{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Flavor+additives",
    "query": {
      "intervention": "Flavor additives"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 293,
    "total_pages": 30,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Flavor+additives&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-09T23:51:55.729Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03540693",
      "title": "Fat Taste Sensory Study",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bariatric Surgery Candidate",
        "Bariatric Surgical Procedure"
      ],
      "interventions": [
        {
          "name": "RYGB",
          "type": "PROCEDURE"
        },
        {
          "name": "SG",
          "type": "PROCEDURE"
        },
        {
          "name": "LAGB",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Illinois at Urbana-Champaign",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 105,
      "start_date": "2018-04-06",
      "completion_date": "2023-07-06",
      "has_results": false,
      "last_update_posted_date": "2021-04-28",
      "last_synced_at": "2026-09-09T23:51:55.729Z",
      "location_count": 1,
      "location_summary": "Urbana, Illinois",
      "locations": [
        {
          "city": "Urbana",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03540693"
    },
    {
      "nct_id": "NCT00808470",
      "title": "Micronutrients to Prevent Noise-induced Hearing Loss",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Noise-Induced Hearing Loss"
      ],
      "interventions": [
        {
          "name": "beta-carotene, vitamins C and E, magnesium",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 72,
      "start_date": "2008-10",
      "completion_date": "2013-12",
      "has_results": true,
      "last_update_posted_date": "2017-05-19",
      "last_synced_at": "2026-09-09T23:51:55.729Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00808470"
    },
    {
      "nct_id": "NCT02018237",
      "title": "High Fructose Corn Syrup",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nonalcoholic Fatty Liver Disease",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "High fructose corn syrup diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard diet (low in high fructose corn syrup)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 47,
      "start_date": "2012-03",
      "completion_date": "2016-03",
      "has_results": false,
      "last_update_posted_date": "2017-03-27",
      "last_synced_at": "2026-09-09T23:51:55.729Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02018237"
    },
    {
      "nct_id": "NCT06467812",
      "title": "Fluid Loading Countermeasures",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Salt Tablets",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Electrolyte Solution",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "National Aeronautics and Space Administration (NASA)",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "25 Years to 55 Years"
      },
      "enrollment_count": 15,
      "start_date": "2022-04-01",
      "completion_date": "2024-10",
      "has_results": false,
      "last_update_posted_date": "2024-07-10",
      "last_synced_at": "2026-09-09T23:51:55.729Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06467812"
    },
    {
      "nct_id": "NCT01427907",
      "title": "Equivalence of Calcium Acetate Oral Solution and Sevelamer Carbonate Tablets in Hemodialysis Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Chronic Kidney Disease"
      ],
      "interventions": [
        {
          "name": "Calcium acetate oral solution (COS)",
          "type": "DRUG"
        },
        {
          "name": "Sevelamer carbonate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Fresenius Medical Care North America",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 38,
      "start_date": "2011-09",
      "completion_date": "2012-07",
      "has_results": true,
      "last_update_posted_date": "2016-01-14",
      "last_synced_at": "2026-09-09T23:51:55.729Z",
      "location_count": 4,
      "location_summary": "New Haven, Connecticut • North Haven, Connecticut • New York, New York",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "North Haven",
          "state": "Connecticut"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01427907"
    },
    {
      "nct_id": "NCT05439421",
      "title": "Consumer Perceptions of Waterpipe Tobacco Packaging and Digital Marketing Claims",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Waterpipe Tobacco Smoking"
      ],
      "interventions": [
        {
          "name": "Package/Advertisement With Claim",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Package/Advertisement Without Claim",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "29 Years",
        "sex": "ALL",
        "summary": "18 Years to 29 Years"
      },
      "enrollment_count": 1507,
      "start_date": "2022-10-25",
      "completion_date": "2022-11-23",
      "has_results": true,
      "last_update_posted_date": "2024-03-19",
      "last_synced_at": "2026-09-09T23:51:55.729Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05439421"
    },
    {
      "nct_id": "NCT03905928",
      "title": "Establishing the Effect of Flavor on the Addictive Potential of Electronic Cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Dependence"
      ],
      "interventions": [
        {
          "name": "Nicotine Containing ECIG with tobacco flavor",
          "type": "OTHER"
        },
        {
          "name": "Nicotine Containing ECIG with Strawberry Vanilla Flavor",
          "type": "OTHER"
        },
        {
          "name": "Placebo ECIG with Tobacco Flavor",
          "type": "OTHER"
        },
        {
          "name": "Placebo ECIG with Strawberry Vanilla Flavor",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 19,
      "start_date": "2019-11-04",
      "completion_date": "2024-04-30",
      "has_results": true,
      "last_update_posted_date": "2025-06-22",
      "last_synced_at": "2026-09-09T23:51:55.729Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03905928"
    },
    {
      "nct_id": "NCT07217834",
      "title": "Effects of a Glycerol-Electrolyte Beverage on Fluid Balance in Healthy Euhydrated Men and Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fluid Balance"
      ],
      "interventions": [
        {
          "name": "Placebo beverage, kiwi-strawberry flavor",
          "type": "OTHER"
        },
        {
          "name": "Experimental glycerol beverage, kiwi-strawberry flavor",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "PepsiCo Global R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 27,
      "start_date": "2025-10-01",
      "completion_date": "2025-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-15",
      "last_synced_at": "2026-09-09T23:51:55.729Z",
      "location_count": 1,
      "location_summary": "Bradenton, Florida",
      "locations": [
        {
          "city": "Bradenton",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07217834"
    },
    {
      "nct_id": "NCT01909635",
      "title": "Assessment of Thoughts and Feelings Occurring During and After a Meal",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Behavior and Behavior Mechanisms",
        "Food Habits",
        "Feeding Behavior",
        "Behavior"
      ],
      "interventions": [
        {
          "name": "Food Feelings",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Other Feelings",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The University of Tennessee, Knoxville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 35 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2014-07",
      "completion_date": "2014-07",
      "has_results": false,
      "last_update_posted_date": "2018-03-29",
      "last_synced_at": "2026-09-09T23:51:55.729Z",
      "location_count": 1,
      "location_summary": "Knoxville, Tennessee",
      "locations": [
        {
          "city": "Knoxville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01909635"
    },
    {
      "nct_id": "NCT04640285",
      "title": "Nicotine Uptake, Measures of Abuse Liability, and Puffing Topography With Use of RELX ENDS Products by Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use"
      ],
      "interventions": [
        {
          "name": "RELX ENDS Tobacco Flavor",
          "type": "OTHER"
        },
        {
          "name": "RELX ENDS Menthol Flavor",
          "type": "OTHER"
        },
        {
          "name": "Usual Brand Cigarette",
          "type": "OTHER"
        },
        {
          "name": "Nicorette White Ice Mint nicotine polacrilex gum",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Cheerain HK Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "59 Years",
        "sex": "ALL",
        "summary": "22 Years to 59 Years"
      },
      "enrollment_count": 41,
      "start_date": "2020-11-03",
      "completion_date": "2021-03-19",
      "has_results": false,
      "last_update_posted_date": "2021-03-24",
      "last_synced_at": "2026-09-09T23:51:55.729Z",
      "location_count": 1,
      "location_summary": "Overland Park, Kansas",
      "locations": [
        {
          "city": "Overland Park",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04640285"
    }
  ]
}