{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fluoride+Varnishes",
    "query": {
      "intervention": "Fluoride Varnishes"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-11T13:57:17.313Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03448107",
      "title": "Comparative Effectiveness of Treatments to Prevent Dental Caries",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Silver Diamine Fluoride",
          "type": "DEVICE"
        },
        {
          "name": "Fluoride Varnishes",
          "type": "DEVICE"
        },
        {
          "name": "Glass Ionomer",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "NYU College of Dentistry",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "5 Years to 12 Years"
      },
      "enrollment_count": 3345,
      "start_date": "2017-09-20",
      "completion_date": "2023-06-30",
      "has_results": true,
      "last_update_posted_date": "2025-02-26",
      "last_synced_at": "2026-09-11T13:57:17.313Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03448107"
    },
    {
      "nct_id": "NCT07265830",
      "title": "Building Adaptive School-based Interventions for Caries",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Silver Diamine Fluoride (38%)",
          "type": "DEVICE"
        },
        {
          "name": "Glass Ionomer Sealant",
          "type": "DEVICE"
        },
        {
          "name": "Fluoride Varnishes",
          "type": "DEVICE"
        },
        {
          "name": "Hygiene Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "13 Years",
        "sex": "ALL",
        "summary": "5 Years to 13 Years"
      },
      "enrollment_count": 1200,
      "start_date": "2026-08-18",
      "completion_date": "2030-06",
      "has_results": false,
      "last_update_posted_date": "2026-09-10",
      "last_synced_at": "2026-09-11T13:57:17.313Z",
      "location_count": 1,
      "location_summary": "Glenwood Springs, Colorado",
      "locations": [
        {
          "city": "Glenwood Springs",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07265830"
    },
    {
      "nct_id": "NCT03442309",
      "title": "Comparative Effectiveness of School-based Caries Prevention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries",
        "Quality of Life"
      ],
      "interventions": [
        {
          "name": "Silver Diamine Fluoride",
          "type": "DEVICE"
        },
        {
          "name": "Fluoride Varnishes",
          "type": "DEVICE"
        },
        {
          "name": "Glass Ionomer",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "NYU College of Dentistry",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "5 Years to 12 Years"
      },
      "enrollment_count": 7418,
      "start_date": "2019-02-01",
      "completion_date": "2023-06-30",
      "has_results": true,
      "last_update_posted_date": "2025-02-26",
      "last_synced_at": "2026-09-11T13:57:17.313Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03442309"
    },
    {
      "nct_id": "NCT04255251",
      "title": "Effectiveness Silver Diamine Fluoride Versus Sodium Fluoride in Arresting Caries Around Crown Margins in Older Adults",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Caries Roots",
        "Flouride Varnish",
        "Caries; Dentin",
        "Caries Arrested"
      ],
      "interventions": [
        {
          "name": "Silver Diammine Fluoride",
          "type": "DRUG"
        },
        {
          "name": "Fluoride Varnishes",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of New England",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "65 Years to 85 Years"
      },
      "enrollment_count": 200,
      "start_date": "2021-06-26",
      "completion_date": "2024-01-03",
      "has_results": false,
      "last_update_posted_date": "2021-10-05",
      "last_synced_at": "2026-09-11T13:57:17.313Z",
      "location_count": 1,
      "location_summary": "Portland, Maine",
      "locations": [
        {
          "city": "Portland",
          "state": "Maine"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04255251"
    },
    {
      "nct_id": "NCT01629290",
      "title": "In Vivo Comparison of Salivary Fluoride Levels Following the Application of Different 5% NaF Varnishes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Enamel Pro",
          "type": "DEVICE"
        },
        {
          "name": "Duraphat",
          "type": "DEVICE"
        },
        {
          "name": "Vanish",
          "type": "DEVICE"
        },
        {
          "name": "Placebo",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 15,
      "start_date": "2012-06",
      "completion_date": "2015-12",
      "has_results": true,
      "last_update_posted_date": "2017-05-22",
      "last_synced_at": "2026-09-11T13:57:17.313Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01629290"
    },
    {
      "nct_id": "NCT07218068",
      "title": "Intensive Preventative Dental Program Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Dental Diseases"
      ],
      "interventions": [
        {
          "name": "Fluoride varnish",
          "type": "DRUG"
        },
        {
          "name": "Regular Care",
          "type": "OTHER"
        },
        {
          "name": "Medical Oncology Care Team",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 13,
      "start_date": "2021-10-19",
      "completion_date": "2024-07-10",
      "has_results": false,
      "last_update_posted_date": "2025-11-03",
      "last_synced_at": "2026-09-11T13:57:17.313Z",
      "location_count": 1,
      "location_summary": "Charlotte, North Carolina",
      "locations": [
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07218068"
    }
  ]
}