{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fluid+administration&page=12", "query": { "intervention": "Fluid administration", "page": 12 }, "page_size": 10 }, "pagination": { "page": 12, "page_size": 10, "total_count": 1417, "total_pages": 142, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fluid+administration&page=13&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fluid+administration&page=11&page_size=10" }, "source": "remote", "last_synced_at": "2026-11-07T17:14:07.218Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02839915", "title": "Leucovorin for the Treatment of Language Impairment in Children With Autism Spectrum Disorder", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Autism Spectrum Disorder" ], "interventions": [ { "name": "Folinic Acid", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Southwest Autism Research & Resource Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "5 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "5 Years to 17 Years" }, "enrollment_count": 56, "start_date": "2020-08-13", "completion_date": "2026-07-31", "has_results": false, "last_update_posted_date": "2026-04-27", "last_synced_at": "2026-11-07T17:14:07.218Z", "location_count": 4, "location_summary": "Phoenix, Arizona • Atlanta, Georgia • Lexington, Massachusetts + 1 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Lexington", "state": "Massachusetts" }, { "city": "Brooklyn", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02839915" }, { "nct_id": "NCT02062710", "title": "Antitussive Effect of a Naturally Flavored Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Cough Reflex Sensitivity" ], "interventions": [ { "name": "diphenhydramine/phenylephrine/cocoa; dextromethorophan; placebo", "type": "DRUG" }, { "name": "diphenhydramine/phenylephrine/cocoa; placebo; dextromethorphan", "type": "DRUG" }, { "name": "dextromethorphan; diphenhydramine/phenylephrine/cocoa; placebo", "type": "DRUG" }, { "name": "dextromethorophan; placebo; diphenhydramine/phenylephrine/cocoa", "type": "DRUG" }, { "name": "placebo; diphenhydramine/phenylephrine/cocoa; dextromethorphan", "type": "DRUG" }, { "name": "placebo; dextromethorphan; diphenhydramine/phenylephrine/cocoa", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Montefiore Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 22, "start_date": "2014-01", "completion_date": "2014-06", "has_results": true, "last_update_posted_date": "2018-02-28", "last_synced_at": "2026-11-07T17:14:07.218Z", "location_count": 1, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02062710" }, { "nct_id": "NCT00029523", "title": "DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid Tumor", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Meningeal Neoplasms" ], "interventions": [ { "name": "Intrathecal (injected into the spinal fluid) DepoCyt", "type": "DRUG" }, { "name": "Intrathecal methotrexate", "type": "DRUG" }, { "name": "Intrathecal cytarabine (also known as ara-C)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pacira Pharmaceuticals, Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2001-04", "completion_date": "2004-11", "has_results": false, "last_update_posted_date": "2007-02-28", "last_synced_at": "2026-11-07T17:14:07.218Z", "location_count": 21, "location_summary": "Phoenix, Arizona • Berkeley, California • Los Angeles, California + 18 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Berkeley", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Washington D.C.", "state": "District of Columbia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00029523" }, { "nct_id": "NCT01128413", "title": "Emergency Department (ED) Flow-directed Fluid Optimization Resuscitation Trial (EFFORT)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Shock" ], "interventions": [ { "name": "Cheetah NICOM® PLRT", "type": "DEVICE" }, { "name": "USCOM ® (Ultrasound Cardiac Output Monitor)", "type": "DEVICE" }, { "name": "Inferior Vena Cava (IVC) Ultrasound Collapsibility", "type": "DEVICE" }, { "name": "CURVES Questionnaire", "type": "BEHAVIORAL" }, { "name": "Lactate Clearance", "type": "BIOLOGICAL" }, { "name": "500ml Normal Saline Bolus", "type": "BIOLOGICAL" }, { "name": "Clinician Discretion Intravenous Fluid Management", "type": "BIOLOGICAL" } ], "intervention_types": [ "DEVICE", "BEHAVIORAL", "BIOLOGICAL" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 22, "start_date": "2010-07", "completion_date": "2013-11", "has_results": true, "last_update_posted_date": "2016-04-01", "last_synced_at": "2026-11-07T17:14:07.218Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT01128413" }, { "nct_id": "NCT00381810", "title": "A Study to Evaluate the Safety of Rituximab Retreatment in Subjects With Systemic Lupus Erythematosus", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Lupus Erythematosus, Systemic" ], "interventions": [ { "name": "Rituximab", "type": "DRUG" }, { "name": "Methylprednisolone", "type": "DRUG" }, { "name": "Acetaminophen", "type": "DRUG" }, { "name": "Diphenhydramine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Genentech, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "16 Years to 75 Years" }, "enrollment_count": 31, "start_date": "2006-06-22", "completion_date": "2012-02-29", "has_results": true, "last_update_posted_date": "2017-08-01", "last_synced_at": "2026-11-07T17:14:07.218Z", "location_count": 11, "location_summary": "Paradise Valley, Arizona • San Leandro, California • Boise, Idaho + 8 more", "locations": [ { "city": "Paradise Valley", "state": "Arizona" }, { "city": "San Leandro", "state": "California" }, { "city": "Boise", "state": "Idaho" }, { "city": "Coeur d'Alene", "state": "Idaho" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00381810" }, { "nct_id": "NCT03379168", "title": "Efficacy of Micro-fragmented Adipose Tissue Injection for Knee Osteoarthritis.