{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fluconazole+placebo", "query": { "intervention": "Fluconazole placebo" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 25, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fluconazole+placebo&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-13T14:35:16.686Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02765256", "title": "Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Crohn's Disease" ], "interventions": [ { "name": "Fluconazole", "type": "DRUG" }, { "name": "Vancomycin", "type": "DRUG" }, { "name": "Neomycin", "type": "DRUG" }, { "name": "Ciprofloxacin", "type": "DRUG" }, { "name": "Polyethylene Glycol 3350", "type": "DRUG" }, { "name": "Promethazine", "type": "DRUG" }, { "name": "Fluconazole placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 8, "start_date": "2016-08", "completion_date": "2018-12", "has_results": true, "last_update_posted_date": "2024-02-06", "last_synced_at": "2026-09-13T14:35:16.686Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02765256" }, { "nct_id": "NCT02663674", "title": "Efficacy Study of Fluconazole to Treat Coccidioidomycosis Pneumonia (Valley Fever)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Coccidioidomycosis" ], "interventions": [ { "name": "Fluconazole", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 72, "start_date": "2015-12-29", "completion_date": "2018-07-31", "has_results": true, "last_update_posted_date": "2019-07-05", "last_synced_at": "2026-09-13T14:35:16.686Z", "location_count": 9, "location_summary": "Phoenix, Arizona • Scottsdale, Arizona • Tucson, Arizona + 3 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT02663674" }, { "nct_id": "NCT01505179", "title": "The Effects of Ranolazine on Exercise Capacity in Patients With Heart Failure With Preserved Ejection Fraction", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Heart Failure With Preserved Ejection Fraction" ], "interventions": [ { "name": "Ranolazine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, San Diego", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10, "start_date": "2011-02", "completion_date": "2015-01", "has_results": true, "last_update_posted_date": "2020-01-18", "last_synced_at": "2026-09-13T14:35:16.686Z", "location_count": 1, "location_summary": "San Diego, California", "locations": [ { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01505179" }, { "nct_id": "NCT05421858", "title": "A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Candidemia", "Candidiasis, Invasive" ], "interventions": [ { "name": "Fosmanogepix", "type": "DRUG" }, { "name": "Caspofungin", "type": "DRUG" }, { "name": "Fluconazole", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Basilea Pharmaceutica", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 450, "start_date": "2024-12-11", "completion_date": "2028-01-30", "has_results": false, "last_update_posted_date": "2026-08-28", "last_synced_at": "2026-09-13T14:35:16.686Z", "location_count": 23, "location_summary": "Birmingham, Alabama • Duarte, California • Los Angeles, California + 17 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Duarte", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT05421858" }, { "nct_id": "NCT00012467", "title": "Safety and Antifungal Activity of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Cryptococcal Meningitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Meningitis, Cryptococcal", "HIV Infections" ], "interventions": [ { "name": "Itraconazole", "type": "DRUG" }, { "name": "Flucytosine", "type": "DRUG" }, { "name": "Fluconazole", "type": "DRUG" }, { "name": "Amphotericin B", "type": "DRUG" }, { "name": "Interferon gamma-1b", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "InterMune", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": null, "sex": "ALL", "summary": "13 Years and older" }, "enrollment_count": 60, "start_date": "2000-01", "completion_date": "2001-07", "has_results": false, "last_update_posted_date": "2009-06-03", "last_synced_at": "2026-09-13T14:35:16.686Z", "location_count": 7, "location_summary": "Birmingham, Alabama • St Louis, Missouri • Camden, New Jersey + 3 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Camden", "state": "New Jersey" }, { "city": "Newark", "state": "New Jersey" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00012467" }, { "nct_id": "NCT00000744", "title": "A Randomized, Prospective, Double-Blind Study Comparing Fluconazole With Placebo for Primary and Secondary Prophylaxis of Mucosal Candidiasis in HIV-Infected Women", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Candidiasis", "Candidiasis, Esophageal", "HIV Infections" ], "interventions": [ { "name": "Fluconazole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": null, "sex": "FEMALE", "summary": "13 Years and older · Female only" }, "enrollment_count": 400, "start_date": null, "completion_date": "1995-12", "has_results": false, "last_update_posted_date": "2021-11-03", "last_synced_at": "2026-09-13T14:35:16.686Z", "location_count": 16, "location_summary": "San Francisco, California • Denver, Colorado • Wilmington, Delaware + 11 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Wilmington", "state": "Delaware" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000744" }, { "nct_id": "NCT01497223", "title": "MGCD290 and Fluconazole Versus Fluconazole Alone for the Treatment of Moderate to Severe Vulvovaginal Candidiasis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Vulvovaginal Candidiasis" ], "interventions": [ { "name": "MGCD290", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "MethylGene Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 220, "start_date": "2011-12", "completion_date": "2013-04", "has_results": false, "last_update_posted_date": "2013-04-04", "last_synced_at": "2026-09-13T14:35:16.686Z", "location_count": 19, "location_summary": "Birmingham, Alabama • San Diego, California • Lake Worth, Florida + 16 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "San Diego", "state": "California" }, { "city": "Lake Worth", "state": "Florida" }, { "city": "North Miami", "state": "Florida" }, { "city": "Augusta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01497223" }, { "nct_id": "NCT05176379", "title": "Endothelial Derived Hyperpolarization Factor and Vascular Control", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Fluconazole 150 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Oklahoma", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "30 Years", "sex": "ALL", "summary": "18 Years to 30 Years" }, "enrollment_count": 30, "start_date": "2022-02-19", "completion_date": "2025-05", "has_results": false, "last_update_posted_date": "2024-07-23", "last_synced_at": "2026-09-13T14:35:16.686Z", "location_count": 1, "location_summary": "Norman, Oklahoma", "locations": [ { "city": "Norman", "state": "Oklahoma" } ], "official_url": "https://clinicaltrials.gov/study/NCT05176379" }, { "nct_id": "NCT04368559", "title": "Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Candidemia", "Mycoses", "Fungal Infection", "Fungemia", "Invasive Candidiasis", "Pneumocystis", "Mold Infection", "Invasive Fungal Disease", "Prophylaxis of Invasive Fungal Infections", "Aspergillus" ], "interventions": [ { "name": "Rezafungin for Injection", "type": "DRUG" }, { "name": "Posaconazole", "type": "DRUG" }, { "name": "Fluconazole", "type": "DRUG" }, { "name": "Trimethoprim-sulfamethoxazole (TMP/SMX)", "type": "DRUG" }, { "name": "Intravenous Placebo", "type": "DRUG" }, { "name": "Oral Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mundipharma Research Limited", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 602, "start_date": "2020-05-11", "completion_date": "2026-01-29", "has_results": false, "last_update_posted_date": "2026-04-13", "last_synced_at": "2026-09-13T14:35:16.686Z", "location_count": 18, "location_summary": "Birmingham, Alabama • Los Angeles, California • Stanford, California + 13 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "Stanford", "state": "California" }, { "city": "Augusta", "state": "Georgia" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT04368559" }, { "nct_id": "NCT00002294", "title": "A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients With AIDS", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Meningitis, Cryptococcal", "HIV Infections" ], "interventions": [ { "name": "Fluconazole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": null, "start_date": null, "completion_date": null, "has_results": false, "last_update_posted_date": "2005-06-24", "last_synced_at": "2026-09-13T14:35:16.686Z", "location_count": 5, "location_summary": "Los Angeles, California • Orange, California • San Diego, California + 2 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Orange", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Sherman Oaks", "state": "California" }, { "city": "Stanford", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00002294" } ] }