{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Flow-mediated+dilation+testing",
    "query": {
      "intervention": "Flow-mediated dilation testing"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 24,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Flow-mediated+dilation+testing&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-02T09:23:37.074Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03269721",
      "title": "COPD-Related Physiology and the Brain",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pulmonary Disease, Chronic Obstructive (COPD)",
        "Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Neuropsychological Assessment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Spirometry",
          "type": "PROCEDURE"
        },
        {
          "name": "Arterial Blood Gas",
          "type": "PROCEDURE"
        },
        {
          "name": "Diffusion Capacity of the Lung for Carbon Monoxide",
          "type": "PROCEDURE"
        },
        {
          "name": "6 Minute Walk Test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Systemic Vascular Measures",
          "type": "PROCEDURE"
        },
        {
          "name": "Blood Biomarkers",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Symptom Questionnaire Measures",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Brain MRI",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "PROCEDURE",
        "DIAGNOSTIC_TEST",
        "BIOLOGICAL"
      ],
      "sponsor": "Karin Hoth",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "30 Years to 85 Years"
      },
      "enrollment_count": 170,
      "start_date": "2017-05-01",
      "completion_date": "2025-04-30",
      "has_results": false,
      "last_update_posted_date": "2025-12-24",
      "last_synced_at": "2026-09-02T09:23:37.074Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03269721"
    },
    {
      "nct_id": "NCT03081390",
      "title": "Migraine and CVD Risk in Women",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Migraine"
      ],
      "interventions": [
        {
          "name": "Mixed meal tolerance testing",
          "type": "OTHER"
        },
        {
          "name": "Skin conductance & cold pressor test",
          "type": "OTHER"
        },
        {
          "name": "Flow-mediated dilation testing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 35 Years · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2017-04-01",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-09-08",
      "last_synced_at": "2026-09-02T09:23:37.074Z",
      "location_count": 2,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03081390"
    },
    {
      "nct_id": "NCT07244809",
      "title": "Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adverse Childhood Experience",
        "Endothelial Function (FMD)",
        "Endothelial Injury",
        "Mitochondrial Function",
        "Oxidative Stress",
        "Psychosocial Influence on Cardiovascular Disease"
      ],
      "interventions": [
        {
          "name": "Mitoquinone mesylate (MitoQ)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "29 Years",
        "sex": "ALL",
        "summary": "18 Years to 29 Years"
      },
      "enrollment_count": 300,
      "start_date": "2025-10-13",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-24",
      "last_synced_at": "2026-09-02T09:23:37.074Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07244809"
    },
    {
      "nct_id": "NCT03894527",
      "title": "Impact of Acute Exercise on Vascular Insulin Sensitivity in Metabolic Syndrome",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Metabolic Syndrome",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Single Bout of Exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control Condition",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 16,
      "start_date": "2019-02-18",
      "completion_date": "2020-01-31",
      "has_results": false,
      "last_update_posted_date": "2019-03-28",
      "last_synced_at": "2026-09-02T09:23:37.074Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03894527"
    },
    {
      "nct_id": "NCT01262222",
      "title": "Patients Undergoing Major Cancer Surgery: Incidence and Predictive Value for Postoperative Cardiac Events",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "High Risk for Postoperative Cardiovascular Events"
      ],
      "interventions": [
        {
          "name": "endothelial function testing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 67,
      "start_date": "2010-12",
      "completion_date": "2018-07-11",
      "has_results": false,
      "last_update_posted_date": "2018-07-13",
      "last_synced_at": "2026-09-02T09:23:37.074Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01262222"
    },
    {
      "nct_id": "NCT02598674",
      "title": "Severe Sepsis in Children - IMPRESS-C",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Kidney Injury",
        "Chronic Kidney Disease",
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Iodohippurate",
          "type": "DRUG"
        },
        {
          "name": "24 hour ambulatory Blood Pressure",
          "type": "PROCEDURE"
        },
        {
          "name": "Peripheral Arterial Tonometry",
          "type": "PROCEDURE"
        },
        {
          "name": "Pulse Wave Velocity",
          "type": "PROCEDURE"
        },
        {
          "name": "Gadolinium",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "7 Years to 17 Years"
      },
      "enrollment_count": 0,
      "start_date": "2019-10",
      "completion_date": "2021-09",
      "has_results": false,
      "last_update_posted_date": "2020-12-09",
      "last_synced_at": "2026-09-02T09:23:37.074Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02598674"
    },
    {
      "nct_id": "NCT04121741",
      "title": "Singing and Cardiovascular Health in Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Diseases",
        "Cardiovascular Risk Factor",
        "Cardiovascular Health"
      ],
      "interventions": [
        {
          "name": "Singing with Music Therapist",
          "type": "OTHER"
        },
        {
          "name": "Singing with Guided Video",
          "type": "OTHER"
        },
        {
          "name": "Control Arm",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "55 Years to 79 Years"
      },
      "enrollment_count": 65,
      "start_date": "2020-01-17",
      "completion_date": "2023-08-18",
      "has_results": true,
      "last_update_posted_date": "2025-02-05",
      "last_synced_at": "2026-09-02T09:23:37.074Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04121741"
    },
    {
      "nct_id": "NCT06930638",
      "title": "MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Stroke"
      ],
      "interventions": [
        {
          "name": "Ischemic Conditioning",
          "type": "DEVICE"
        },
        {
          "name": "Antioxidant Supplement",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 30,
      "start_date": "2025-07-22",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-09-25",
      "last_synced_at": "2026-09-02T09:23:37.074Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06930638"
    },
    {
      "nct_id": "NCT01964807",
      "title": "Cardiovascular Assessment of the Effects of Tobacco and Nicotine Delivery Products",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adverse Effect of Other Agents Primarily Affecting the Cardiovascular System, Initial Encounter"
      ],
      "interventions": [
        {
          "name": "Cigarette, NIDA test type with 16.6 mg nicotine",
          "type": "OTHER"
        },
        {
          "name": "Cigarette, NIDA test type with <0.45 mg nicotine",
          "type": "OTHER"
        },
        {
          "name": "Electronic cigarette with 18 mg/ml nicotine",
          "type": "OTHER"
        },
        {
          "name": "Electronic Cigarette with no nicotine",
          "type": "OTHER"
        },
        {
          "name": "Moist snuff",
          "type": "OTHER"
        },
        {
          "name": "Sham Smoking",
          "type": "OTHER"
        },
        {
          "name": "Secondhand cigarette smoke (SHS)",
          "type": "OTHER"
        },
        {
          "name": "Conditioned, filtered air",
          "type": "OTHER"
        },
        {
          "name": "Sham Moist Snuff",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 81,
      "start_date": "2013-11-03",
      "completion_date": "2021-05-31",
      "has_results": false,
      "last_update_posted_date": "2021-12-27",
      "last_synced_at": "2026-09-02T09:23:37.074Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01964807"
    },
    {
      "nct_id": "NCT02230202",
      "title": "Endothelial Microparticles: A Novel Marker of Vascular Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Kidney Disease"
      ],
      "interventions": [
        {
          "name": "Flow-mediated dilation",
          "type": "OTHER"
        },
        {
          "name": "single blood draw",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 90,
      "start_date": "2014-09",
      "completion_date": "2016-03",
      "has_results": false,
      "last_update_posted_date": "2018-02-28",
      "last_synced_at": "2026-09-02T09:23:37.074Z",
      "location_count": 2,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02230202"
    }
  ]
}