{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fluid+Bolus", "query": { "intervention": "Fluid Bolus" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 105, "total_pages": 11, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fluid+Bolus&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-07T16:46:52.475Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01058746", "title": "Randomized Trial of Restrictive Versus Liberal Perioperative Fluid Management for Patients Undergoing Pancreatic Resection", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Pancreatic Cancer" ], "interventions": [ { "name": "restrictive perioperative fluid management", "type": "OTHER" }, { "name": "Liberal perioperative fluid management", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Memorial Sloan Kettering Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 331, "start_date": "2010-01", "completion_date": "2019-09", "has_results": false, "last_update_posted_date": "2019-09-25", "last_synced_at": "2026-09-07T16:46:52.475Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01058746" }, { "nct_id": "NCT05098067", "title": "Capsaicin Cream as an Adjunctive Therapy for Nausea and Vomiting of Pregnancy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hyperemesis Gravidarum", "Nausea Gravidarum", "Vomiting of Pregnancy" ], "interventions": [ { "name": "Capsaicin Topical Cream", "type": "DRUG" }, { "name": "Metoclopramide", "type": "DRUG" }, { "name": "Ondansetron", "type": "DRUG" }, { "name": "Lactated Ringers, Intravenous", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Women and Infants Hospital of Rhode Island", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 30, "start_date": "2022-05-24", "completion_date": "2023-03-01", "has_results": true, "last_update_posted_date": "2024-02-07", "last_synced_at": "2026-09-07T16:46:52.475Z", "location_count": 1, "location_summary": "Providence, Rhode Island", "locations": [ { "city": "Providence", "state": "Rhode Island" } ], "official_url": "https://clinicaltrials.gov/study/NCT05098067" }, { "nct_id": "NCT02972827", "title": "Monitoring Devices in Prediction of Fluid Responsiveness in Severe Sepsis and Septic Shock", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Severe Sepsis", "Septic Shock" ], "interventions": [ { "name": "NICOM/FloTrac", "type": "DEVICE" }, { "name": "Crystalloid Fluid Challenge", "type": "OTHER" } ], "intervention_types": [ "DEVICE", "OTHER" ], "sponsor": "Santa Barbara Cottage Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 38, "start_date": "2015-05", "completion_date": "2022-05", "has_results": false, "last_update_posted_date": "2021-07-02", "last_synced_at": "2026-09-07T16:46:52.475Z", "location_count": 1, "location_summary": "Santa Barbara, California", "locations": [ { "city": "Santa Barbara", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02972827" }, { "nct_id": "NCT03189433", "title": "Efficacy and Safety Study of Ryanodex as Adjuvant Treatment in Subjects With Psychostimulant Drug-Induced Toxicity (PDIT)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Drug Toxicity Psychotropic Agents Psychostimulants" ], "interventions": [ { "name": "Ryanodex (dantrolene sodium) for injectable suspension", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eagle Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2, "start_date": "2017-08-12", "completion_date": "2018-12-31", "has_results": true, "last_update_posted_date": "2021-03-30", "last_synced_at": "2026-09-07T16:46:52.475Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT03189433" }, { "nct_id": "NCT01365793", "title": "Randomized Control Trial of Fluid Therapy for Pediatric Diabetic Ketoacidosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Cerebral Edema", "Diabetic Ketoacidosis" ], "interventions": [ { "name": "0.45% saline replacement fluid", "type": "DRUG" }, { "name": "0.9% saline replacement fluid", "type": "DRUG" }, { "name": "0.45% saline intravenous fluid", "type": "DRUG" }, { "name": "0.9% saline Intravenous fluid", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, Davis", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "17 Years", "sex": "ALL", "summary": "Up to 17 Years" }, "enrollment_count": 1389, "start_date": "2010-11", "completion_date": "2017-01", "has_results": true, "last_update_posted_date": "2018-06-25", "last_synced_at": "2026-09-07T16:46:52.475Z", "location_count": 13, "location_summary": "Sacramento, California • Aurora, Colorado • Wilmington, Delaware + 10 more", "locations": [ { "city": "Sacramento", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Wilmington", "state": "Delaware" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT01365793" }, { "nct_id": "NCT00002618", "title": "Combination Chemotherapy in Treating Pediatric Patients With Advanced-Stage Large Cell Lymphoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Lymphoma" ], "interventions": [ { "name": "filgrastim", "type": "BIOLOGICAL" }, { "name": "cytarabine", "type": "DRUG" }, { "name": "doxorubicin