{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fixed+Appliance+Orthodontic+Treatment",
    "query": {
      "intervention": "Fixed Appliance Orthodontic Treatment"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 19,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fixed+Appliance+Orthodontic+Treatment&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-29T15:28:06.858Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04556448",
      "title": "RCT Comparing Invisalign and Traditional Orthodontic Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Malocclusion, Angle Class II"
      ],
      "interventions": [
        {
          "name": "Aligners",
          "type": "OTHER"
        },
        {
          "name": "Clear braces",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Texas A&M University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "17 Years and older"
      },
      "enrollment_count": 78,
      "start_date": "2013-01-01",
      "completion_date": "2019-03-01",
      "has_results": false,
      "last_update_posted_date": "2020-09-21",
      "last_synced_at": "2026-09-29T15:28:06.858Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04556448"
    },
    {
      "nct_id": "NCT07164989",
      "title": "Motivational Interviewing to Improve Oral Hygiene in Adolescent Orthodontic Patients",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingivitis",
        "DMFT Index",
        "Dental Plaque Index",
        "Oral Hygiene Education Methods",
        "Oral Hygiene Reinforcement During Fixed Orthodontic Treatment",
        "Motivational Interview, OHI"
      ],
      "interventions": [
        {
          "name": "Motivational Interviewing-Based Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Oral Health Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "14 Years to 19 Years"
      },
      "enrollment_count": 50,
      "start_date": "2025-10-28",
      "completion_date": "2026-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-03",
      "last_synced_at": "2026-09-29T15:28:06.858Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07164989"
    },
    {
      "nct_id": "NCT02267837",
      "title": "OrthoPulse™ and Its Effect on the Rate of Orthodontic Tooth Alignment: A Pilot Feasibility Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Malocclusion"
      ],
      "interventions": [
        {
          "name": "OrthoPulse™",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Biolux Research Holdings, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "11 Years to 40 Years"
      },
      "enrollment_count": 20,
      "start_date": "2012-12",
      "completion_date": "2013-12",
      "has_results": true,
      "last_update_posted_date": "2018-08-27",
      "last_synced_at": "2026-09-29T15:28:06.858Z",
      "location_count": 1,
      "location_summary": "Suwanee, Georgia",
      "locations": [
        {
          "city": "Suwanee",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02267837"
    },
    {
      "nct_id": "NCT01720797",
      "title": "Alveolar Microperforation for Inflammation-Enhanced Tooth Movement During Orthodontic Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Malocclusion"
      ],
      "interventions": [
        {
          "name": "Micro-osteoperforation",
          "type": "DEVICE"
        },
        {
          "name": "Anesthestic",
          "type": "DRUG"
        },
        {
          "name": "Chlorhexidine",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 21,
      "start_date": "2013-02",
      "completion_date": "2015-04",
      "has_results": true,
      "last_update_posted_date": "2015-06-19",
      "last_synced_at": "2026-09-29T15:28:06.858Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01720797"
    },
    {
      "nct_id": "NCT07217756",
      "title": "Impact of Increased Body Mass Index on Adolescent Fixed Orthodontic Treatment. A Prospective Longitudinal Study",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Obesity & Overweight",
        "Orthodontic Treatment"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "12 Years to 18 Years"
      },
      "enrollment_count": 52,
      "start_date": "2022-04-22",
      "completion_date": "2026-11-01",
      "has_results": false,
      "last_update_posted_date": "2025-10-20",
      "last_synced_at": "2026-09-29T15:28:06.858Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07217756"
    },
    {
      "nct_id": "NCT02267811",
      "title": "The Effect of OrthoPulse™ on the Rate of Orthodontic Tooth Movement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Malocclusion"
      ],
      "interventions": [
        {
          "name": "Orthodontic Treatment",
          "type": "OTHER"
        },
        {
          "name": "OrthoPulse™",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Biolux Research Holdings, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "11 Years to 60 Years"
      },
      "enrollment_count": 33,
      "start_date": "2013-10",
      "completion_date": "2016-06",
      "has_results": true,
      "last_update_posted_date": "2019-05-21",
      "last_synced_at": "2026-09-29T15:28:06.858Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02267811"
    },
    {
      "nct_id": "NCT04002999",
      "title": "Precision Orthodontics: Virtual Treatment Planning for Orthodontic Braces",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Malocclusion",
        "Malocclusion, Angle's Class"
      ],
      "interventions": [
        {
          "name": "3D printed ceramic bracket and tray",
          "type": "DEVICE"
        },
        {
          "name": "Stock ceramic bracket + 3D printed tray",
          "type": "DEVICE"
        },
        {
          "name": "Stock bracket, no tray",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Harvard School of Dental Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "11 Years to 65 Years"
      },
      "enrollment_count": 51,
      "start_date": "2019-08-30",
      "completion_date": "2021-05",
      "has_results": false,
      "last_update_posted_date": "2020-02-12",
      "last_synced_at": "2026-09-29T15:28:06.858Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04002999"
    },
    {
      "nct_id": "NCT04347018",
      "title": "BRIUS Vs FFA Efficiency",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Malocclusion",
        "Angle Class II",
        "Angle Class I",
        "Crowding, Tooth"
      ],
      "interventions": [
        {
          "name": "BRIUS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "State University of New York at Buffalo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "10 Years to 17 Years"
      },
      "enrollment_count": 13,
      "start_date": "2020-07-06",
      "completion_date": "2022-06-17",
      "has_results": true,
      "last_update_posted_date": "2024-10-04",
      "last_synced_at": "2026-09-29T15:28:06.858Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04347018"
    },
    {
      "nct_id": "NCT02267824",
      "title": "The Effects of Extraoral Photobiomodulation on the Rate of Orthodontic Alignment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Malocclusion"
      ],
      "interventions": [
        {
          "name": "Extraoral OrthoPulse® PBM",
          "type": "DEVICE"
        },
        {
          "name": "Fixed Orthodontic Appliance Treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Biolux Research Holdings, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "11 Years to 40 Years"
      },
      "enrollment_count": 101,
      "start_date": "2010-12",
      "completion_date": "2013-03",
      "has_results": true,
      "last_update_posted_date": "2018-08-27",
      "last_synced_at": "2026-09-29T15:28:06.858Z",
      "location_count": 2,
      "location_summary": "Birmingham, Alabama • Suwanee, Georgia",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Suwanee",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02267824"
    },
    {
      "nct_id": "NCT06616207",
      "title": "Topical 10% Povidone-Iodine in Preventing White Spots",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "White Spot Lesions",
        "Gingival Inflammation and Bleeding"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Povidone-iodine solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "10 Years to 17 Years"
      },
      "enrollment_count": 80,
      "start_date": "2024-09-13",
      "completion_date": "2027-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-16",
      "last_synced_at": "2026-09-29T15:28:06.858Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06616207"
    }
  ]
}