inactivated Influenza Vaccine (HD-IIV4)", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Kaiser Permanente", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "65 Years", "maximum_age": null, "sex": "ALL", "summary": "65 Years and older" }, "enrollment_count": 1500000, "start_date": "2023-08-17", "completion_date": "2028-05", "has_results": false, "last_update_posted_date": "2026-08-05", "last_synced_at": "2026-10-02T20:09:21.913Z", "location_count": 1, "location_summary": "Oakland, California", "locations": [ { "city": "Oakland", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06029933" }, { "nct_id": "NCT05426174", "title": "Study to Assess the Safety and Immunogenicity of Monovalent mRNA NA Vaccine in Adult Participants 18 Years of Age and Older", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Influenza Immunization", "Healthy Volunteers" ], "interventions": [ { "name": "mRNA NA vaccine", "type": "BIOLOGICAL" }, { "name": "High Dose Quadrivalent Influenza Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 233, "start_date": "2022-06-09", "completion_date": "2024-01-03", "has_results": false, "last_update_posted_date": "2025-09-15", "last_synced_at": "2026-10-02T20:09:21.913Z", "location_count": 6, "location_summary": "Huntsville, Alabama • Phoenix, Arizona • San Diego, California + 3 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "San Diego", "state": "California" }, { "city": "Melbourne", "state": "Florida" }, { "city": "Peoria", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT05426174" }, { "nct_id": "NCT05553301", "title": "Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5407 in Adult Participants18 Years of Age and Older", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Influenza Immunization" ], "interventions": [ { "name": "Quadrivalent Influenza mRNA Vaccine MRT5407", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Recombinant Influenza Vaccine", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Influenza Standard Dose Vaccine", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Influenza High-Dose Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 560, "start_date": "2022-10-03", "completion_date": "2024-01-19", "has_results": false, "last_update_posted_date": "2025-01-24", "last_synced_at": "2026-10-02T20:09:21.913Z", "location_count": 23, "location_summary": "Rolling Hills Estates, California • San Diego, California • DeLand, Florida + 16 more", "locations": [ { "city": "Rolling Hills Estates", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "DeLand", "state": "Florida" }, { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05553301" }, { "nct_id": "NCT01205581", "title": "Immunogenicity of Fluzone HD,A High Dose Influenza Vaccine, In Children With Cancer or HIV", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "HIV", "Cancer" ], "interventions": [ { "name": "Fluzone High Dose Vaccine", "type": "BIOLOGICAL" }, { "name": "Fluzone Standard Dose Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "St. Jude Children's Research Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Years", "maximum_age": "21 Years", "sex": "ALL", "summary": "3 Years to 21 Years" }, "enrollment_count": 85, "start_date": "2010-09", "completion_date": "2013-08", "has_results": true, "last_update_posted_date": "2016-09-23", "last_synced_at": "2026-10-02T20:09:21.913Z", "location_count": 1, "location_summary": "Memphis, Tennessee", "locations": [ { "city": "Memphis", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT01205581" }, { "nct_id": "NCT02500680", "title": "The Safety, Tolerance, and Immunogenicity of MAS-1-Adjuvanted Seasonal Inactivated Influenza Vaccine (MER4101)", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Influenza, Human" ], "interventions": [ { "name": "MER4101", "type": "BIOLOGICAL" }, { "name": "Inactivated Influenza Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Nova Immunotherapeutics Limited", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 102, "start_date": "2015-07", "completion_date": "2020-12", "has_results": false, "last_update_posted_date": "2019-09-06", "last_synced_at": "2026-10-02T20:09:21.913Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT02500680" }, { "nct_id": "NCT07300085", "title": "A Trial to Evaluate the Effect of CD388/MK1406 on the Immunogenicity of Fluzone® HD Vaccine (CD388.SQ.1.08/MK-1406-007)", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy