{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fluzone+High+Dose+Vaccine&page=4",
    "query": {
      "intervention": "Fluzone High Dose Vaccine",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 142,
    "total_pages": 15,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fluzone+High+Dose+Vaccine&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Fluzone+High+Dose+Vaccine&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-15T18:38:17.537Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03312699",
      "title": "Effects of Aging on Primary and Secondary Vaccine Responses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Influenza",
        "Hepatitis A",
        "Typhoid",
        "Healthy Adults"
      ],
      "interventions": [
        {
          "name": "Fluzone® quadrivalent",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Fluzone High Dose",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Fluad",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Vaqta",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Typhim Vi",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Vivotif",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 54,
      "start_date": "2017-09-19",
      "completion_date": "2023-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-12-16",
      "last_synced_at": "2026-11-15T18:38:17.537Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03312699"
    },
    {
      "nct_id": "NCT04109222",
      "title": "Collection of Serum Samples From Children and Older Adults Receiving the 2019-2020 Formulations of Fluzone® Quadrivalent and Fluzone® High-Dose Influenza Vaccines, Respectively",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Influenza"
      ],
      "interventions": [
        {
          "name": "Fluzone Quadrivalent vaccine, no preservative (0.5-mL), 2019-2020 formulation",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Fluzone High-Dose vaccine, 2019-2020 formulation",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Sanofi Pasteur, a Sanofi Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "83 Years",
        "sex": "ALL",
        "summary": "6 Months to 83 Years"
      },
      "enrollment_count": 90,
      "start_date": "2019-09-30",
      "completion_date": "2019-12-10",
      "has_results": true,
      "last_update_posted_date": "2025-09-12",
      "last_synced_at": "2026-11-15T18:38:17.537Z",
      "location_count": 2,
      "location_summary": "Bardstown, Kentucky • Salt Lake City, Utah",
      "locations": [
        {
          "city": "Bardstown",
          "state": "Kentucky"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04109222"
    },
    {
      "nct_id": "NCT02233816",
      "title": "Immunogenicity, Safety and Tolerability of a Plant-Derived Seasonal Virus-Like-Particle Quadrivalent Influenza Vaccine in Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Virus Diseases",
        "RNA Virus Infections",
        "Respiratory Tract Diseases",
        "Respiratory Tract Infections"
      ],
      "interventions": [
        {
          "name": "Low dose of quadrivalent VLP vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Medium dose of quadrivalent VLP vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "High dose of quadrivalent VLP vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Medicago",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "18 Years to 49 Years"
      },
      "enrollment_count": 300,
      "start_date": "2014-07-28",
      "completion_date": "2015-06-22",
      "has_results": false,
      "last_update_posted_date": "2019-11-13",
      "last_synced_at": "2026-11-15T18:38:17.537Z",
      "location_count": 2,
      "location_summary": "Hollywood, Florida • Miami, Florida",
      "locations": [
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02233816"
    },
    {
      "nct_id": "NCT05291676",
      "title": "Systems Investigation of Vaccine Responses in Aging and Frailty",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Influenza"
      ],
      "interventions": [
        {
          "name": "Fluzone",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Fluad",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 96,
      "start_date": "2023-11-06",
      "completion_date": "2029-05",
      "has_results": false,
      "last_update_posted_date": "2026-11-10",
      "last_synced_at": "2026-11-15T18:38:17.537Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05291676"
    },
    {
      "nct_id": "NCT00903552",
      "title": "Trial to Evaluate Safety and Immunogenicity of Trivalent Seasonal Influenza Virus-Like Particle (VLP) Vaccine (Recombinant)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Seasonal Influenza"
      ],
      "interventions": [
        {
          "name": "Influenza VLP Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Novavax",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "18 Years to 49 Years"
      },
      "enrollment_count": 221,
      "start_date": "2009-05",
      "completion_date": "2009-10",
      "has_results": false,
      "last_update_posted_date": "2013-07-18",
      "last_synced_at": "2026-11-15T18:38:17.537Z",
      "location_count": 2,