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Knee Osteoarthritis" ], "interventions": [ { "name": "Microfragmented Adipose Tissue (Lipogems)", "type": "DEVICE" }, { "name": "Corticosteroid injection", "type": "DRUG" }, { "name": "Saline", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "Dustin L. Richter, MD", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 75, "start_date": "2018-04-01", "completion_date": "2023-10-01", "has_results": true, "last_update_posted_date": "2025-02-13", "last_synced_at": "2026-11-07T17:14:07.218Z", "location_count": 1, "location_summary": "Albuquerque, New Mexico", "locations": [ { "city": "Albuquerque", "state": "New Mexico" } ], "official_url": "https://clinicaltrials.gov/study/NCT03379168" }, { "nct_id": "NCT02222610", "title": "Study of the Efficacy and Tolerability of Intravitreal Injections of Ranibizumab Compared to Intravitreal Injections of Ranibizumab Combined With Targeted Retinal Photocoagulation to Treat Radiation Retinopathy.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Radiation Retinopathy" ], "interventions": [ { "name": "0.5 mg ranibizumab", "type": "DRUG" }, { "name": "Targeted Retinal Photocoagulation (TRP)", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Greater Houston Retina Research", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 40, "start_date": "2014-09-23", "completion_date": "2019-03", "has_results": true, "last_update_posted_date": "2021-03-25", "last_synced_at": "2026-11-07T17:14:07.218Z", "location_count": 4, "location_summary": "Dallas, Texas • Houston, Texas • Katy, Texas + 1 more", "locations": [ { "city": "Dallas", "state": "Texas" }, { "city": "Houston", "state": "Texas" }, { "city": "Katy", "state": "Texas" }, { "city": "The Woodlands", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02222610" }, { "nct_id": "NCT03120585", "title": "Fluid Restriction in Respiratory Distress of the Newborn", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Respiratory Distress Syndrome, Newborn" ], "interventions": [ { "name": "Fluid Management Intervention", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Oklahoma", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "12 Hours", "sex": "ALL", "summary": "Up to 12 Hours" }, "enrollment_count": 65, "start_date": "2017-03-01", "completion_date": "2021-03-31", "has_results": false, "last_update_posted_date": "2021-06-30", "last_synced_at": "2026-11-07T17:14:07.218Z", "location_count": 2, "location_summary": "New York, New York • Lawton, Oklahoma", "locations": [ { "city": "New York", "state": "New York" }, { "city": "Lawton", "state": "Oklahoma" } ], "official_url": "https://clinicaltrials.gov/study/NCT03120585" }, { "nct_id": "NCT04311515", "title": "To Evaluate Safety, Tolerability and Pharmacological Effects of PU AD in Subjects With Mild AD Dementia", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Alzheimer Disease" ], "interventions": [ { "name": "Tau Positron emission tomography (PET)", "type": "RADIATION" }, { "name": "Fluorodeoxyglucose (FDG) Positron emission tomography (PET)", "type": "RADIATION" }, { "name": "Cerebrospinal fluid (CSF) Biomarkers", "type": "DIAGNOSTIC_TEST" }, { "name": "Blood Biomarkers", "type": "DIAGNOSTIC_TEST" }, { "name": "Rating Scales", "type": "BEHAVIORAL" }, { "name": "PU-AD", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "RADIATION", "DIAGNOSTIC_TEST", "BEHAVIORAL", "DRUG" ], "sponsor": "Samus Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "55 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "55 Years to 80 Years" }, "enrollment_count": 4, "start_date": "2020-06-30", "completion_date": "2022-11-15", "has_results": false, "last_update_posted_date": "2022-11-17", "last_synced_at": "2026-11-07T17:14:07.218Z", "location_count": 10, "location_summary": "Boca Raton, Florida • Delray Beach, Florida • Lake Worth, Florida + 6 more", "locations": [ { "city": "Boca Raton", "state": "Florida" }, { "city": "Delray Beach", "state": "Florida" }, { "city": "Lake Worth", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04311515" }, { "nct_id": "NCT01825798", "title": "Treatment of Overweight Induced by Antipsychotic Medication in Young People With Autism Spectrum Disorders (ASD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Overweight", "Autism Spectrum Disorder" ], "interventions": [ { "name": "Metformin", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Holland Bloorview Kids Rehabilitation Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "6 Years to 17 Years" }, "enrollment_count": 60, "start_date": "2013-04", "completion_date": "2015-10", "has_results": true, "last_update_posted_date": "2025-07-16", "last_synced_at": "2026-11-07T17:14:07.218Z", "location_count": 3, "location_summary": "Columbus, Ohio • Pittsburgh, Pennsylvania • Nashville, Tennessee", "locations": [ { "city": "Columbus", "state": "Ohio" }, { "city": "Pittsburgh", "state": "Pennsylvania" }, { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT01825798" } ] }