{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fluzone%C2%AE+High+Dose+Quadrivalent", "query": { "intervention": "Fluzone® High Dose Quadrivalent" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 25, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fluzone%C2%AE+High+Dose+Quadrivalent&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-11-05T15:21:13.112Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05050318", "title": "Annual Study for Collection of Serum Samples in Children and Older Adults Receiving the 2021-2022 Formulations of Fluzone Quadrivalent Vaccine and Fluzone High-Dose Quadrivalent Vaccine, Respectively", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Influenza Immunization", "Healthy Volunteers" ], "interventions": [ { "name": "Fluzone Quadrivalent vaccine, No Preservative (0.5-mL dose), 2021-2022 formulation", "type": "BIOLOGICAL" }, { "name": "Fluzone High-Dose Quadrivalent vaccine (0.7-mL dose), 2021-2022 formulation", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "6 Months", "maximum_age": null, "sex": "ALL", "summary": "6 Months and older" }, "enrollment_count": 90, "start_date": "2021-09-08", "completion_date": "2021-11-10", "has_results": true, "last_update_posted_date": "2025-09-12", "last_synced_at": "2026-11-05T15:21:13.112Z", "location_count": 2, "location_summary": "Bardstown, Kentucky • Salt Lake City, Utah", "locations": [ { "city": "Bardstown", "state": "Kentucky" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT05050318" }, { "nct_id": "NCT05553301", "title": "Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5407 in Adult Participants18 Years of Age and Older", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Influenza Immunization" ], "interventions": [ { "name": "Quadrivalent Influenza mRNA Vaccine MRT5407", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Recombinant Influenza Vaccine", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Influenza Standard Dose Vaccine", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Influenza High-Dose Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 560, "start_date": "2022-10-03", "completion_date": "2024-01-19", "has_results": false, "last_update_posted_date": "2025-01-24", "last_synced_at": "2026-11-05T15:21:13.112Z", "location_count": 23, "location_summary": "Rolling Hills Estates, California • San Diego, California • DeLand, Florida + 16 more", "locations": [ { "city": "Rolling Hills Estates", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "DeLand", "state": "Florida" }, { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05553301" }, { "nct_id": "NCT04613206", "title": "High vs. Standard Dose Influenza Vaccine in Adult SOT Recipients", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Immunization; Infection", "Transplantation Infection", "Influenza", "Solid Organ Transplant" ], "interventions": [ { "name": "High Dose Quadrivalent Inactivated Influenza Vaccine", "type": "BIOLOGICAL" }, { "name": "Standard Dose Quadrivalent Inactivated Influenza Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 396, "start_date": "2021-01-11", "completion_date": "2027-12-31", "has_results": false, "last_update_posted_date": "2026-10-02", "last_synced_at": "2026-11-05T15:21:13.112Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT04613206" }, { "nct_id": "NCT07908329", "title": "Intradermal Influenza Vaccination", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Vaccine Reaction" ], "interventions": [ { "name": "MicronJet", "type": "DEVICE" }, { "name": "Fluzone® Quadrivalent", "type": "BIOLOGICAL" }, { "name": "Fluzone® High Dose Quadrivalent", "type": "BIOLOGICAL" } ], "intervention_types": [ "DEVICE", "BIOLOGICAL" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 139, "start_date": "2026-10-01", "completion_date": "2029-05", "has_results": false, "last_update_posted_date": "2026-11-02", "last_synced_at": "2026-11-05T15:21:13.112Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT07908329" }, { "nct_id": "NCT02563093", "title": "Study of Fluzone® Quadrivalent, Fluzone® Intradermal Quadrivalent, and Fluzone® High-Dose, Influenza Vaccines in Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Influenza" ], "interventions": [ { "name": "Fluzone Quadrivalent vaccine, 2015-2016 formulation, No Preservative", "type": "BIOLOGICAL" }, { "name": "Fluzone Intradermal Quadrivalent vaccine, 2015-2016 formulation", "type": "BIOLOGICAL" }, { "name": "Fluzone High-Dose vaccine, 2015-2016 formulation", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 208, "start_date": "2015-09", "completion_date": "2016-07", "has_results": true, "last_update_posted_date": "2016-12-12", "last_synced_at": "2026-11-05T15:21:13.112Z", "location_count": 4, "location_summary": "Santa Rosa, California • Council Bluffs, Iowa • Metairie, Louisiana + 1 more", "locations": [ { "city": "Santa Rosa", "state": "California" }, { "city": "Council Bluffs", "state": "Iowa" }, { "city": "Metairie", "state": "Louisiana" }, { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02563093" }, { "nct_id": "NCT03722589", "title": "Immunogenicity Trial of Egg- Versus Non-Egg-Based Influenza Vaccines Among HCP", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Influenza" ], "interventions": [ { "name": "Flublok", "type": "BIOLOGICAL" }, { "name": "Flucelvax", "type": "BIOLOGICAL" }, { "name": "Fluarix", "type": "BIOLOGICAL" }, { "name": "Fluzone", "type": "BIOLOGICAL" }, { "name": "Fluzone High-Dose", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Centers for Disease Control and Prevention", "sponsor_class": "FED", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 944, "start_date": "2018-09-12", "completion_date": "2020-07-31", "has_results": true, "last_update_posted_date": "2024-07-22", "last_synced_at": "2026-11-05T15:21:13.112Z", "location_count": 2, "location_summary": "Portland, Oregon • Temple, Texas", "locations": [ { "city": "Portland", "state": "Oregon" }, { "city": "Temple", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03722589" }, { "nct_id": "NCT05518500", "title": "A Deep Longitudinal Analysis of Next Generation Influenza Vaccines in Older Adults", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Aging", "Influenza Vaccine", "Dendritic Cell", "Vaccine Response" ], "interventions": [ { "name": "Flu Vaccine (Year 1)", "type": "BIOLOGICAL" }, { "name": "Flu Vaccine (Year 2)", "type": "BIOLOGICAL" }, { "name": "Flu Vaccine (Year 3)", "type": "BIOLOGICAL" }, { "name": "Flu Vaccine (Year 4)", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "The Jackson Laboratory", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "65 Years", "maximum_age": null, "sex": "ALL", "summary": "65 Years and older" }, "enrollment_count": 75, "start_date": "2022-08-31", "completion_date": "2026-12-31", "has_results": false, "last_update_posted_date": "2026-08-03", "last_synced_at": "2026-11-05T15:21:13.112Z", "location_count": 1, "location_summary": "Farmington, Connecticut", "locations": [ { "city": "Farmington", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT05518500" }, { "nct_id": "NCT02831751", "title": "Immunogenicity, Safety, and Tolerability of a Plant-Derived Quadrivalent VLP Influenza Vaccine in Elderly Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Virus Diseases", "RNA Virus Infections", "Respiratory Tract Diseases", "Respiratory Tract Infections" ], "interventions": [ { "name": "30 µg/strain of Quadrivalent VLP Vaccine", "type": "BIOLOGICAL" }, { "name": "60 µg/strain of Quadrivalent VLP Vaccine", "type": "BIOLOGICAL" }, { "name": "FluLaval® Tetra (15 µg/strain)", "type": "BIOLOGICAL" }, { "name": "Fluzone® High-Dose (60 µg/strain)", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Medicago", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "65 Years", "maximum_age": null, "sex": "ALL", "summary": "65 Years and older" }, "enrollment_count": 1001, "start_date": "2016-04", "completion_date": "2017-01", "has_results": false, "last_update_posted_date": "2019-10-25", "last_synced_at": "2026-11-05T15:21:13.112Z", "location_count": 6, "location_summary": "Redding, California • Hollywood, Florida • South Miami, Florida + 3 more", "locations": [ { "city": "Redding", "state": "California" }, { "city": "Hollywood", "state": "Florida" }, { "city": "South Miami", "state": "Florida" }, { "city": "Savannah", "state": "Georgia" }, { "city": "Omaha", "state": "Nebraska" } ], "official_url": "https://clinicaltrials.gov/study/NCT02831751" }, { "nct_id": "NCT04109222", "title": "Collection of Serum Samples From Children and Older Adults Receiving the 2019-2020 Formulations of Fluzone® Quadrivalent and Fluzone® High-Dose Influenza Vaccines, Respectively", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Influenza" ], "interventions": [ { "name": "Fluzone Quadrivalent vaccine, no preservative (0.5-mL), 2019-2020 formulation", "type": "BIOLOGICAL" }, { "name": "Fluzone High-Dose vaccine, 2019-2020 formulation", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "6 Months", "maximum_age": "83 Years", "sex": "ALL", "summary": "6 Months to 83 Years" }, "enrollment_count": 90, "start_date": "2019-09-30", "completion_date": "2019-12-10", "has_results": true, "last_update_posted_date": "2025-09-12", "last_synced_at": "2026-11-05T15:21:13.112Z", "location_count": 2, "location_summary": "Bardstown, Kentucky • Salt Lake City, Utah", "locations": [ { "city": "Bardstown", "state": "Kentucky" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT04109222" }, { "nct_id": "NCT03617523", "title": "Safety and Immunogenicity of Fluzone® Quadrivalent, Flublok® Quadrivalent, and Fluzone® High-Dose, Influenza Vaccines, 2018-2019 Formulations", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Influenza" ], "interventions": [ { "name": "Fluzone Quadrivalent vaccine, 2018-2019 formulation", "type": "BIOLOGICAL" }, { "name": "Flublok Quadrivalent vaccine, 2018-2019 formulation", "type": "BIOLOGICAL" }, { "name": "Fluzone High-Dose vaccine, 2018-2019 formulation", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "6 Months", "maximum_age": null, "sex": "ALL", "summary": "6 Months and older" }, "enrollment_count": 240, "start_date": "2018-09-10", "completion_date": "2018-11-12", "has_results": true, "last_update_posted_date": "2022-03-29", "last_synced_at": "2026-11-05T15:21:13.112Z", "location_count": 3, "location_summary": "Bardstown, Kentucky • Metairie, Louisiana • Salt Lake City, Utah", "locations": [ { "city": "Bardstown", "state": "Kentucky" }, { "city": "Metairie", "state": "Louisiana" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT03617523" } ] }