      "location_summary": "Pembroke Pines, Florida • Baltimore, Maryland",
      "locations": [
        {
          "city": "Pembroke Pines",
          "state": "Florida"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00903552"
    },
    {
      "nct_id": "NCT04101838",
      "title": "B Cell and Antibody Response to Seasonal Influenza Vaccines in Younger and Older Adults",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Influenza"
      ],
      "interventions": [
        {
          "name": "Fluzone",
          "type": "DRUG"
        },
        {
          "name": "Flucelvax",
          "type": "DRUG"
        },
        {
          "name": "Fluzone High-Dose",
          "type": "DRUG"
        },
        {
          "name": "Fluad",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 50,
      "start_date": "2021-04-01",
      "completion_date": "2027-05",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-11-15T18:38:17.537Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04101838"
    },
    {
      "nct_id": "NCT01427309",
      "title": "A Study of Fluzone® High-Dose Vaccine Compared With Fluzone® Vaccine In Elderly Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Influenza"
      ],
      "interventions": [
        {
          "name": "High Dose Trivalent Inactivated Influenza Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Trivalent Inactivated Influenza Vaccine",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Sanofi Pasteur, a Sanofi Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 31989,
      "start_date": "2011-09",
      "completion_date": "2013-11",
      "has_results": true,
      "last_update_posted_date": "2015-04-20",
      "last_synced_at": "2026-11-15T18:38:17.537Z",
      "location_count": 105,
      "location_summary": "Mobile, Alabama • Chandler, Arizona • Glendale, Arizona + 88 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Glendale",
          "state": "Arizona"
        },
        {
          "city": "Glendale",
          "state": "Arizona"
        },
        {
          "city": "Mesa",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01427309"
    },
    {
      "nct_id": "NCT02822105",
      "title": "Safety and Immunogenicity Study of H3N2 M2SR Monovalent Influenza Vaccine in Healthy Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Flu"
      ],
      "interventions": [
        {
          "name": "the H3N2 M2SR monovalent influenza vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "FluGen Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "18 Years to 49 Years"
      },
      "enrollment_count": 96,
      "start_date": "2016-06",
      "completion_date": "2017-11",
      "has_results": false,
      "last_update_posted_date": "2020-08-10",
      "last_synced_at": "2026-11-15T18:38:17.537Z",
      "location_count": 1,
      "location_summary": "Lenexa, Kansas",
      "locations": [
        {
          "city": "Lenexa",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02822105"
    },
    {
      "nct_id": "NCT00551031",
      "title": "Study of Inactivated, Split-Virion Influenza Vaccine and Standard Fluzone® Vaccine in Adult and Elderly Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Influenza",
        "Myxovirus Infection"
      ],
      "interventions": [
        {
          "name": "Split, Inactivated, Trivalent Influenza Vaccine (Intradermal Formulation 1)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Split, Inactivated, Trivalent Influenza Vaccine (Intradermal Formulation 2)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Split, Inactivated, Trivalent Influenza Vaccine (Standard dose)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Split, Inactivated, Trivalent Influenza Vaccine (High-dose)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Sanofi",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2098,
      "start_date": "2007-10",
      "completion_date": "2008-11",
      "has_results": true,
      "last_update_posted_date": "2016-05-16",
      "last_synced_at": "2026-11-15T18:38:17.537Z",
      "location_count": 29,
      "location_summary": "Alabaster, Alabama • Mobile, Alabama • Chandler, Arizona + 26 more",
      "locations": [
        {
          "city": "Alabaster",
          "state": "Alabama"
        },
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00551031"
    },
    {
      "nct_id": "NCT00978120",
      "title": "Safety and Efficacy of an H1N1 Influenza Vaccine in People With Asthma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "H1N1 Influenza Virus"
      ],
      "interventions": [
        {
          "name": "H1N1 vaccine high dose",
          "type": "BIOLOGICAL"
        },
        {
          "name": "H1N1 vaccine low dose",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 390,
      "start_date": "2009-10",
      "completion_date": "2010-09",
      "has_results": true,
      "last_update_posted_date": "2012-08-10",
      "last_synced_at": "2026-11-15T18:38:17.537Z",
      "location_count": 7,
      "location_summary": "Atlanta, Georgia • St Louis, Missouri • Winston-Salem, North Carolina + 4 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00978120"
    }
  ]
}