{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fixed+Orthodontic+Appliance+Treatment",
    "query": {
      "intervention": "Fixed Orthodontic Appliance Treatment"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 41,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fixed+Orthodontic+Appliance+Treatment&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-29T14:01:58.808Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03260699",
      "title": "Economic and Functional Impact of Peri-Operative Bracing for Primary Total Knee Arthroplasty (TKA)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthropathy of Knee"
      ],
      "interventions": [
        {
          "name": "OCSI Rehabilitator brace",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 9,
      "start_date": "2017-10-05",
      "completion_date": "2018-01-01",
      "has_results": true,
      "last_update_posted_date": "2019-10-09",
      "last_synced_at": "2026-09-29T14:01:58.808Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03260699"
    },
    {
      "nct_id": "NCT03494647",
      "title": "Comparison of Braces for Treatment of Sever's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sever's Disease"
      ],
      "interventions": [
        {
          "name": "Cheetah Heel Cup",
          "type": "DEVICE"
        },
        {
          "name": "The X Brace",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "8 Years to 14 Years"
      },
      "enrollment_count": 43,
      "start_date": "2018-04-18",
      "completion_date": "2021-11-21",
      "has_results": true,
      "last_update_posted_date": "2022-05-25",
      "last_synced_at": "2026-09-29T14:01:58.808Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03494647"
    },
    {
      "nct_id": "NCT04556448",
      "title": "RCT Comparing Invisalign and Traditional Orthodontic Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Malocclusion, Angle Class II"
      ],
      "interventions": [
        {
          "name": "Aligners",
          "type": "OTHER"
        },
        {
          "name": "Clear braces",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Texas A&M University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "17 Years and older"
      },
      "enrollment_count": 78,
      "start_date": "2013-01-01",
      "completion_date": "2019-03-01",
      "has_results": false,
      "last_update_posted_date": "2020-09-21",
      "last_synced_at": "2026-09-29T14:01:58.808Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04556448"
    },
    {
      "nct_id": "NCT04500041",
      "title": "Casting vs Bracing for Idiopathic Early-Onset Scoliosis",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Scoliosis Idiopathic",
        "Early-Onset Scoliosis Deformity of Spine"
      ],
      "interventions": [
        {
          "name": "Casting",
          "type": "PROCEDURE"
        },
        {
          "name": "Bracing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": "36 Months",
        "sex": "ALL",
        "summary": "12 Months to 36 Months"
      },
      "enrollment_count": 71,
      "start_date": "2021-02-09",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-13",
      "last_synced_at": "2026-09-29T14:01:58.808Z",
      "location_count": 24,
      "location_summary": "Little Rock, Arkansas • Aurora, Colorado • Wilmington, Delaware + 18 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Wilmington",
          "state": "Delaware"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04500041"
    },
    {
      "nct_id": "NCT02257229",
      "title": "Prospective Evaluation of Treatment for Clubfoot",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Clubfoot Deformity"
      ],
      "interventions": [
        {
          "name": "Surgical",
          "type": "PROCEDURE"
        },
        {
          "name": "Non-Surgical",
          "type": "PROCEDURE"
        },
        {
          "name": "Non-surgical + surgical",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Texas Scottish Rite Hospital for Children",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 2500,
      "start_date": "2005-08",
      "completion_date": "2029-09",
      "has_results": false,
      "last_update_posted_date": "2025-05-04",
      "last_synced_at": "2026-09-29T14:01:58.808Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02257229"
    },
    {
      "nct_id": "NCT04781621",
      "title": "Foundational Ingredients of Robotic Gait Training for People With Spinal Cord Injury During Inpatient Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries"
      ],
      "interventions": [
        {
          "name": "Robotic Gait Training",
          "type": "DEVICE"
        },
        {
          "name": "Usual Care Gait Training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Baylor Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "16 Years to 85 Years"
      },
      "enrollment_count": 115,
      "start_date": "2021-04-12",
      "completion_date": "2024-03-08",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-09-29T14:01:58.808Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04781621"
    },
    {
      "nct_id": "NCT07164989",
      "title": "Motivational Interviewing to Improve Oral Hygiene in Adolescent Orthodontic Patients",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingivitis",
        "DMFT Index",
        "Dental Plaque Index",
        "Oral Hygiene Education Methods",
        "Oral Hygiene Reinforcement During Fixed Orthodontic Treatment",
        "Motivational Interview, OHI"
      ],
      "interventions": [
        {
          "name": "Motivational Interviewing-Based Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Oral Health Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "14 Years to 19 Years"
      },
      "enrollment_count": 50,
      "start_date": "2025-10-28",
      "completion_date": "2026-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-03",
      "last_synced_at": "2026-09-29T14:01:58.808Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07164989"
    },
    {
      "nct_id": "NCT05653206",
      "title": "Incomplete Cervical SCI Without Instability",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cervical Spinal Cord Injury"
      ],
      "interventions": [
        {
          "name": "Nonsurgical treatment",
          "type": "PROCEDURE"
        },
        {
          "name": "Surgical treatment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "AO Foundation, AO Spine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 50,
      "start_date": "2023-12-11",
      "completion_date": "2027-08-18",
      "has_results": false,
      "last_update_posted_date": "2026-02-24",
      "last_synced_at": "2026-09-29T14:01:58.808Z",
      "location_count": 3,
      "location_summary": "San Francisco, California • Baltimore, Maryland • Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05653206"
    },
    {
      "nct_id": "NCT04533711",
      "title": "Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP) (R33)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "OA-PCP Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Attention Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 240,
      "start_date": "2020-11-30",
      "completion_date": "2023-12-04",
      "has_results": true,
      "last_update_posted_date": "2024-10-24",
      "last_synced_at": "2026-09-29T14:01:58.808Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04533711"
    },
    {
      "nct_id": "NCT02267837",
      "title": "OrthoPulse™ and Its Effect on the Rate of Orthodontic Tooth Alignment: A Pilot Feasibility Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Malocclusion"
      ],
      "interventions": [
        {
          "name": "OrthoPulse™",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Biolux Research Holdings, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "11 Years to 40 Years"
      },
      "enrollment_count": 20,
      "start_date": "2012-12",
      "completion_date": "2013-12",
      "has_results": true,
      "last_update_posted_date": "2018-08-27",
      "last_synced_at": "2026-09-29T14:01:58.808Z",
      "location_count": 1,
      "location_summary": "Suwanee, Georgia",
      "locations": [
        {
          "city": "Suwanee",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02267837"
    }
  ]
}