Participants" ], "interventions": [ { "name": "Fluzone® High-Dose (HD) influenza vaccine", "type": "BIOLOGICAL" }, { "name": "MK-1406 Injection", "type": "COMBINATION_PRODUCT" }, { "name": "Placebo", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "BIOLOGICAL", "COMBINATION_PRODUCT" ], "sponsor": "Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "49 Years", "sex": "ALL", "summary": "18 Years to 49 Years" }, "enrollment_count": 710, "start_date": "2025-11-08", "completion_date": "2026-12-31", "has_results": false, "last_update_posted_date": "2026-08-19", "last_synced_at": "2026-10-02T20:09:21.913Z", "location_count": 4, "location_summary": "Glendale, California • Baltimore, Maryland", "locations": [ { "city": "Glendale", "state": "California" }, { "city": "Glendale", "state": "California" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT07300085" }, { "nct_id": "NCT05624606", "title": "Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5410 in Adult Participants 18 Years of Age and Older", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Influenza Immunization" ], "interventions": [ { "name": "Quadrivalent Influenza mRNA Vaccine MRT5410", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Recombinant Influenza vaccine RIV4", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Inactivated Influenza Standard Dose QIV-SD", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Inactivated Influenza High Dose QIV-HD", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 682, "start_date": "2022-11-28", "completion_date": "2024-03-28", "has_results": false, "last_update_posted_date": "2025-03-18", "last_synced_at": "2026-10-02T20:09:21.913Z", "location_count": 23, "location_summary": "Huntington Park, California • Long Beach, California • North Hollywood, California + 19 more", "locations": [ { "city": "Huntington Park", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "North Hollywood", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05624606" }, { "nct_id": "NCT06431607", "title": "A Study to Find the Dose and Assess the Immune Response and Safety of a Vaccine Against Influenza in Healthy Younger and Older Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Influenza, Human" ], "interventions": [ { "name": "F2G22B/DL001Z", "type": "BIOLOGICAL" }, { "name": "F2H23D/DL001Z-NH", "type": "BIOLOGICAL" }, { "name": "F2H23B/DL001Z-NH", "type": "BIOLOGICAL" }, { "name": "F2H23H/DL001Z", "type": "BIOLOGICAL" }, { "name": "FDQ23A-NH (Flu D-QIV)", "type": "COMBINATION_PRODUCT" }, { "name": "GSK5800544A", "type": "BIOLOGICAL" }, { "name": "Flu D-TIV", "type": "COMBINATION_PRODUCT" }, { "name": "F2H23A/DL001Z-NH", "type": "BIOLOGICAL" }, { "name": "F2H23G/DL001Z", "type": "BIOLOGICAL" }, { "name": "Fluzone HD Quadrivalent", "type": "COMBINATION_PRODUCT" }, { "name": "Fluzone HD", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "BIOLOGICAL", "COMBINATION_PRODUCT" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 845, "start_date": "2024-05-23", "completion_date": "2025-06-04", "has_results": true, "last_update_posted_date": "2026-03-10", "last_synced_at": "2026-10-02T20:09:21.913Z", "location_count": 18, "location_summary": "Hialeah, Florida • Miami, Florida • Chicago, Illinois + 14 more", "locations": [ { "city": "Hialeah", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Valparaiso", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT06431607" }, { "nct_id": "NCT05947071", "title": "High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Immunization; Infection", "Transplantation Infection", "Influenza" ], "interventions": [ { "name": "Standard Dose Quadrivalent Inactivated Influenza Vaccine", "type": "BIOLOGICAL" }, { "name": "High Dose Quadrivalent Inactivated Influenza Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "3 Years to 17 Years" }, "enrollment_count": 312, "start_date": "2024-09-26", "completion_date": "2027-09-01", "has_results": false, "last_update_posted_date": "2026-09-24", "last_synced_at": "2026-10-02T20:09:21.913Z", "location_count": 10, "location_summary": "Stanford, California • Atlanta, Georgia • Chicago, Illinois + 7 more", "locations": [ { "city": "Stanford", "state": "California" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Kansas City", "state": "Missouri" }, { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT05947071" } ] }