{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=FOLFIRI+Infusion&page=2", "query": { "intervention": "FOLFIRI Infusion", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=FOLFIRI+Infusion&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-21T20:56:12.023Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02568046", "title": "Sym004 in Combination With FOLFIRI in Metastatic Colorectal Cancer Patients", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Metastatic Colorectal Cancer" ], "interventions": [ { "name": "Sym004", "type": "DRUG" }, { "name": "FOLFIRI", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Symphogen A/S", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10, "start_date": "2016-03-15", "completion_date": "2018-05-05", "has_results": true, "last_update_posted_date": "2019-03-26", "last_synced_at": "2026-09-21T20:56:12.023Z", "location_count": 5, "location_summary": "Los Angeles, California • San Diego, California • Washington D.C., District of Columbia + 2 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Athens", "state": "Georgia" }, { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT02568046" }, { "nct_id": "NCT05678257", "title": "A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Colorectal Cancer", "Colorectal Neoplasms", "Colorectal Adenocarcinoma", "Colorectal Cancer Metastatic", "Neoplasm, Colorectal" ], "interventions": [ { "name": "Fosifloxuridine Nafalbenamide", "type": "DRUG" }, { "name": "Leucovorin", "type": "DRUG" }, { "name": "Irinotecan", "type": "DRUG" }, { "name": "Bevacizumab", "type": "BIOLOGICAL" }, { "name": "5-FU", "type": "DRUG" } ], "intervention_types": [ "DRUG", "BIOLOGICAL" ], "sponsor": "NuCana plc", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 180, "start_date": "2023-04-18", "completion_date": "2024-08-29", "has_results": true, "last_update_posted_date": "2025-09-12", "last_synced_at": "2026-09-21T20:56:12.023Z", "location_count": 16, "location_summary": "Newark, Delaware • Washington D.C., District of Columbia • Gainesville, Florida + 12 more", "locations": [ { "city": "Newark", "state": "Delaware" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Iowa City", "state": "Iowa" }, { "city": "Wichita", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05678257" }, { "nct_id": "NCT03368859", "title": "A Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and Bevacizumab", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cancer" ], "interventions": [ { "name": "Leucovorin", "type": "DRUG" }, { "name": "Fluorouracil - bolus", "type": "DRUG" }, { "name": "Bevacizumab", "type": "DRUG" }, { "name": "Fluorouracil - infusion", "type": "DRUG" }, { "name": "ABT-165", "type": "DRUG" }, { "name": "Irinotecan", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 70, "start_date": "2018-03-20", "completion_date": "2019-12-18", "has_results": true, "last_update_posted_date": "2021-02-09", "last_synced_at": "2026-09-21T20:56:12.023Z", "location_count": 46, "location_summary": "Chandler, Arizona • Fayetteville, Arkansas • Duarte, California + 39 more", "locations": [ { "city": "Chandler", "state": "Arizona" }, { "city": "Fayetteville", "state": "Arkansas" }, { "city": "Duarte", "state": "California" }, { "city": "Fullerton", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03368859" }, { "nct_id": "NCT06501989", "title": "Study of 5-fluorouracil (5-FU) in Patients With Metastatic Colorectal Cancer", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Metastatic Colorectal Cancer" ], "interventions": [ { "name": "Biweekly 5-FLUOROURACIL (5-FU)", "type": "DRUG" }, { "name": "Biweekly Modified FOLFOX6", "type": "DRUG" }, { "name": "Biweekly FOLFIRI", "type": "DRUG" }, { "name": "mFOLFOXIRI", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Inova Health Care Services", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2025-09-19", "completion_date": "2025-09-19", "has_results": false, "last_update_posted_date": "2026-02-11", "last_synced_at": "2026-09-21T20:56:12.023Z", "location_count": 1, "location_summary": "Falls Church, Virginia", "locations": [ { "city": "Falls Church", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT06501989" }, { "nct_id": "NCT07011576", "title": "A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Colon Cancer", "Rectal Cancer", "Colorectal Cancer", "Colorectal Cancer (CRC)" ], "interventions": [ { "name": "fruquintinib", "type": "DRUG" }, { "name": "FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "SCRI Development Innovations, LLC", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2025-09-29", "completion_date": "2027-06", "has_results": false, "last_update_posted_date": "2026-06-12", "last_synced_at": "2026-09-21T20:56:12.023Z", "location_count": 14, "location_summary": "Denver, Colorado • Arlington Heights, Illinois • Columbia, Maryland + 11 more", "locations": [ { "city": "Denver", "state": "Colorado" }, { "city": "Arlington Heights", "state": "Illinois" }, { "city": "Columbia", "state": "Maryland" }, { "city": "Maple Grove", "state": "Minnesota" }, { "city": "Columbia", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT07011576" }, { "nct_id": "NCT05087992", "title": "A Study to Find the Best Dose of BI 905711 in Combination With Chemotherapy and to Test Whether This Dose Helps People With Advanced Gastrointestinal Cancers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Gastrointestinal Cancer, Metastatic" ], "interventions": [ { "name": "BI 905711", "type": "DRUG" }, { "name": "FOLFIRI", "type": "DRUG" }, { "name": "Bevacizumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 13, "start_date": "2021-11-24", "completion_date": "2023-11-14", "has_results": true, "last_update_posted_date": "2025-02-19", "last_synced_at": "2026-09-21T20:56:12.023Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05087992" }, { "nct_id": "NCT00561470", "title": "Aflibercept Versus Placebo in Combination With Irinotecan and 5-FU in the Treatment of Patients With Metastatic Colorectal Cancer After Failure of an Oxaliplatin Based Regimen", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Colorectal Neoplasms", "Neoplasm Metastasis" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Aflibercept (ziv-aflibercept, AVE0005, VEGF trap, ZALTRAP®)", "type": "DRUG" }, { "name": "FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sanofi", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1226, "start_date": "2007-11", "completion_date": "2012-06", "has_results": true, "last_update_posted_date": "2012-09-28", "last_synced_at": "2026-09-21T20:56:12.023Z", "location_count": 87, "location_summary": "Birmingham, Alabama • Muscle Shoals, Alabama • Hot Springs, Arizona + 68 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Muscle Shoals", "state": "Alabama" }, { "city": "Hot Springs", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Fountain Valley", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00561470" }, { "nct_id": "NCT07201519", "title": "Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Colorectal Cancer Metastatic", "Intrahepatic Cholangiocarcinoma" ], "interventions": [ { "name": "Hepatic Artery Infusion Pump (HAIP)", "type": "DEVICE" }, { "name": "Standard Treatment", "type": "PROCEDURE" }, { "name": "Community Treatment", "type": "PROCEDURE" }, { "name": "Systemic Chemotherapy Standard of Care", "type": "DRUG" }, { "name": "Standard Of Care targeting driver mutations", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "PROCEDURE", "DRUG" ], "sponsor": "Michael J Cavnar, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 80, "start_date": "2026-01-23", "completion_date": "2030-02", "has_results": false, "last_update_posted_date": "2026-02-04", "last_synced_at": "2026-09-21T20:56:12.023Z", "location_count": 1, "location_summary": "Lexington, Kentucky", "locations": [ { "city": "Lexington", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT07201519" }, { "nct_id": "NCT03692429", "title": "alloSHRINK - Standard cHemotherapy Regimen and Immunotherapy With Allogeneic NKG2D-based CYAD-101 Chimeric Antigen Receptor T-cells", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Unresectable Metastatic Colorectal Cancer" ], "interventions": [ { "name": "CYAD-101", "type": "DRUG" }, { "name": "FOLFOX", "type": "DRUG" }, { "name": "FOLFIRI", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Celyad Oncology SA", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 49, "start_date": "2018-11-28", "completion_date": "2036-02-17", "has_results": false, "last_update_posted_date": "2020-11-20", "last_synced_at": "2026-09-21T20:56:12.023Z", "location_count": 1, "location_summary": "Tampa, Florida", "locations": [ { "city": "Tampa", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03692429" }, { "nct_id": "NCT03665441", "title": "Study of Eryaspase in Combination With Chemotherapy Versus Chemotherapy Alone as 2nd-Line Treatment in PAC", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pancreatic Adenocarcinoma" ], "interventions": [ { "name": "eryaspase", "type": "DRUG" }, { "name": "Gemcitabine plus Abraxane", "type": "DRUG" }, { "name": "Irinotecan plus 5-FU plus leucovorin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "ERYtech Pharma", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 512, "start_date": "2018-09-15", "completion_date": "2022-01-18", "has_results": true, "last_update_posted_date": "2022-10-18", "last_synced_at": "2026-09-21T20:56:12.023Z", "location_count": 14, "location_summary": "Scottsdale, Arizona • Fullerton, California • Sacramento, California + 11 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Fullerton", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Boca Raton", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03665441" } ] }