hydrochloride", "type": "DRUG" }, { "name": "leucovorin calcium", "type": "DRUG" }, { "name": "mercaptopurine", "type": "DRUG" }, { "name": "methotrexate", "type": "DRUG" }, { "name": "prednisone", "type": "DRUG" }, { "name": "vincristine sulfate", "type": "DRUG" }, { "name": "low-LET cobalt-60 gamma ray therapy", "type": "RADIATION" }, { "name": "low-LET electron therapy", "type": "RADIATION" }, { "name": "low-LET photon therapy", "type": "RADIATION" } ], "intervention_types": [ "BIOLOGICAL", "DRUG", "RADIATION" ], "sponsor": "Children's Oncology Group", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "21 Years", "sex": "ALL", "summary": "Up to 21 Years" }, "enrollment_count": 242, "start_date": "1994-12", "completion_date": "2006-09", "has_results": false, "last_update_posted_date": "2014-07-24", "last_synced_at": "2026-09-07T16:46:52.475Z", "location_count": 8, "location_summary": "Wichita, Kansas • New Orleans, Louisiana • Asheville, North Carolina + 5 more", "locations": [ { "city": "Wichita", "state": "Kansas" }, { "city": "New Orleans", "state": "Louisiana" }, { "city": "Asheville", "state": "North Carolina" }, { "city": "Charleston", "state": "South Carolina" }, { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00002618" }, { "nct_id": "NCT07274527", "title": "Amnioinfusion's Protective Effects on Respiratory and Longitudinal Pediatric Outcomes After Intrapartum Thick Meconium Exposure", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Neonatal Respiratory Distress Related Conditions", "Meconium", "Perinatal Morbidity", "Neonatal Acidosis", "Cord Blood", "Neonatal Brain Injury", "Maternal Morbidity", "Mechanical Ventilation", "CPAP", "Surfactant", "Perinatal Death", "Amnioinfusion", "NICU Admission" ], "interventions": [ { "name": "Intrauterine pressure catheter", "type": "DEVICE" }, { "name": "Standard obstetric care at discretion of delivery provider", "type": "OTHER" } ], "intervention_types": [ "DEVICE", "OTHER" ], "sponsor": "Medical College of Wisconsin", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 320, "start_date": "2026-05-15", "completion_date": "2030-04-15", "has_results": false, "last_update_posted_date": "2026-05-19", "last_synced_at": "2026-09-07T16:46:52.475Z", "location_count": 1, "location_summary": "Milwaukee, Wisconsin", "locations": [ { "city": "Milwaukee", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT07274527" }, { "nct_id": "NCT02423876", "title": "Epidural Anesthesia Within an Enhanced Recovery Pathway in Reducing Pain in Patients Undergoing Gynecologic Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Intraoperative Complication", "Malignant Female Reproductive System Neoplasm", "Pain" ], "interventions": [ { "name": "Epidural analgesia", "type": "DRUG" }, { "name": "Intraoperative Complication Management and Prevention", "type": "OTHER" }, { "name": "Pain Therapy", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "OTHER", "PROCEDURE" ], "sponsor": "University of Wisconsin, Madison", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 104, "start_date": "2015-03-17", "completion_date": "2022-01-03", "has_results": true, "last_update_posted_date": "2023-09-06", "last_synced_at": "2026-09-07T16:46:52.475Z", "location_count": 1, "location_summary": "Madison, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT02423876" }, { "nct_id": "NCT02542384", "title": "A Study Evaluating the Overall Pain Relief and Safety of Intravenous (IV) CR845 in Patients Undergoing Abdominal Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Post Abdominal Surgery Pain" ], "interventions": [ { "name": "CR845 IV 1 mcg/kg", "type": "DRUG" }, { "name": "CR845 IV 0.5 mcg/kg", "type": "DRUG" }, { "name": "Placebo IV", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Cara Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 451, "start_date": "2015-09", "completion_date": "2018-06", "has_results": false, "last_update_posted_date": "2019-05-31", "last_synced_at": "2026-09-07T16:46:52.475Z", "location_count": 23, "location_summary": "Sheffield, Alabama • New Haven, Connecticut • Bradenton, Florida + 20 more", "locations": [ { "city": "Sheffield", "state": "Alabama" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "Bradenton", "state": "Florida" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Maitland", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02542384" }, { "nct_id": "NCT02054572", "title": "Pharmacokinetics and Excretion of [¹⁴C]Etelcalcetide (AMG 416) in Patients With End Stage Renal Disease (ESRD) Receiving Dialysis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Secondary Hyperparathyroidism in Patients With ESRD on Hemodialysis" ], "interventions": [ { "name": "[¹⁴C]Etelcalcetide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Amgen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 6, "start_date": "2014-02-07", "completion_date": "2014-08-15", "has_results": true, "last_update_posted_date": "2018-08-31", "last_synced_at": "2026-09-07T16:46:52.475Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT02054572" } ] }